Midterm Flashcards

1
Q

What is life expectancy vs lifespan

A

Life expectancy has improved over the past 150 years.
• Life expectancy for men for both males and females in Canada
continues to rise.

Life expectancy and IMR are both measures of population health
• Life expectancy is an average; the inclusion of a high IMR in
calculating life expectancy artificially decreases life expectancy

Lifespan is the number of years 
that, as a species, we are 
biologically wired to live
• The maximum human lifespan has 
remained more or less the same for 
thousands of years; life expectancy, 
on the other hand, continues to rise
• Life expectancy ≠ Lifespan
• Jeanne Calment was a French 
supercentenarian who lived to be 
122!
• ~120 is thought to be the maximum 
human lifespan, but we don’t know 
with certainty. Researchers are 
learning more through studies of 
super-centenarians.
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2
Q

What caused increase life expectancy between 1920 and 2010

A

The large increase in life expectancy between 1920 and
2010 was due to public health achievements (like
antibiotic use and vaccines) as well as a decreasing
infant mortality rate (IMR), ~9% in 1920; ~2% in1960; and
~0.5% in 2007

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3
Q

What is health

A

The overall condition of the body or mind and
the presence or absence of illness or injury
• Historically viewed as the absence of disease (i.e. more of a
state than a process)
• According to the World Health Organization
(WHO): “a state of complete physical, mental
and social well-being and not merely the
absence of disease or infirmity”.

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4
Q

What is the old model vs new mldel of health. Explain

A

Historically, a medical model of health predominated
• Health was viewed as the absence of disease
• You see your physician when you have signs or symptoms of
disease
• Signs: something you can see
• Symptoms: something you feel
• In the medical model, the physician is responsible for your
health, which is achieved through prescribed treatment
• In this model, the goal is to prevent morbidity (sickness) and
mortality (death)
• Focused on the disorder rather than on the person

1970s: A major shift in the concept of health occurred with
the emergence of the field of Health Promotion
- “The process of enabling people to increase control
over and to improve their health” -WHO
• Involves empowerment, community support, healthy public
policy, supportive environments, knowledge translation,
identification of risk factors
• Unlike the medical model, focused on prevention instead
of treatment, empowers the individual to be responsible
for their health
• Relates the main causes of mortality in a population to
known risk factors

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5
Q

What are the 3 groups of preventing health and what are their jobs

A

At the personal level, it is the responsibility of the
person to change their health behaviours to reduce
risk
• At the community level, health promoters can target
high risk groups and focus on prevention and/or
early detection
• At the health-care provider level, physicians can act
as a resource to raise awareness and impart
knowledge of risk factors

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6
Q

What are the social dterminants of health

A
  1. Income
  2. Education
  3. Job security
  4. Early childhood development
  5. Food insecurity
  6. Housing
  7. Social exclusion
  8. Social safety net
  9. Health services
  10. Indigenous status
  11. Gender
  12. Ethnicity
  13. Disability
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7
Q

What is wellness

A

Wellness involves optimal health and vitality, encompassing
all the dimensions of wellbeing
• Largely determined by decisions you make about how you live
• e.g. You can reduce your risk of cancer later in life by eating healthy,
exercising and having available screening tests
• Enhanced wellness involves controlling risk factors that
contribute to disease or injury
• e.g. smoking, drug and alcohol use or abuse, physical inactivity,
poor nutritional choices
• Like health, viewed as more of a process than a state
• You can and must play an active role in decisions related to
each dimension of your wellness!

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8
Q

What 7 dimensions of wellness provide a holistic view on health

A
  • Physical: __________________
  • Emotional: _________________
  • Intellectual: _________________
  • Interpersonal: _______________
  • Spiritual: ___________________
  • Environmental: ______________
  • Financial: __________________
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9
Q

What are the leading causes of death in canada

A

Cancer and heart disease

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10
Q

What factors imrpve the likelyhold lf behaviour change

A

Self-efficacy

Internal locus of control/reinforcement

Self-talk

Support

Identify and overcome barriers

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11
Q

What are smart goals

A
Specific
Measurable 
Attainable 
Reasonable 
Time bound
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12
Q

What is the hierarchy of evidence

A
  1. Experimental: Uses the scientific method and a
    well-designed research study
  2. Epidemiological: Seeks to find relationships
    between variables by looking at trends within
    populations (observations only)
  3. Clinical: Evidence from health care
    professionals and clinicians
  4. Personal: Something you experienced
    personally
  5. Anecdotal: Something someone else
    experienced and told you about
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13
Q

