Mid-Semester Flashcards
(110 cards)
What is the atomic number?
Number of protons
What is the mass number?
Protons + neutrons
What are isotopes?
Atoms of the same element with different numbers of neutrons
What are photons?
no mass or electrical charge - pure energy
What are 2 types of radiation?
Waves -> light, x rays or gamma rays represented by photons or quanta
Particles -> alpha or beta particles - travel slower than waves
Alpha particles like helium nuclei
Beta particles like electrons/positrons
What is radioactive decay?
spontaneous radioactive disintegration of an atomic nucleus resulting in the release of energy -> radiation
Emissions from the unstable nucleus can be in the form of particle (alpha/beta) or electromagnetic (wave) radiation
What is electromagnetic radiation?
Visible light, radio, gamma and x rays
Move at speed of light in straight line
Different forms distinguished by wavelength and frequency - smaller the wavelength the higher the frequency (hz) and by amount of energy they transfer
What are 2 types of radiation in electromagnetic spectrum?
- Non-ionising radiation - light, radio and microwave
- Ionizing radiation - high energy + frequency -> can remove an electron from an atom (x rays and gamma rays) -> ionization is process where atom can gain pos or neg charge by losing electrons (causes DNA damage)
What are 5 types of ionising radiation?
- Alpha particles
- Beta particles
-> these particles are not part of electromagnetic spectrum but carry energy particles, they are not photons like as in electromagnetic radiation
- X and gamma rays
- Cosmic radiaiton
- Neutrons
What are sources of ionizing radiation in vet?
X rays -> radiography, fluoroscopy, radiotherapy, computed tomography (CT)
Gamma rays -> nuclear scintigraphy (bone scans)
When X rays pass through matter what can they do?
- Be absorbed by atoms in subject
- Pass straight through to x ray plate
- Change direction and scatter (30% do this in a normal x ray)
Efects of ionizing radiation on living cells
Creates free radicals in water reacting with DNA to cause damage
Proteins can repair DNA sometimes but if not cell death or permanent mutation occurs
3 classifications of X ray damage to cells
Somatic -> affects physical structure of body and cells change quickly
Genetic -> mutation of genes and inherited abnormalities, some lethal some recessive
Carcinogenic -> affects cell so cancer forms often decades later
What are deterministic or non-stoachastic affects?
Occur when radiation dose is large enough to cause extensive cell death
Severity is proportional to the dose
There is a threshold level of exposure, above which certain affects like radiation burns occur
What are probabilistic or stochastic effects?
Where effects have no threshold level and every exposure increases the risk that disease occurs
“no safe dose” effects - eg sun
What are the most sensitive tissues to ionising radiation?
young animals and feotus -> Organogenesis and rapid growth
Thyroid gland - high metabolic activity
Gut -> rapid proliferation
Skin - squamous or basal cell carcinoma, red dry scaly skin
Bone marrow -> Decrease rbc, platelet and lymphocyte production
gonads -> decrease sex hormones and increase genetic mutations
Eye -> cataracts in the lens
What is the purpose of radiation protection standards?
Understand that it is not possibke to eliminate all radiation exposure but provide system of control to avoid unnecessary exposure and keep doses in low range
What are 3 dose quantities to measure radiation exposure?
Absorbed dose - energy deposited in a kilogram of substance by radiation
Equivalent dose - absorbed dose weighted for harmful effects of different radiation
Effective dose - equivalent dose weighted for susceptibility to harm of different tissues
How do we measure radiation exposure?
Landauer OSL dose badges
Optically stimulated luminescence
Detector is aluminium when stimulated by laser becomes luminescent in proportion to amount of radiation exposure
Wear in centre of chest under lead gown
What is the dose limit for a member of the public and occupationally exposed persons?
Public -1mSv
Us - less than 100mSv over 5 years (20mSv per year) effective dose
Who is responsible for looking after dose exposure?
Practice owner or principal vet
What are 3 questions to ask before taking a radiograph
Justification - benefit the animal and outweight risk + cost of irradiation
Optimisation - use lowest possible exposure to obtain radiograph
Compliance in limits - operators must not exceed max allowed exposure for the year
What are tthe 3 tenets of radiation safety?
Radiation dose determined by amount of:
- Time person is exposed to ionizing radiation
- Distance between person and radioactive substance
- Shielding used to protect person
What are factors involved in radiation protection - time?
Less time in radiography or fluoroscopy rooms
GA animals so no one holds them
No one in room when radiograph taken
Minimise time with patients undergoing nuclear medicine procedures