Midterm 1 Flashcards

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1
Q

Nature of Science

A

Does not equal collecting facts
“To do science is to search for repeated patterns, not simply to accumulate facts (general principles)

Two approaches:

  • induction based science (discovery science)
  • hypothesis-based science
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2
Q

Induction-Based Science

A

Inductive/Logical reasoning

Look for patterns -> make predictions about things

Ex. Cell theory - generalities about cells
Ex. Sun rose in the east yesterday and will rise in the east tomorrow

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3
Q

Hypothesis-Based Science

A

Deductive reasoning

Ex. Jill was at pats game 8:00 Tuesday, jack was at pats game 8:00 Tuesday, therefore jack and Jill were at the same game

Hypothesis (s) - Hypotheses (pl)
-> MUST be testable

Ex. Algae, some species can change. Hypothesis: spiky cell shape = anti-herbivore defence. Use a beaker with added herbivores to either disprove or support your hypotheses. If all stay round reject the hypothesis and make a new one. If the round turn spikey it doesn’t prove the hypothesis but supports it (may be other explanation such as turbulence - keep testing)

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4
Q

Scientific Method

A

Hypothetical-deductive method (hypothesis - must be testable - and deductive reasoning)

Design an experiment -> get outcome -> predictable if hypothesis is correct

Hypothesis -? Experiments - outcome is predictable -> tabulate results
If not as predicted -> falsified hypothesis -> need a new one
If as predicted -> support for hypothesis -> more experiments

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5
Q

Theories

A

Theory of relativity:
Hypotheses that attempt to explain a lot
-great explanatory power

For theories to be accepted you need lots of evidence

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6
Q

Occam’s Razor

A

Principle of logic

If several explanations are compatible with evidence at hand the simplest should be the one considered the most probable

Explanations shouldn’t be more complicated than necessary

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7
Q

Atoms

A

Basic unit of matter

2+ atoms held together -> molecule

Different types -> elements

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8
Q

Electro negativity (EN)

A

Property of an atom

Affinity for electrons

Bond between atoms of identical EN=equally shared e-‘s = non-polar covalent with no partial charges (same EN or almost the same EN)

Bond between atoms of slightly differing EN = unequal sharing of e-‘s, partial charges and a polar covalent bond (higher EN gets partial negative charge)

Important: O-H, N-H, O-C, N-C

Bond between very different EN atoms = ionic bond, no e- sharing, higher EN atom takes e- from lower EN atom (ex. Salts)

Non-polar covalent –> polar covalent –> ionic bonds
0 ——— difference in EN ———> big

Strong bonds

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9
Q

Hydrogen bonds

A

Weak bonds

  • transient bond (constantly breaking and re-forming)
  • consequence of polar-covalent bonds containing H (H20)
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10
Q

Water

A

Fundamental to life

Organism are mostly H2O (70-90%)

Biochemistry takes place in aqueous environment

H bonds- lead to water being liquid at room temp as opposed to a gas

Cohesion: Water sticks to itself (ex. Plants pulls water up it)
Adhesion: attracted to solid surfaces that have partial or full charges (ex. Meniscus reading)

Solvent of life (not universal, good for salts(ions) or smallish polar molecules)

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11
Q

Starch

A

Composed of glucose molecules - linked

Attracts water (polar)

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12
Q

Hydrophilic vs Hydrophobic

A

“Water liking” vs. “Water fearing”

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13
Q

PH

A

Measure of acidity

Lower = more acidic
Higher=more basic
7 = neutral

High [H+]=very acidic

Cellular pH is buffered - metabolism is pH dependent (normal cellular pH is 7-7.4)

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14
Q

Carbon Chemistry

A

C - basis of metabolism - transformations of C-based molecules

Cell structure-molecules in a cell are C bases

Most biological molecules are C based (other stuff attached such as H, O, P and S)

“Lego block” - always has 4 bonds - both non polar or polar covalent bonds

Non-polar: C-C, C-H. Polar: C-O, C-N

Show isomerism

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15
Q

Isomerism

A

Molecules with same molecular formula but different structures

Structural isomers: variation in linkages around C atoms

Geometric isomers( Cis/Trans isomers) = variation around a double bond (double bonds don’t rotate)

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16
Q

Enantiomers

A

Mirror images of each other

Variation in arrangement around a chiral/asymmetric C (C with 4 different things attached)

Ex. Amino acid serine

17
Q

Large Biological Molecules

A

Subunits=monomers

Carbohydrates -monomer ex. Glucose

100’s-1000’s of bonded (linked) glucose molecules
-starch, glycogen, cellulose (macromolecules

Lipids not considered to be macro -> considered large biological

40-50 types of monomers per cell time (monomers are C based)

String together many monomers=polymer (need chemical bonds between them produced by condensation reactions = dehydration reactions - removal of H20) - lots of rounds to make macromolecule - reactions tightly regulated by cell

18
Q

Enzymes

A

Proteins that catalyze biochemical reactions

Cells also break down large b=molecules

Hydrolysis -> break apart using water (tightly regulated by cell)
-enzymes responsible for this

Monomers -> polymers -> monomers (recycle monomers to build other polymers)

Energy metabolism