What is an example of experimental evidence

A

Scientific method

The ultimate study design includes:

  1. A randomized study group
  2. Double-blinding & placebo
  3. Cross-over
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14
Q

What are the steps of epidimiological evidence (smoker example)

A
  1. Strength of association: Is smoking is strongly associated with
    lung cancer? Yes.
  2. Dose-response: Does the risk for lung cancer increase the more
    cigarettes a person smokes? Yes.
  3. Consistency: Do many studies link smoking to lung cancer? Yes.
  4. Temporally correct: Is the timing right? Yes. Lung cancer doesn’t
    develop overnight, but usually after years or decades.
  5. Specificity: Is the increased risk is specific to smokers? Yes.
  6. Biological plausibility: Is there a mechanism that could explain
    the cause and effect? Yes. (See Unit 5, Cancer)
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15
Q

Explain clinical evidence

A

Clinical evidence comes from the experience of
clinicians (physicians, dentists, chiropractors,
psychologists, athletic trainers, and so on).
• Often, clinical evidence is consistent with scientific
evidence; however, many clinical procedures have
not been tested scientifically.
• In many cases, the clinicians have taken science
courses but have in most cases they not been
trained as research scientists.
• Clinicians and scientists often work together to
improve healthcare.

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16
Q

Explain personal and anecdotal evidence

A

Personal experience
• Something you have experienced yourself
• e.g. Maybe taking Tylenol on an empty stomach
makes you nauseous, so you don’t take Tylenol
without food
Anecdotal evidence
• Something someone else tells you happened to them
• e.g. Jenny McCarthy (TV personality) has contributed
to the spread of misinformation that wrongly connects
vaccinations and autism
• As a result of so-called anti-vaxxers, we now have the
highest levels of measles infections seen in decades
• Measles is preventable and the MMR vaccine is safe.

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17
Q

How to asses credibility

A
What is the source 
How often is the site updated 
Is the site promotional
What do the other sources say
Does this site conform to a set of criteria for accuracy
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18
Q

What are the 5 guiding principles of the Canada health act

A
Public administration 
Comprihensiveness 
Universality 
Portability 
Accessibility
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19
Q

Describe the importance of self medication

A

Self-medication with over-the-counter (OTC) treatments is an important
part of healthcare
• Non-prescription OTC drugs are medications that Health Canada has
determined to be safe for use without a physicians prescription
• During any six-month period, about two-thirds of Canadians use one or
more OTC drugs
• Many OTC drugs are highly effective in relieving symptoms and some
are effective in curing illnesses (many were formerly prescription drugs)
• Generic drugs must meet the same Health Canada standards as their
brand name (often more expensive) counterparts
• Any drug has potential side effects; always read labels and follow
directions carefully
• Do not exceed the recommended dose and use caution if you are
taking other medications or supplements

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20
Q

What is environmental health

A

The collective interactions of humans with the environment and the short and long run concequences of those interactions

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21
Q

What factors contribute to population growth

A
Fertility rate 
Fertility rates and infant mortality rates are highest in the 
least developed countries
Lack of family planning resources
An increase in the standard of living typically leads to a 
fall in the rate
Lower death rates
Better medical care
Better socio-economic status
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22
Q

What are the main environmental impacts of humans

A
Energy Resource Use and 
Management
Air Pollution and Water 
Pollution
Ozone Depletion
Climate change/Global 
Warming
Toxic Substance and 
Hazardous Waste 
Management
Noise and light pollution
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23
Q

What types of energy are there and explain

A
Non-renewables:
Oil, gas, coal, hydro- electric, nuclear
About 41% of the energy we use in Canada 
comes from oil 
(Natural Resources Canada, 2020)

Renewables:
Solar, wind, water and wave, geothermal,
biomass and bio fuels from renewable
sources
About 17% of the energy we use in Canada
comes from renewables (Natural Resources
Canada, 2020)

Alternate Fuels:
Ethanol

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24
Q

What are the impacts of human energy consumption

A
Pollutants
De-forestation
Waste products
Sewage
Solid waste
Toxic waste (e.g. heavy metals, PCBs, pesticides, radioactive 
waste)
Extraction methods can pose further environmental risks
Decreased bio-diversity 
Eco-system impacts
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25
Q

How do we reduce energy consumption

A
Use public transit, car pool
Turn the heat down wear a sweater
Turn off lights
Use high-efficiency lighting
Hang clothes to dry
Wash and dry dishes by hand
Choose renewable energy sources
Consider e-vehicles
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26
Q

