MIDTERM Flashcards

1
Q

Ointments came from a latin word?

A

Unguentum

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2
Q

Semisolid preparations applied on skin and mucous membranes

A

OINTMENTS

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3
Q

Ointment Bases

A

Oleaginous Bases
Absorption Bases
Water-Removal Bases
Water-Soluble Bases

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4
Q

Other termed for oleaginous base

A

Hydrocarbon Base

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5
Q

It is greasy, anhydrous, emollient, occlusive effect, non-water washable

A

OLEAGINOUS BASE

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6
Q

Most common brand name of Petrolatum USP

A

VASELINE

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7
Q

Mixture if semisolid hydrocarbon from petrolatum

A

PETROLATUM USP/YELLOW PETROLATUM/ PETROLEUM JELLY

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8
Q

Bleached form of Petrolatum USP

A

WHITE PETROLATUM

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9
Q

From honeybees/ honeycomb of Apis Mellifera

A

YELLOW WAX/BEESWAX

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10
Q

Honeycomb of?

A

APIS MELLIFERA

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11
Q

Bleached form of yellow wax or bees wax

A

WHITE WAX

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12
Q

It is a combination of yellow petrolatum + yellow wax

A

YELLOW OINTMENT/SIMPLE OINTMENT

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13
Q

White Petrolatum + White Wax

A

WHITE OINTMENT

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14
Q

Greasy
Anhydrous
Emollient
Occlusive Effect
Non-water Washable
(Can absorb small amount of water > will form w/)

A

ABSORPTION BASE

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15
Q

Brand name example of hydrophilic petrolatum

A

AQUAPHOR

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16
Q

Contains:
White wax
White Petrolatum
Stearyl Alcohol
Cholesterol

A

HYDROPHILIC PETROLATUM (AQUAPHOR)

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17
Q

From wool of sheep (Ovis Aries)

A

ANHYDROUS LANOLIN (WOOLFAT)

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18
Q

It contains 0.25% moisture

A

ANHYDROUS LANOLIN (WOOLFAT)

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19
Q

NOTE: HYDROUS LANOLIN 25% MOISTURE

A
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20
Q

•o/w emulsions
• non greasy, non-occlusive, water washable
•can be diluted with large amount of water

A

WATER-REMOVABLE BASE

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21
Q

Example is Hydrophilic Ointment

A

WATER-REMOMABLE BASE

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22
Q

the wool of sheep (scientific name)

A

Ovis aries

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23
Q

lipid-free
greaseless
Non-occlusive
Water washable

A

WATER-SOLUBLE BASE

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24
Q

For incorporation of solid substances

A

WATER-SOLUBLE BASE

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25
Q

MW of less than 600 <600

A

CLEAR, COLORLESS LIQUID

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26
Q

CLEAR COLORLESS LIQUID

A

LESS THEN 600 (<600)

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27
Q

Molecular weight more than 1000
>1000

A

WAX-LIKE, WHITE SOLID

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28
Q

WAX LIKE, WHITE SOLID

A

MORE THEN 1000
>1000

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29
Q

Molecular weight 600-1000

A

SEMI SOLID

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30
Q

2 methods of manufacture of ointments

A

INCORPORATION
FUSION

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31
Q

Use of ointment roller mills to mix heat-sensitive ointment bases

A

INCORPORATION

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32
Q

Use of steam-jacketed kettles to melts anhydrous ointment bases and cooling gradually until congealed.

A

FUSION

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33
Q

Semi-solid creams form in which the drug is dissolved or dispersed in either o/w or w/o emulsion base or any type of water-removable base.

A

CREAMS

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34
Q

More liquid in consistency than ointment therefore more spreadable to the skin.

