MIDTERM 03 - Dispensing Process Flashcards
2 examples of medications that interact with each other (PN)
Phosphodiesterase type 5 inhibitor (PDE5) and Nitrates
3 examples of nitrates (NII)
Nitroglycerin, ISMN, ISDN
Refers to situations where one drug affects the pharmacokinetics and pharmacodynamics of another drug when both are administered together
Drug-drug interaction
2 types of drug-drug interaction (PP)
Pharmacokinetic, Pharmacodynamic
Affects the absorption, distribution, metabolism, and excretion of drugs (Types of drug-drug interactions)
Pharmacokinetic interactions
Meaning of ADME (Pharmacokinetic interactions)
Absorption, Distribution, Metabolism, Excretion
Occurs when two drugs have the following interactions: potentiation, antagonism, synergism, and addition (Types of drug-drug interactions)
Pharmacodynamic interactions
Meaning of PASA (Pharmacodynamic interactions)
Potentiation, Antagonism, Synergism, Addition
The combined effect of two drugs is equal to the sum of their individual effects (1+1=2) (Pharmacodynamic interactions)
Addition interaction
One drug reduces or counteracts the effect of another drug; mostly used for toxicity/poisoning interactions (1+1=0) (Pharmacodynamic interactions)
Antagonistic interaction
The combined effect of two drugs is greater than the sum of their individual effects (1+1=>2) (Pharmacodynamic interactions)
Synergism interaction
One drug enhances the effect of another drug that has little or no effect on its own (1+0=2) (Pharmacodynamic interactions)
Potentiation interaction
Interaction of benzodiazepines and 1st generation antihistamines can lead to __________ (Example of addition reaction)
Increased sedation
Example of benzodiazepine
Diazepam
Example of 1st generation antihistamine
Diphenhydramine
Interaction of angiotensin II receptor blocker subtype 1 and calcium channel blockers can lead to __________ (Example of addition reaction)
Greater blood pressure lowering
Example of angiotensin II receptor blocker subtype 1
Losartan
Example of calcium channel blocker
Amlodipine
Interaction of ibuprofen and naproxen can lead to __________ (Example of addition reaction)
Greater anti-inflammatory effect
2 examples of ibuprofen (MA)
Medicol advance, Advil
2 examples of naproxen (FS)
Flanax, Skelan
Interaction of heparin and protamin sulfate can __________ (Examples of antagonistic interaction)
Avoid severe GI bleeding
Interaction between benzodiazepines and flumazenil can __________ (Examples of antagonistic interaction)
Treat benzodiazepine overdose
Interaction of naloxone/naltrexone and morphine, codeine, and heroin can __________ (Examples of antagonistic interaction)
Treat opioid addiction/toxicity
Interaction of sulfamethoxazole and trimethoprim can increase __________ (Examples of synergic interaction)
Antibacterial effect
Interaction of pyrimethamine and sulfadoxine can increase __________ (Examples of synergic interaction)
Antimalarial effect
A combination medication of sulfadoxine and pyrimethamine used for treating malaria
Fansidar
Carbidopa prevents conversion of __________ to dopamine outside the brain enhancing its efficacy (Potentiation inteaction)
Levodopa
__________ prevents conversion of Levodopa to dopamine outside the brain enhancing its efficacy (Potentiation interaction)
Carbidopa
Interaction of amoxicillin and clavulanic acid can increase __________ and __________
Effectivity, Half-life
Combination medication of Amoxicillin + Clavulanic acid
Co-amoxiclav (BN: Augmentin)
Interaction between ampicillin and sulbactam can increase __________ and __________
Effectivity, Half-life
Brand name of the combination medication of Ampicillin and Sulbactam
Unasyn
Interaction of Piperacillin and Tazobactam can increase __________ and __________
Effectivity, Half-life
Brand name of the combination medication of Piperacillin and Tazobactam
Piptaz
This law governs the Philippine practice of pharmacy and states that dispensing is an exclusive task/right of a registered pharmacist
R.A. 10918 (Philippine Pharmacy Act)
This law mandates the protection of personal information; pharmacists must ensure that patient records are kept confidential
R.A. 10173 (Data Privacy Act of 2012)
This law mandates discounts for senior citizens on medications and medical equipment
R.A. 9994 (Expanded Senior Citizens Act of 2010)
R.A. 9994 grants __________ percent discount and exemption from the value added tax (VAT)
20%
4 requirements of avail privileges and discounts (VPOA)
Valid and updated prescription, Purchase slip booklet, OSCA identification card, Authorization letter
This law states that every pharmacist dealing in dangerous drugs or controlled precursors and essential chemicals shall maintain an original record of sales, purchases, acquisitions, and deliveries of dangerous drugs
R.A. 9165 (Comprehensive Dangerous Drugs Act of 2002)
This law ensures that pharmacists stay updated with the latest advancements in pharmacology, therapeutics, and pharmacy practice
R.A. 10912 (Continuing Professional Development (CPD) Act of 2016)
For “loose” tablets, attach a __________ that contains the phrase “For internal use only”
White colored label
For compounded medications such as ointments and creams, attach a __________ that contains the phrase “For external use only”
Red colored label
Helps identify and prevent dispensing errors such as incorrect dosages, wrong medications, or mislabeling
Counter-checking
Is essential for achieving the desired therapeutic outcomes
Accurate dispensing
This concept entails dispensing the drug with the correct generic name, brand name, dosage form, and strength
Right drug
This concept entails confirming if the medication to be dispensed is being provided to the right patient
Right patients
This concept entails making sure that the drugs to be dispensed are labeled of the correct time
Right time