What is municipal vs hazardous waste

A

Municipal= biodegradable, recycling, e-waste

Hazardous=nuclear biological and chemical

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27
Q

What are some affects of pollution

A

Ozone pollution
Thinning lf the ozone
Acid rain
Global warming and greenhouse affect

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28
Q

What is nitrogen oxide mixed with sunlight

A

Ozone… and ground level ozone is the primary component of smog which leads to astma and lung infection

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29
Q

What is particule matter and what is it linked too

A

Ash smoke pollen and dust

Asthma bronchitis and allergies

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30
Q

Carbon monoxide

A

Very poisonous and linked to headaches, impaired visuals and increased risk of CVD

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31
Q

Sulfur oxides

A

Main cause of acid rain
Produced by combustion of oil and other fuels
Linked to lung and cardiovascualr disease

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32
Q

Nigrogen oxides

A

Also a component of acid rain
Precursor for ozone
Produced by engine exhausts

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33
Q

Chlorofluorocarbons (CFCS)

A

Destroys ozone layer

Coolants
Foaming
Aerosol sprays
Solvants

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34
Q

Ehat are the main sources of chemical pollution

A

Pesticides asbestos lead mercury PCBs trihalomethanes BPA

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35
Q

What are the main sources of radiation

A
X rays
Radon
Cell phones
Microwave ovens 
Computor monitos 
Nuclear weapons and energy
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36
Q

What is pain threashold for sound

A

120 decibles

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37
Q

What happens at 80 decibles over long periods

A

Hearing loss

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38
Q

When does light pollution occur

A

When articial illumination enters the night sky and reflects off airborn water droplets and dust partciles

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39
Q

What does light pollution affect

A

Sleep
Melatonin
Migratory flight path of birds

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40
Q

What is emotional vs psyc health

A

Emotional & Psychological Health
Emotional health: Feelings, Moods
Psychological health: Thoughts
Accurate view of reality
Ability to respond to life challenges
Ability to develop rational strategies for living
Our capacity to think, feel and behave in ways
that contribute to our ability to enjoy life and
manage challenges

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41
Q

What is the maslow pyramid of needs

A
1960s: Abraham Maslow 
described a new ideal of mental health that encouraged 
individuals to fulfill their 
potential
Defined a hierarchy of needs in 
order of decreasing importance
Physiological needs
Safety
Being loved
Maintaining self esteem
Self-actualization
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42
Q

What is a psyc disorder

A

A mental disorder is a persistent disturbance or dysfunction
in behaviour, thoughts or emotions that causes significant
distress or impairment
Historically often conceptualized as a result of religious or
supernatural forces, possession by demons or spirits; often
cruelly punished (e.g. institutionalization)
Such views now largely replaced by medical views
Disorders are now viewed as having biological and
environmental causes, defined symptoms, diagnoses and
possible cures
Stigmas surrounding mental illness remain

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43
Q

What are the categories of mental health disorders

A

Anxiety and phobic disorders (~12% of Canadians)
Panic disorders (~2-4%)
Obsessive compulsive disorder (~2%)
Depressive and bipolar (mood) disorders (~15-20%)
Psychotic disorders (e.g. Schizo
Suicide (4000/year)

1/5 canadiens will have mhi in their life
1/2 people who feel they suffer from axiety have never seen a doctor

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44
Q

What is GAD

A
Generalized Anxiety Disorder:
Chronic, irrational worry about 
daily events (work, social 
relationships, finances)
Extreme agitation, fatigue, 
feelings of sadness and 
depression; nausea, trembling, 
muscle tension, headache
Affects ~2.5% of Canadians
Treatments: therapy (e.g. CBT), 
benzodiazepines, antidepressants
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45
Q

What is OCD

A
Obsessive Compulsive 
Disorder:
Obsessions (e.g. cleanliness)
Compulsions (e.g. must keep 
everything clean)
Rituals (e.g. Lysol in diagonal motion, 
vinegar in circular motion)
~2% of NorthAmericans
Treatments: CBT, antidepressants
Howie Mandel has described his OCD 
challenges elated to germs
Leonardo DiCaprio has described his 
challenges with compulsions
46
Q

What is panic disorder

A

Panic Disorder:
Recurrent panic attacks
without warning
Chest pain, heart palpitations,
shortness of breath, dizziness, feeling
of impending doom
Treatments: CBT, anti-anxiety drugs
Agoraphobia: A type of panic disorder
that involves individual avoiding social
situations (e.g. riding the bus or flying)
due to fear of having a panic attack and not being able to escape or acess medical aid

