MIDTERM

Question 1

Ointments came from a latin word?

Answer 1

Unguentum

Question 2

Semisolid preparations applied on skin and mucous membranes

Answer 2

OINTMENTS

Question 3

Ointment Bases

Answer 3

Oleaginous Bases
Absorption Bases
Water-Removal Bases
Water-Soluble Bases

Question 4

Other termed for oleaginous base

Answer 4

Hydrocarbon Base

Question 5

It is greasy, anhydrous, emollient, occlusive effect, non-water washable

Answer 5

OLEAGINOUS BASE

Question 6

Most common brand name of Petrolatum USP

Answer 6

VASELINE

Question 7

Mixture if semisolid hydrocarbon from petrolatum

Answer 7

PETROLATUM USP/YELLOW PETROLATUM/ PETROLEUM JELLY

Question 8

Bleached form of Petrolatum USP

Answer 8

WHITE PETROLATUM

Question 9

From honeybees/ honeycomb of Apis Mellifera

Answer 9

YELLOW WAX/BEESWAX

Question 10

Honeycomb of?

Answer 10

APIS MELLIFERA

Question 11

Bleached form of yellow wax or bees wax

Answer 11

WHITE WAX

Question 12

It is a combination of yellow petrolatum + yellow wax

Answer 12

YELLOW OINTMENT/SIMPLE OINTMENT

Question 13

White Petrolatum + White Wax

Answer 13

WHITE OINTMENT

Question 14

Greasy
Anhydrous
Emollient
Occlusive Effect
Non-water Washable
(Can absorb small amount of water > will form w/)

Answer 14

ABSORPTION BASE

Question 15

Brand name example of hydrophilic petrolatum

Answer 15

AQUAPHOR

Question 16

Contains:
White wax
White Petrolatum
Stearyl Alcohol
Cholesterol

Answer 16

HYDROPHILIC PETROLATUM (AQUAPHOR)

Question 17

From wool of sheep (Ovis Aries)

Answer 17

ANHYDROUS LANOLIN (WOOLFAT)

Question 18

It contains 0.25% moisture

Answer 18

ANHYDROUS LANOLIN (WOOLFAT)

Question 19

NOTE: HYDROUS LANOLIN 25% MOISTURE

Question 20

•o/w emulsions
• non greasy, non-occlusive, water washable
•can be diluted with large amount of water

Answer 20

WATER-REMOVABLE BASE

Question 21

Example is Hydrophilic Ointment

Answer 21

WATER-REMOMABLE BASE

Question 22

the wool of sheep (scientific name)

Answer 22

Ovis aries

Question 23

lipid-free
greaseless
Non-occlusive
Water washable

Answer 23

WATER-SOLUBLE BASE

Question 24

For incorporation of solid substances

Answer 24

WATER-SOLUBLE BASE

Question 25

MW of less than 600 <600

Answer 25

CLEAR, COLORLESS LIQUID

Question 26

CLEAR COLORLESS LIQUID

Answer 26

LESS THEN 600 (<600)

Question 27

Molecular weight more than 1000 >1000

Answer 27

WAX-LIKE, WHITE SOLID

Question 28

WAX LIKE, WHITE SOLID

Answer 28

MORE THEN 1000 >1000

Question 29

Molecular weight 600-1000

Answer 29

SEMI SOLID

Question 30

2 methods of manufacture of ointments

Answer 30

INCORPORATION FUSION

Question 31

Use of ointment roller mills to mix heat-sensitive ointment bases

Answer 31

INCORPORATION

Question 32

Use of steam-jacketed kettles to melts anhydrous ointment bases and cooling gradually until congealed.

Answer 32

FUSION

Question 33

Semi-solid creams form in which the drug is dissolved or dispersed in either o/w or w/o emulsion base or any type of water-removable base.

Answer 33

CREAMS

Question 34

More liquid in consistency than ointment therefore more spreadable to the skin.

