Midterm 1 Flashcards
Alanine 3 letter and 1 letter code
Ala
A
Alanine structure
Ala
A
Glycine 3 and 1
Gly
G
Valine 3 and 1
Val
V
Leucine 3 and 1
Leu
L
Isoleucine 3 and 1
Ile
I
Methionine 3 and 1
Met
M
Proline 3 and 1
Pro
P
Phenylalanine 3 and 1
Phe
F
Tryptophan 3 and 1
Trp
W
Serine 3 and 1
Ser
S
Glycine st
Gly
Valine st
Val
Leucine st
Leu
Isoleucine st
Ile
Methionine st
Met
Proline st
Pro
Phenylalanine st
Phe
Trp st
Trp
Ser st
Ser
Threonine 3 and 1
Thr
T
Threonine structure
Thr
Asparagine 3 and 1
Asn
N
Asparagine structure
Asn
Glutamine 3 and 1
Gln
Q
Glutamine sturcture
Gln
Tyrosine 3 and 1
Tyr
Y
Tyrosine structure
Tyr
Cysteine 3 and 1
Cys
C
Cysteine structure
Cys
Lysine 3 and 1
Lys
K
Lysine structure
Lys
Arginine 3 and 1
Arg
R
Arginine structure
Arg
Histidine 3 and 1
His
H
Aspartic acid 3 and 1
Asp
D
Aspartic acid structure
Asp
Glutamic acid 3 and 1
Glu
E
Glutamic acid structure
Glu
Basic amino acids
Lys, Arg, HIs
Acidic aa
Asp Glu
How are acidic and basic aa classified?
Based on whether the neutral form is an acid or a base
1 Dal =
1/12 of mass of 12C
therefore equals 1 g/mol
Determining L and D configuration
with H pointing towards you,
L form Co R N is in clockwise direction
D form is in counterclockwise direction
Henderson Hassel back
pH= pKa+ log ( base/ acid)
non polar aa
G, A , V, I < L , M, F, W, P
polar no charge aa
G, Y, S, T, N Q, C, H
cys can form disulphide bridges in
oxidative environments
in reducing environments in the cytoplasm, the cys does not form disulpide bridges
pH less than pKa
remains in the protonated form
pH= pKa
half and half of protonated and deprotonated form
pH> pKa
mostly in deprotonated form
pI
pH at which the molecule is neutral