47
Q

Phobias

A
Marked, persistent, excessive fear and 
avoidance of specific objects, activities or
situations
Social phobias: paralyzing fear related to 
social situations (e.g. public speaking)
Affects 8-13% of Canadians
Specific (simple) phobias: e.g. fear of 
spiders, heights, dark, water
Can cause extreme anxiety and panic
13% of Canadians will have a phobia
Preparedness Theory describes how fear
may have benefited our ancestors
48
Q

Depressive disorders

A

Depressive symptoms:
feelings of helplessness, hopelessness, extreme guilt
disturbed sleep; changes in eating patters; weight loss
restlessness or fatigue
anhedonia; loss of enjoyment of usual activities
inability to enjoy life
suicidal thoughts
affect 11% of Canadians aged 15 and older
Seasonal Affective Disorder (SAD; 15% of Canadians)
Postpartum Depression (~1/4 new mothers)
Depressive disorders are associated with an imbalance of neurotransmitters

49
Q

Bipolar disorder

A
Bipolar disorder (formerly called 
manic depressive)
Periods of depression, followed by
mania
Mania: extreme euphoria, rapid 
speech, lack of need to sleep;
grandiosity
Affects 1-3% of Canadians
Typically starts in adolescence
or early adulthood
Treatments: CBT; lithium carbonate; 
anticonvulsants, tranquilizers
50
Q

Schizophrenia

A
Can range from mild to severe
A psychotic (break from reality)
disorder that profoundly impairs
sense of reality
Onset is typically between age 16-30
Complex set of causal factors
Genetic factors may predispose
Social isolation, drug use, traumatic
event(s) may exacerbate/accelerate 
progression
Disorganized thoughts, inappropriate 
emotions, delusions, hallucinations 
(e.g. hearing voices), deteriorating 
function; sometimes catatonia 
Affects ~1% of the population
51
Q

Symptoms of schizophrenia

A

Positive (symptoms present that should be absent)
Hallucinations (auditory, visual, taste)
Delusions (patently false beliefs, e.g. I am Joan of Arc)
Disorganized speech (e.g. I am taking a mental rest
after a carter assignment of quill. You know, a penwrap.
[ ] I am made of flesh and blood.
Grossly disorganized behaviour (e.g. childlike
silliness, masturbation in public)
Negative (symptoms absent that should be present)
Lack of motivation
Blunted feelings
Depression
Social withdrawal

52
Q

What are the types od therapists

A

Psychiatrists: Have a medical degree (M.D);
can prescribe drugs
Psychologists: Have an advanced degree in
psychology (Ph.D.; M.Sc.); can offer
behavioural therapy (e.g. CBT) but not drugs
Social workers: Training in counselling and
usually licensed and registered
Counsellors: Various kinds; often, no set
specialized training or licensing required

53
Q

What are the types of theraputics

A
Anti depressants
Mood stabalizers 
Antipsychotics
Anxiolytics
Stimulants
54
Q

What is cognitive behavioural therapy

A

Variety of techniques that work towards changing negative patterns of thought and action to positive

55
Q

Suicide

A
Second leading cause of death for
those aged 15-34 in Canada
Often associated with depressive 
disorders or major life crises
Feelings of hopelessness, rejection,
or lack of self-worth
3x more likely in men; 6x times 
higher among Indigenous youth
~15% of Canadian adults report 
considering suicide
56
Q

Main components of stress

A

Stress: Any situation that disrupts homeostasis
Homeostasis: state of dynamic equilibrium
e.g. regulation of body temperature, blood pH, glucose levels
Stressors shift our body away from homeostasis
can be physiological, psychological, or environmental
General Adaptation Syndrome: how our body
responds to stress
Eustress is positive stress and promotes high-level
functioning
Distress is negative stress and decreases
performance

57
Q

Sleep

A

Most adults need 7-9 hours of sleep each night to
stay healthy and perform optimally
Sleep is an active and dynamic state; individuals
cycle between REM (dreaming) and non-REM
states several times per night
Non-REM sleep occurs in successive stages
Sleep is important for:
1. clearing the brain of wastes
2. learning and memory
3. proper immune function

58
Q

Ways to minimize stress

A
Ensure you have a support system
2. Improve you communication skills
3. Be kind and nurturing to others
4. Develop healthy exercise, eating 
and sleeping habits
5. Develop healthy coping techniques 
(e.g. meditation, music) 
6. Learn to identify and moderate 
stressors and develop resilience
59
Q

What are the characteristics of addiction

A
Reinforcement
Compulsion or craving
Loss of control
Escalation
Negative consequences
60
Q

