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transfusion kendel mid 1 > mid 1 > Flashcards

mid 1 Flashcards

1
Q

what is the purpose of the unique ID gievn to the donor

A

traceback

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2
Q

what is examined prior to donation

A

IV drug use armsz

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3
Q

disinfectant

A

2% chlorhexidine gluconate and 70% isopropyl

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4
Q

if allergic to chlorhexidine

A

isopropyl + iodine

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5
Q

which bag does the first blood go into

A

satellite bag

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6
Q

what is done to avoid clotting as blood is taken

A

gentle mixing

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7
Q

how long does blood colelction take place

A

10 min

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8
Q

what is autologous

A

donation to yourself

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9
Q

autologous

normovolemic hemodilution

type of blood
added to what
stored
longevity
our involment

A

whole blood
crystalloid or colloid solution to lower hematocrit
RT
8 hrs
does not involve trnsf med

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10
Q

autologous

intraoperative salvage

what is it
whats done to it
hrs
involment
why is it done

A

collection the blood that you loose during a surgery and putting it back inside

colelcted from the surgical site, the debri HgB and plasma are removed before put back in

6 hrs

not involved

whne preop collection cnt be done

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11
Q

autologous

post operative salvage

colelcted from
processing?
involment

A

from drainige tube
processed or not processed
we may be involved

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12
Q

autologous

long-term storage
how are they prcoessed
sotrage temp
time

3 reasons

A

frozen deglycerolized RBC
frozen
10 years

rare phenotype, Ab to a high incidence Ag, multiple Ab

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13
Q

what must be on the aoutologous label

4 main and 2 side

A

its only for use for this person

name, PHN or DOB, transfusion facility and biohazard label

indications of use which surgery
contraindications: what they have as disease

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14
Q

is pre -op autologous hospital smaples have NAT or syphilis testing done

A

neur

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15
Q

is pre -op autologous CBS samples have NAT or syphilis testing done

A

they have evertyhing done, other than syphilis will cause it to be destroeyd

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16
Q

8 things that donor units are tested for

A

ABO
Rh
Screen
Heb B surface antigen
anti-HIV 1/2
anti hep C
anti TTLV :hep infection w/ T cell lukemia virus type 11
syphillis

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17
Q

choice of anticoagulant and whats in it

A

CPD
citrate, phosphate, dextrose

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18
Q

what is added to extend shelf life

what is it
whats in it
how long does it extend

A

SAGM
saline
adenine
glucose
mannitol

42 days

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19
Q

when is directed donation allowed through CBS

A

parent to child and its advised against

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20
Q

how many weeks apart must the donations be

A

1 week, 4 max

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21
Q

what sticker is put on direct

A

direct use only

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22
Q

what is the family donors blood increase the risk of

A

graft vs host disease

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23
Q

can husbands dinate to wives

A

not recomended especily when she can have kids can make Ab against Ag

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24
Q

what must happen to the blood donations given by relatives

A

irradiated

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25
Q

what is a designated donation
4 reasons for it

can it be corssed over to reg use

A

special donor for special patient

-speicfic type of leukocyte or platelets
-rare blood type
-multiple allo-Ab
-regular transfusions

-only one that can be corssed over to reg use

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26
Q

apheresis donation

what is it

A

take out the blood and take something from it like the plasma, whites, reds, platelets, hemapoietic progenitor cell and then we return the rest back into the patient

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27
Q

when sagm is added and it increases shell life what temp does it have to stay for that 42 days

A

1-6C

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28
Q

RBC temp storage

A

1-6 C

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29
Q

citrate role

A

antigocoagulant, chelates Ca

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30
Q

dextrose job

A

needed for the glycolytic path to make ATP

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31
Q

dosium phosphate

A

buffer, high pH to maintain 2,3 DPG

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32
Q

adenine job

A

substrate to synthesize ATP, impoves viability

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33
Q

manntitol job

A

stabilizing agent, prevents hemolysis

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34
Q

what are storage lesions

A

chemical and physical changes that happen to stored blood

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35
Q

what happens to these as they are stored

pH
atp
2,3 dpg
labiile factors
platelet
leukocyte
potassium

A

all but K decrease, and K goes up

36
Q

what dosent survive in whole blood and must be stored seperately

3 things

A

PLT
WBC
clotting factors

37
Q

how soon after donation must RBC be stored away

A

1 hr

38
Q

how long does it take to harvest platelets

A

8 hrs

39
Q

what must happen to PLT when stored

A

constant agitation

40
Q

PLT storage temp

A

20-24

41
Q

granulocyte temp

A

20-24

42
Q

coagualtion factor storage/ cryoprecipitate

A

-18 or colder

43
Q

how soon can RBC need to come back if not used

A

60 min

44
Q

what must be done to all RBC product

A

leuko reduced

45
Q

what 3 other things can be done to RBC products

A

SAGM, wasehd, deglycerolized

46
Q

goal of RBC -LR-SAGM

3 times when we give and 3 times when we dont

A

increase oxygen carrying capacity

blood loss
chronic anemia
medications that supress bone marrow

dont give to those that can be corrected with drugs
to correct coagualtion probelms
to increase blood suply