A

CREAMS

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35
Q

It is put in larger areas of the skin

A

CREAMS

36
Q

Dry or scaly areas of the skin

A

OINTMENT

37
Q

For whipping or oozing surfaces

A

CREAMS

38
Q

Water will evaporate a thin film of stearic acid will remain

A

VANISHING CREAM

39
Q

Large percentage of H2O
Humectant (polyhedric alcohol)
Stearic Acid

A

VANISHING CREAM

40
Q

w/o base

A

COLD CREAM/ PETROLATUM ROSE WATER OINTMENT

41
Q

Other term for cold cream

A

PETROLATUM ROSE WATER OINTMENT

42
Q

STEARIC ACID IS A FATTY ACID

A
43
Q

Clear, colorless dispersion systems which are rendered jelly-like by the addition of a gelling agent

A

GELS

44
Q

Also known as gel-sel formation

A

THIXOTROPY

45
Q

Property of gel (jelly like consistency)

A

THIXOTROPY

46
Q

Semisolid preps applied on the skin container a larger proportion of solid materials >25%

A

PASTE

47
Q

> 25%

A

PASTE

48
Q

It is stiffer than ointment

A

PASTE

49
Q

Example of Paste

A

ZnO Paste

50
Q

Topical protectant (treatment and protection of diaper rash)

A

ZnO Paste

51
Q

A lotion that has ZnO paste?

A

CALAMINE LOTION

52
Q

Antipruritic that contains ZnO

A

CALAMINE LOTION

53
Q

Are applied to the skin for the long term. They are melted before application, cooled to slightly above body temperature and applied to the affected area with a fine brush.

A

GLYCEROGELATINS

54
Q

Examples of glycerogelatin

A

ZINC GELATIN BOOT

55
Q

Treatment for varicose ulcers?

A

ZINC GELATIN BOOT

56
Q

Components of glycerogelatin

A

40% Glycerin
35% Water
15% Gelatin
10% API

57
Q

Solid masses inserted into a body cavity in which they melt at body temperature or dissolve into the aqueous secretions of the body orifice.

A

SUPPOSITOTIES

58
Q

It is given when oral route is not possible : coma, vomiting, infants

A

SUPPOSITORIES

59
Q

Types of suppositories.

A

RECTAL
VAGINAL
URETHRAL

60
Q

It is given when oral route is not possible:

A

COMA
VOMITING
INFANTS

61
Q

Bullet/Torpedo

A

RECTAL

62
Q

Globular/Ovoid/Cone

A

VAGINAL

63
Q

Pencil-like

A

URETHRAL

64
Q

Weight of rectal suppositories

A

A-2g
C-1g

65
Q

Size of rectal suppositories

A

A-32mm
C-16mm

66
Q

Weight of Vaginal Suppositories

A

5g

67
Q

Weight of Urethral suppositories

A

M-4g
F-2g

68
Q

Size of Urethral Suppositories

A

M-140mm
F-70mm

69
Q

-Rectal, urethral
-Melts at body temperature

A

OLEAGINOUS

70
Q

4 types of oleaginous base

A

COCOA BUTTER
WECOBEE
WITEPSOL
GLYCERYL MONOPALMITATE

71
Q

From seeds of theobroma cacao

A

CACAO BUTTER

72
Q

Most common base for rectal suppositories

A

COCOA BUTTER

73
Q

solid 32C, melts at 34-35C

A

COCOA BUTTER

74
Q

Cocoa butter is from the seed of?

A

THEOBROMA CACAO

75
Q

More than 1 crystal form?

A

Polymorphism

76
Q

Mixture of triglyceride. From coconut

A

WECOBEE

77
Q

Mixture of saturated fatty acid. Major component: Lauric Acid

A

WITEPSOL

78
Q

Common base of urethral suppository

A

WATER-SOLUBLE/MISCIBLE

79
Q

Most common base for pessaries

A

GLYCERINATED GELATIN

80
Q

It is an alternative suppository

A

POLYETHYLENE GLYCOL (PEG)

81
Q

METHODS OF PREPARATION OF SUPPOSITORIES:

A

HAND MOLDING
COMPRESSION MOLDING
POUR/MELT MOLDING

82
Q

oldest; simplest form of the preparation of suppositories

A

HAND MOLDING

83
Q

Disadvantage: variance in appearnace

A

HAND MOLDING

84
Q

It avoids hear
Problem: air entrapment;weight variation

A

COMPRESSION MOLDING

85
Q

-the most common method of suppositories.
-base is melted and poured to molds
-Lubricant is needed (mineral oil)

A

POUR/MELT MOLDING