What are the types of addictive behaviour

A
Substance use 
disorder 
Gambling disorder
Social media disorder
Gaming disorder
Compulsive buying or 
shopping
Work addiction
Compulsive exercise
Sex addiction
61
Q

What are the routes of administration

A

Injecting/smoking drugs is more likely to
cause dependence
Strong stimulus-response pairing
They wear off more quickly
Users may take more frequent doses
Injecting drugs is more likely to transmit
infectious diseases such as hepatitis and HIV
Smoking drugs can damage the air passages

See table in slides

62
Q

How do drugs affect the brain

A
Changes in brain 
chemistry
Altered effects of 
neurotransmitters
Some increase the 
effects of dopamine in 
pleasure pathway
Nicotine, cocaine, 
alcohol, heroin and 
amphetamines all 
affect dopamine levels
63
Q

Ehat factors influence drug effects

A

Pharmacological properties (e.g. composition)
Dose-response function (e.g. intensity)
Time-action function (e.g. lag time)
Drug use history (e.g. first time or not)
Route of administration (e.g. oral or injection)
Physical factors (e.g. weight)
Psychological factors (e.g. setting)

64
Q

Stimulants

A
CNS stimulants speed 
up the activity of the 
nervous and/or 
muscular system
Some examples include:
Caffeine
Nicotine
Cocaine
Amphetamines
Ecstasy
Ritalin
65
Q

Caffine

A
Most popular psychoactive drug
Coffee, tea, cocoa, energy drinks
Mild stimulant, effects at low 
doses are relatively harmless
Excess consumption can 
cause shaking, difficulty 
concentrating, insomnia, and 
irregular heartbeat
Withdrawal can cause 
irritability, drowsiness and 
headaches
66
Q

Nictone

A
Stimulant drug in cigarettes and e-cigs
Tobacco use is the leading preventable 
cause of disease, disability and death
Smoking is strongly associated with 
CVD and lung cancer
Carcinogens in cigarette smoke 
damage DNA, and poisons weaken 
tumor fighters
Chronic smoking can also cause 
bronchitis, emphysema and 
reproductive complications
If you quit before age 30, health can 
become close to that of a non-smoker
67
Q

E cigs and vaping

A
Uses a mouthpiece, heating 
element, battery and liquid
Not yet known to be safer 
than traditional cigarettes
Vapour still may contain 
harmful chemicals or unsafe 
levels of nicotine (currently 
unregulated)
May help with quitting smoking, 
may also perpetuate addiction
WHO does not recommend 
use until studies determ
68
Q

Cocaine

A
Potent CNS stimulant
Derived from coca plant
Rapid heart/breathing rate, 
decreased appetite
Users may experience feelings of 
euphoria, alertness, competency, 
power, invincibility
reward 
pathway (dopamine)
Short lasting and ends abruptly
Repeated use can lead to insomnia, 
weight loss, impotence
Overdose can cause death due to 
heart irregularities
“ crack” a less pure freebase form
69
Q

Amphetamines

A
Powerful stimulants; effects similar 
to cocaine; highly addictive 
Methamphetamine; 
Can be made from household 
ingredients, therefore cheap
Cause high levels of dopamine
Promote tolerance, powerfully 
addictive, very high relapse rate
Chronic use may lead to severe 
weight loss, heart attack, stroke, 
paranoia, psychosis, violent behavior.
Amphetamine psychosis: psychotic 
features including paranoia, visual 
and auditory hallucinations, and 
delusions
70
Q

Mdma ecstasy

A
X", "molly"; stimulant and mild 
hallucinogen 
Mood elevator (increases serotonin)
Euphoria, increased energy, 
heightened sense of belonging
oming down' associated with 
serotonin imbalances, promoting 
depression
In a club/rave setting can produce 
dangerously high body temperature 
and potentially fatal dehydration 
Especially dangerous when tolerance 
develops and user to take drug at a 
higher dose or mix with other drugs
71
Q

Hallucinogens

A
A group of psychoactive drugs that 
alter perceptions (e.g. visual, 
auditory), feelings and thoughts. 
Some examples include:
) 
MDMA (primarily a stimulant)
DMT
Ketamine
PCP
LSD
Psilocybin
Generally, less addictive
72
Q

LSD PCP PSILOCYBIN

A

LSD PCP (angel dust); psilocybin (magic mushrooms)
are hallucinogens
These drugs alter perception, feelings and/or thoughts
Typically ingested, effects last ~8+ hrs
Risks of irrational acts while on the drug; LSD users may
experience flashbacks
Tolerance develops, but with little physical dependence or
withdrawal symptoms (generally not addictive)