Answer 34

CREAMS

Question 35

It is put in larger areas of the skin

Answer 35

CREAMS

Question 36

Dry or scaly areas of the skin

Answer 36

OINTMENT

Question 37

For whipping or oozing surfaces

Answer 37

CREAMS

Question 38

Water will evaporate a thin film of stearic acid will remain

Answer 38

VANISHING CREAM

Question 39

Large percentage of H2O Humectant (polyhedric alcohol) Stearic Acid

Answer 39

VANISHING CREAM

Question 40

w/o base

Answer 40

COLD CREAM/ PETROLATUM ROSE WATER OINTMENT

Question 41

Other term for cold cream

Answer 41

PETROLATUM ROSE WATER OINTMENT

Question 42

STEARIC ACID IS A FATTY ACID

Question 43

Clear, colorless dispersion systems which are rendered jelly-like by the addition of a gelling agent

Answer 43

GELS

Question 44

Also known as gel-sel formation

Answer 44

THIXOTROPY

Question 45

Property of gel (jelly like consistency)

Answer 45

THIXOTROPY

Question 46

Semisolid preps applied on the skin container a larger proportion of solid materials >25%

Answer 46

PASTE

Question 47

>25%

Answer 47

PASTE

Question 48

It is stiffer than ointment

Answer 48

PASTE

Question 49

Example of Paste

Answer 49

ZnO Paste

Question 50

Topical protectant (treatment and protection of diaper rash)

Answer 50

ZnO Paste

Question 51

A lotion that has ZnO paste?

Answer 51

CALAMINE LOTION

Question 52

Antipruritic that contains ZnO

Answer 52

CALAMINE LOTION

Question 53

Are applied to the skin for the long term. They are melted before application, cooled to slightly above body temperature and applied to the affected area with a fine brush.

Answer 53

GLYCEROGELATINS

Question 54

Examples of glycerogelatin

Answer 54

ZINC GELATIN BOOT

Question 55

Treatment for varicose ulcers?

Answer 55

ZINC GELATIN BOOT

Question 56

Components of glycerogelatin

Answer 56

40% Glycerin 35% Water 15% Gelatin 10% API

Question 57

Solid masses inserted into a body cavity in which they melt at body temperature or dissolve into the aqueous secretions of the body orifice.

Answer 57

SUPPOSITOTIES

Question 58

It is given when oral route is not possible : coma, vomiting, infants

Answer 58

SUPPOSITORIES

Question 59

Types of suppositories.

Answer 59

RECTAL VAGINAL URETHRAL

Question 60

It is given when oral route is not possible:

Answer 60

COMA VOMITING INFANTS

Question 61

Bullet/Torpedo

Answer 61

RECTAL

Question 62

Globular/Ovoid/Cone

Answer 62

VAGINAL

Question 63

Pencil-like

Answer 63

URETHRAL

Question 64

Weight of rectal suppositories

Answer 64

A-2g C-1g

Question 65

Size of rectal suppositories

Answer 65

A-32mm C-16mm

Question 66

Weight of Vaginal Suppositories

Answer 66

5g

Question 67

Weight of Urethral suppositories

Answer 67

M-4g F-2g

Question 68

Size of Urethral Suppositories

Answer 68

M-140mm F-70mm

Question 69

-Rectal, urethral -Melts at body temperature

Answer 69

OLEAGINOUS

Question 70

4 types of oleaginous base

Answer 70

COCOA BUTTER WECOBEE WITEPSOL GLYCERYL MONOPALMITATE

Question 71

From seeds of theobroma cacao

Answer 71

CACAO BUTTER

Question 72

Most common base for rectal suppositories

Answer 72

COCOA BUTTER

Question 73

solid 32C, melts at 34-35C

Answer 73

COCOA BUTTER

Question 74

Cocoa butter is from the seed of?

Answer 74

THEOBROMA CACAO

Question 75

More than 1 crystal form?

Answer 75

Polymorphism

Question 76

Mixture of triglyceride. From coconut

Answer 76

WECOBEE

Question 77

Mixture of saturated fatty acid. Major component: Lauric Acid

Answer 77

WITEPSOL

Question 78

Common base of urethral suppository

Answer 78

WATER-SOLUBLE/MISCIBLE

Question 79

Most common base for pessaries

Answer 79

GLYCERINATED GELATIN

Question 80

It is an alternative suppository

Answer 80

POLYETHYLENE GLYCOL (PEG)

Question 81

METHODS OF PREPARATION OF SUPPOSITORIES:

Answer 81

HAND MOLDING COMPRESSION MOLDING POUR/MELT MOLDING

Question 82

oldest; simplest form of the preparation of suppositories

Answer 82

HAND MOLDING

Question 83

Disadvantage: variance in appearnace

Answer 83

HAND MOLDING

Question 84

It avoids hear Problem: air entrapment;weight variation

Answer 84

COMPRESSION MOLDING

Question 85

-the most common method of suppositories. -base is melted and poured to molds -Lubricant is needed (mineral oil)

Answer 85

POUR/MELT MOLDING