Midterm 1 Flashcards

1
Q

diffusion potential is caused by an _________ concentration difference on the two sides of the membrane

A

ion

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2
Q

extracellular fluid

A

large amounts of sodium and calcium but small amounts of potassium (opposite for intracellular fluid)

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3
Q

cell membrane consists of

A

lipid bilayer, protein molecules

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4
Q

penetrating proteins can constitute as ____

A

transport proteins

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5
Q

some proteins have watery spaces that allow for

A

free movement of water and ions and molecules

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6
Q

carrier proteins

A

bind with molecules or ions to be transported

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7
Q

transport through the cell membrane 2 ways

A

through the lipid bilayer or though the proteins

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8
Q

simple diffusion

A

ion movement across the membrane (lipid soluble or a protein channel with varying levels of specificity)

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9
Q

facilitated diffusion

A

ion movement that requires interaction with a protein to move across the membrane.

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10
Q

active transport

A

ion movement across membrane that requires interaction with a protein and energy

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11
Q

what properties of an ion or molecule impacts their ability to diffuse or be transported across the membrane

A

charge, size, shape, concentration gradient, membrane potential

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12
Q

what circumstance utilized active transport?

A

movement against a gradient

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13
Q

membrane potential

A

electrical difference when comparing the outside and inside of the cell membrane

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14
Q

lipid solubility

A

how fast a substance diffuses through the membrane

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15
Q

the rate of diffusion is directly proportional to its _____

A

lipid solubility

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16
Q

post synaptic integration

A

spatial + temporal summation

17
Q

what maintains the two ion concentration gradients and helps produce the negative membrane potential in neurons?

A

Na+. K+ ATPase pump (but requires energy)

18
Q

what is important for ion movement in neuronal cell membranes?

A

leak channels, Na+. K+ ATPase pump, voltage gates channels, chemically gated ligand channels

19
Q

membrane potential rises high enough to block further net diffusion of sodium ions to the inside

A

j

20
Q

what creates a membrane potential?

A

a concentration difference of ions across a selectively permeable membrane

21
Q

Nernst Potential

A

the voltage required to create equilibrium for an ion with a concentration difference across a membrane

22
Q

example

A

if the electrical membrane potential inside the cell membrane is -94 mV, the electrical gradients would be strong enough to oppose the concentration gradient and prevent K+ ions from diffusing out of the cell

23
Q

neurons have ? to maintain a concentration gradient?

A

Na+. K+ ATPase pump, and K+ leak channels