73
Q

Opioids

A
Opioids are a class of drugs that relieve 
pain, cause drowsiness and euphoria
Opium, heroin, methadone, morphine, 
codeine, Demerol, oxycodone, fentanyl
Derivatives or synthetic analogues opium 
from the opium poppy
Some prescribed for pain but most are 
powerfully addictive 
Relaxation, euphoria, slowed breathing,
slurred speech, impaired balance
Higher doses can cause stupor, 
unconsciousness, coma and death
Ongoing opioid (fentanyl) crisis in BC
Naloxone can reverse effects
74
Q

Cannabis

A

Can be classified as a CNS depressant,
hallucinogen or stimulant (various effects)
45% of Canadians have tried cannabis (use
is legal in Canada, see pg. 635)
Active compound (THC) acts on
cannabinoid receptors
Acute effects: mild euphoria, heightened
perception, drowsiness, red eyes
Chronic effects:
May interfere with memory/learning
Associated with reproductive dysfunction
May promote schizophrenia in those susceptible,
especially if used during adolescence
Biggest health risk is effects on airways
Marijuana smoke contains carcinogens

75
Q

Benifits of cannabis

A

May relieve nausea, vomiting, chronic pain
May help treat glaucoma, epilepsy,
anorexia, MS, arthritis and migraines
Safest way to consume is probably
ingestion or with a vaporizer; smoking
joints is probably the most harmful
Recreational marijuana use is now legal in
Canada; logistics of sales and approving
business licences is ongoing

76
Q

Alchohol

A
Alcohol is a CNS
depressant, though it 
may initially feel like a 
stimulant
Most highly abused
psychoactive substance
Acute effects include 
mild euphoria, relaxation, 
altered judgement, 
impaired motor skills
Binge drinking and/or 
chronic use associated 
with many health risks
77
Q

Alcohol absorption

A
Alcohol is not digested, it is 
absorbed directly into the blood 
through the stomach or small 
intestinal wall
Several factors influence the 
rate of alcohol absorption and 
metabolism:
Sex (Male vs Female)
Size (Weight ad BMI)
Fruit sugar
Food in stomach, especially 
fats
Liver enzyme activity
78
Q

Short term risks of alcohol

A

Alcohol affects judgement and changes mood
Consumption (especially to excess) can result in:
memory loss
decreased blood sugar levels; flushing, sweating;
indigestion
slurred speech, blurred vision, impaired motor skills
impaired sexual function
increased likelihood of riskier behaviours, violence,
suicide
increased urine output and dehydration
hangover; withdrawal symptoms
alcohol poisoning; in extreme cases, death

79
Q

Long term risks of alchohol

A
Addiction
CVD
Cirrhosis of the liver
Cancers
Malnutrition
Mental illness
Brain damage
Impaired
immune 
function
Negative social effects
Reproductive effects 
(impotence, infertility)
Fetal alcohol syndrome
(in offspring)
Increased chances of
harm to ones self and 
others (e.g. riskier 
behaviours, accidents, 
violence, suicide)
80
Q

How many people will get and die from cancer

A

Men

45 get
29 did

Women
42 get
24 die

81
Q

Describe the basic biology of cancer

A

Cancer is the abnormal uncontrolled multiplication of cells due to
genetic (DNA) mutations that disrupt the cell cycle
Abnormal cells continue to divide and create other abnormal cells
Eventually, this forms neoplasms (tumours) that can spread
Tumours can be benign (does not spread) or malignant
(spreads and can be life threatening)
Malignant tumour cells can invade blood or lymphatic vessels
and spread to distant sites and produce secondary tumors; this
is called cancer metastasis
Death can occur when cancer affects a major organ or system in
the body (e.g. lungs) to the point where organ function is
significantly compromised
Different types of treatment may be effective

82
Q

How can cancer damage the body

A

Tumours, whether benign or malignant, can block a
blood vessel, compromise a nerve, or otherwise
interfere with normal body function
Immune system cancers can leave the body more
vulnerable to negative effects of infection
Blood cancers (e.g. leukemia) do not produce tumours
but have the same fundamental property of
uncontrolled multiplication
Advanced tumours have a blood supply and can use up
supplies of energy and nutrients meant for healthy cells
They can also metastasize from their original tissue to
another area of the body, compromising function

