Midterm Flashcards
examples of primary prevention
immunizations or behavioral counseling to remove risk factors
examples of secondary prevention
screening, early detection, and treatment
examples of tertiary prevention
treatment focused on long-term outcomes and prevention of disease progression and complications
secondary prevention in cardiology
patients have known disease and are being treated or are at very high risk of disease
secondary prevention in neurology
patients who have had a stroke or TIA or who are at very high risk of ischemic stroke
primum non nocere
first, do no harm - nonmaleficence
3 major aspects to consider when screening
the burden of disease, the sensitivity/specificity of the screening test, and the efficacy of treatment
sensitivity
the probability that a patient with the disease will have a positive test (SNOUT) - high sensitivity rules out disease
specificity
the probability that a patient without the disease will test negative (SPIN) - high specificity rules in disease
positive predictive value
likelihood that a person with a positive test has the disease - dependent on prevalence
negative predictive value
likelihood that a person with a negative test does not have the disease - dependent on prevalence
which predictive value is more useful with a low prevalence of disease?
negative predictive value (rules out disease)
predictive value of most screening tests
high negative predictive value
lead time bias
people who are diagnosed with screening survive longer after diagnosis than patients who present with symptoms even if treatment does not make a difference
length time bias
slower-growing cancers are more likely to be found by screening whereas faster-growing cancers usually present between screenings or before it starts
compliance bias
compliant patients have a better prognosis than non-compliant patients regardless of screening
external validity
generalizability - how well the study applies to patients who were not in the study
USPSTF
created in 1984 and make evidence-based recommendations about clinical preventative services excluding vaccines (does not consider cost of services)
CDC
advisory committee on immunization practices
CDC recommends Td/Tdap
a single dose of Tdap in place of Td for all adults age 19+ who have not received Tdap previously followed by Td booster every 10 years
CDC recommends Zoster (Shingles) vaccine
in adults age 50+
CDC recommends MMR vaccine
1-2 doses if born in 1957 or later
CDC recommends Varicella vaccine
age 13+ without evidence of immunity (history chickenpox)
CDC recommends HPV vaccine
in females up to age 26 (or up to age 45 with shared decision making), in males up to age 21, and in men who have sex with men (MSM) up to age 26
CDC recommends Meningococcal vaccine
in adults up to age 21 who are living in college dorms
CDC recommends Hep B vaccine
in adults age 19-59 with diabetes and other adults at high risk
CDC recommends Pneumococcus vaccine
1 dose of PCV-15 or PCV-20 in adults age 65+ (if PCV-15, then followed by 1 dose of PPSV-23), 1 dose of PCV-15 or PCV-20 in adults age 19-64 with certain chronic conditions and in adults 19+ with immunocompromise
live, attenuated vaccines
contain a little version of the organism that has been weakened (attenuated) so that it doesn’t cause disease in patients with a healthy immune system (can cause disease in immunocompromised patients), confer long-lasting immunity with usually only 1-2 doses - MMR and Varicella/Zoster
inactivated vaccines
contain a killed version of the organism, may require several boosters to get long-lasting immunity or to maintain it - IPV, hepatitis A
subunit vaccines
contain part of the organism (often essential antigen) and have less side effects - pertussis
Toxoid vaccines
contain a weakened form of a bacterial toxin to prevent diseases due to bacterial toxins - tetanus and diphtheria
conjugate vaccines
link antigens or toxoids that the immune system does not recognize to polysaccharides preventing the immune system in children and infants from recognizing them - Hib
live attenuated vaccine (MMR, varicella, live zoster, live influenza) contraindications
pregnancy, severe immunodeficiency
potential major vaccine contraindications
allergies to eggs (influenza), gelatin (varicella), baker’s yeast (hep B), neomycin/streptomycin (MMR, IPV), severe immunodeficiency (MMR, varicella, zoster), encephalopathy within 7 days of getting DTP, Tdap, or DTaP, if history of severe side effects such as Guillain-Barre, high fevers, seizures, or prolonged inconsolable crying
precautions to giving vaccines
delay if the patient is moderately to severely ill or if received IVIG
USPSTF recommends cervical cancer screening
in females age 21-65 by Pap every 3 years or Pap-HPV co-testing every 5 years
USPSTF recommends colorectal cancer screening
in adults age 50-75 (grade A) and in adults age 45-49) grade B
USPSTF recommends breast cancer screening
in adults aged 50-74 by mammography every 2 years (grade B)
USPSTF recommends prostate cancer screening
in adults age 55-69 by PSA based on individual decision making (grade C)
USPSTF recommends lung cancer screening
in adults who are smokers/former smokers aged 50-80
USPSTF recommends behavioral counseling for
smoking cessation, healthy diet and physical activity, obesity screening and counseling, STI counseling, fall prevention, and skin cancer prevention
USPSTF recommends screening for
blood pressure, depression, HIV, unhealthy alcohol use, diabetes, intimate partner violence, osteoporosis, AAA, STIs, hepatitis
USPSTF chemoprevention includes
use of statins, tobacco cessation, and aspirin use to prevent ASCVD and colorectal cancer
neonate/newborn
from birth to 28 days of life
infant
29 days to 1 year
early childhood
1-4 years old (preschool or toddler)
middle childhood
5-10 years old
adolescence
10-20 years old
early adolescence
10-14 years old
middle adolescence
15-16 years old
late adolescence
17-20 years old
goals of pediatric visits
disease prevention and detection, health promotion, and anticipatory guidance
components of pediatric visit
interval history, surveillance of development, review of systems, observation of parent/child interaction, physical exam including growth measurements, screening, immunizations, and anticipatory guidance
developmental surveillance
ongoing process done at every pediatric visit
developmental screening
formal process that uses a standardized tool done at specified ages or on a set schedule to identify children at risk for a developmental disorder
main differences in pediatric HPI
history is obtained from the parent and requires asking about both the child’s and parents’ perspectives as child gets older, must note parent-child interaction
components of well child visit
obtain any parental or child concerns as they get older, any changes since last visit, general status, and other priorities
pediatric past medical history
includes all normal components with the addition of prenatal history, birth history, and newborn history (newborn history included for all children age 3 and under and older if pertinent)
prenatal history includes
mother’s age at delivery, previous pregnancy history, maternal illnesses during pregnancy, complications of pregnancy
birth history includes
duration of pregnancy, kind and duration of labor, type of delivery, medications during delivery, condition of child at birth, need for resuscitation at birth, APGAR scores, complications of delivery