83
Q

What are the main types of cancer and their incidence in each sex

A
Skin (non-malignant, nearly 
all cured; so not included)
Breast (#1 incidence F)
Prostate (#1 incidence M)
Lung, bronchi (#2 F; #3 M)
Colorectal (#2 M; #3F)
Uterine, cervical, ovarian (F)
Bladder (M)
84
Q

Describe skin cancer

A
Most are carcinomas; grow slowly, 
easy to treat
Malignant melanoma is the rarest
but most deadly form of skin cancer
Risk factors include:
Fair skin and hair, light eyes
Tendency to develop freckles and 
burn in the sun
History of childhood sunburn or intense 
sun exposure
Family history of melanoma
Large number of moles (200+; 50+ if 
< age 20) or atypical moles
Melanoma is 20x more common in 
light-skinned (i.e. white) individuals 
Complete the Sun Sensitivity Test!
Key point: Use sunscreen, even when 
lighter skin tone
85
Q

Describe breast cancer

A
Risk factors: age, genetics, age at
onset of menstruation (menarche)
Lifetime exposure to estrogen
Most common cancer in females (after 
non-malignant skin cancer)
If caught early, survival rate >80%
Dangerous when it metastasizes 
(e.g. via lymph nodes close to the
breasts) forming secondary tumours
Screening: mammograms
Treatment: surgery, radiation, 
chemotherapy, others
86
Q

Describe surgical removal of cancer

A
Some localized cancers can be 
removed by surgery
Surgical excision is the oldest 
type of cancer treatment, and is 
effective against many types
In surgical treatment of breast 
cancer, often, the tumour and 
adjacent lymph nodes are 
removed (e.g. lumpectomy, 
mastectomy)
87
Q

Describe lung cancer

A
Leading mortal cancer in Canada
Smoking is the #1 risk factor; followed 
by second hand smoke, asbestos,
pollution
5-year survival rate < 20%
No effective screening
stages
Typically caught too late (usually by 
CT scanning or x-ray)
Treatment is difficult even in early 
stages
Risk for non-smokers is 5-10% that of
smokers
88
Q

Describe prostate cancer (males)

A
Walnut-sized gland 
near the bladder
Secretes fluid that 
becomes part of semen
Most common cancer 
in males (after non-
malignant skin cancer)
Like breast cancer, 
becomes deadly when 
it spreads
If detected early, 
~95% survival rate
Often has no symptoms
Risk factors: age, obesity, 
physical inactivity, history of STIs;
(possibly) diets with excess 
animal fats, low plant matter
Common symptom: changes in 
urinary frequency or flow
Regular screening age >50
Screening methods:
Digital rectal exam
Prostate-specific antigen test
Treatment options: 
surgery to remove prostate
radiation, cryotherapy, drugs
89
Q

Describe collorectal cancer

A

Begins with polyps, which may progress
through several stages and become
cancerous.
Screening: endoscopy

Starts with the formation of non-cancerous growths called
polyps in the intestine
Risk factors include older age, male sex, inflammatory
bowel disease and family history; obesity, smoking,
alcohol abuse, red/processed meats may increase risk
Symptoms may include:
Change in bowel movements
Pain/tenderness in abdomen
Blood in feces
Can be detected with endoscopic techniques such as
colonoscopy and sigmoidoscopy
Fecal blood screening is recommended (age >50)

90
Q

Describe cervical cancer (females)

A
The cervix is between the 
uterus and the vagina
The leading risk factor for 
cervical cancer is human 
papilloma virus (HPV)
HPV vaccine (Gardasil®) 
helps prevent infection
First indicated for 
females aged 9-26
As of September 2017, 
males aged 9-26 as well
Screening: regular Pap
tests aid early detection of 
pre-cancerous cells 

HPV causes virtually all cervical cancers
Transmitted by skin-skin contact (not just sexual intercourse)
Condoms NOT as effective in preventing transmission
There are many types of HPV
High-risk types cause cancer
Low-risk types cause plantar warts and genital warts
HPV is endemic in human populations
If you are sexually active, you will be exposed to HPV
Females should have Pap tests once they are sexually active
An early detection method that detects pre-cancerous lesions
HPV vaccines only protect against some types of HPV
Vaccinated females still need to have Pap tests
Vaccination BEFORE sexual experience is key
Current B.C. schedule mandates first HPV vaccination at age 11
both females and males

91
Q

Describe cancer prevention strategies

A

Half of cancers can be prevented
~ 80% of cancers are caused by environmental factors
Primary prevention (personal level):
-hand smoke
Reduce exposure to carcinogens
e.g., UV light, radiation, asbestos, acrylamide
Cancer-smart nutrition
-rich fruits & vegetables (e.g., vitamin C, D,
folate); reduce foods; limit
alcohol intake; keep a healthy weight
Receive available vaccinations (e.g. HPV)
Get screenings for early detection (secondary prevention)

92
Q

How do u detect cancer early

A

Screening involves general examinations (e.g.
mammography) done on apparently healthy populations
to identify those who may potentially have a disease
Testing is done on those who are believed to have a
disease. It involves more specific tests (e.g. biopsies/
microscopic examinations) to more thoroughly identify
the presence of a disease (cancer, or otherwise)
A biopsy involves removal of tissue that is suspected
to be diseased for further examination
Testing is more invasive, time consuming, and costly
to test an entire
population for any disease, cancer or otherwise.

93
Q

What are the possible treatments of cancer

A
  1. Surgical removal
  2. Chemotherapy
  3. Radiation therapy
  4. Immunotherapy
  5. Gene therapy
  6. Hormone therapy
94
Q

What is chemotherapy

A
Use of drugs to target and kill 
cancer cells
An option when cancer may 
have spread
Traditional drugs work by
targeting cells that are rapidly
dividing
Affects not only cancer cells but 
normal body cells that tend to 
divide more often (hair follicles, 
lining of stomach and intestine)
Such drugs can cause hair 
loss, fatigue and nausea
95
Q

What is radiation therapy

A
Useful for localized tumors
Beams are focused from several 
directions resulting in a higher 
dose at the tumour to kill cancer 
cells
Radiation damages DNA
Can also kill healthy cells, 
leading to side effects
Often used in combination with 
surgery or chemotherapy
96
Q

What is immunotherapy

A
Stimulating the immune 
system with drugs
Giving immune system 
components (e.g. antibodies)
Cancer vaccines:
Prevention: effective for cancers 
caused by an infection (e.g. HPV,
HepB)
Treatment: effective against some 
cancers (e.g. prostate); boost immune 
system in those already diagnosed with 
cancer
97
Q

What is hormone therapy

A
Effective against cancers 
that are helped by 
hormones (e.g. breast,
prostate, ovarian cancer)
Drugs that block hormone 
receptors or lower 
hormone levels
e.g. drugs that block 
estrogen receptors or 
lower estrogen levels
98
Q

What is gene therapy

A
Modifying the genetic 
material of cancer cells
Modifying genetic 
material of immune cells
Use of altered viruses to 
deliver genetic material
99
Q

What is the most easily way to calculate body weight

100
Q

What percentage of people are overweight in canada

101
Q

What are the risks of excess body fat

A

Increase risk of CVD and diabetes and cancers

Decreases in kidney and gallbladder

Joint and bone disorders

Incontinence and physc risks

102
Q

What are the two shapes

A

Apple (android)

Pear (gynoid)

103
Q

What are the causes of obesity

A
Food consumption
Food production 
Physiology
Individual physical actuvity
Evnvironmental ohycial activity 
Individual physcology
Social physcology
104
Q

What are the dangers of obesity

A
Stroke 
Heart disease
Cancer 
Diabetes 
Hyperstension
High blood cholesterol 
Psychological disorders
105
Q

What is ideal weight

A

The weight at which ones health risk is the lowest
Lifestyle should play a big role
YOU SHOULD LIKE YOUR LIFE

106
Q

Are fad diets good? Why?

A

No. Because they are unsestainable

107
Q

What are the gudilines for sound weight control

A

Sensible diet
Change eating habits
Psychological modification
Physical activity

108
Q

Describe a sensible diet

A

Eat nuttricious dense foods
Fruits and veggies
Reduce chaloric intake… if thats your goal

109
Q

Describe change in eating habits

A
Use smaller plates 
Eat slow 
Wait before earing more 
Leave tempting foods out of sight 
Avoid shopping while eating 
Avoid mindless eating
110
Q

Explain psychological modification

A

Believe in ability to change
Change relationship with food
Challenge negative patterns and thought
Support is key

111
Q

Describe physical activity

A

Increase basal metabolic rate
Maintain muscle mass and reduce fat mass
Promote self esteem
Regularity is key

112
Q

What are the two main eating disorders and describe them

A

Anorexia nevosa
does not eat enough
Leads to amenorrhea intolerant to cold, low BP, CV AND GI, endocrine and skeletal disorders

Bulimia nervosa

Binge eating followed by vomiting or laxitives

Risks: eroision in tooth enamel, damage to esophagus distrubed salt balance, kidney liver snd heart damage and depression