47
Q

RBC -LR-SAGM
closed system
vs
open

days and temp

A

42 days 1-6

24 hrs 1-6
4 hrs >7

48
Q

RBC-LR-Washed

what happens

used for 3

not used for

A

washed with isotonic saline 0.9%, removes plasma, potassium, anticoagulants, and up to 25 % RBC , goal is to remove proteins that can cause a rxn

Indications :
IgA deficient patients
neonates to remove K
remove anti-HPA-1 (nocturnal Hgb patients)

dont give to those that can be corrected with drugs
to correct coagualtion probelms
to increase blood suply

49
Q

RBC-LR-Washed

open

days and temp

A

24 hrs 1-6

4 hrs if about 6 (20-24)

50
Q

RBC - LR- Deglycerolized

what is added

2 concentrations and 2 temps

A

cryoprotectant + glycerol bf frozen: protects internaly and externally

40% @ -65, slow to freeze

20%, @-120 fast to freeze

51
Q

Deglycerization

how is it thawed
time to thaw
why is glycerol removed
how is it removed
how many ml in unit
Hct

inidcations: 4

contradictions

A

hot bath
10 min
removed to prevent hemolysis
via a washer
180 mL
0.80 L/L

used for
rare phenotype
multiple Allo-Ab
Ab to high incdence Ag
severe anaphylactic rxn

not used same as rest

52
Q

deglycerized

time storage
temp depends on
once thawed good fro time nd temp
corss match must be done at

A

10 yrs when frozen
temp depends on glycerol content

once thawed
24 hrs at 6
4 hrs if 20-24
corss match at IAT

53
Q

Frozen plasma

from what
seperated by
reduced amounts of factors

A

from whole blood
seperated using a buffy coat
reduced factos 5 and 8

54
Q

if plasma is not LR labeled how much leoco in a bag

A

> 5 x 10^6

55
Q

storage of plasma
frozen vs thawed

A

frozen : -18, 1 yr
thawed: 1-6 120 hrs (5 days)

56
Q

apheresis fresh frozen plasma

how soon must be frozen
what factors are there
is it leko reduced

A

8 hrs
5 and 8
not

57
Q

storage of apherissi FFP

frozen
thawed
sodium citrate thawed

A

-18 or colder 1 yr
1-6 24 hrs
1-6 120 hrs

58
Q

use of the plasma

A

massive hemorage
TTP, HUS
neonatal exchange
emergency

not used for : volume, protiens, factors, IgA patients

59
Q

for plasma is Rh considered

A

neur

60
Q

overwrap bag for plasm

A

for protection from bacteria

61
Q

pooled platelets, used for

A

bleeding, due to PLT disoorder or other episodes, and cancer patietns with low PLT

62
Q

for PLT compatibility is not requreid but

A

blood group must be known

63
Q

apheresis PLT used in

A

refractoriness-HLA matched
similar to pooled

64
Q

storage of pooled PLT / apheresis PLT

closed
open sys

msut be

A

closed
7 days 20-24
4 hrs 20-24 C

agitated

65
Q

refractoriness

3 reasons

A

failure to increase even after 2 transufsions

removed by spleen : DIC
drugs
HLA Ab

msut be compatible but not speicfic

66
Q

when Rh- get Rh+ PLT what must be givn

A

win roh

67
Q

cryoprecipitate

used for / source of

A

thawed and removal of cryo poor plasma

fibrinogen and factor 13

not used for treat hemophilia A, or vWD

68
Q

cyroprecipitate
frozen
thawed / pooled

A

-18C 1 yr
20-24 4 hrs

69
Q

cryoprecipitate

thawed at what temo
NaCl at what %
how many units pooled

A

37 c
.9 %
8-10

70
Q

cryosupernantan plasma, LR

frozen
thawed

A

-18 1 yr
1-6 120 hrs

71
Q

albumin
storage
diff concentrations and what are they used for

A

stored below 30
25%: liver disease

5%: plasma exchange, burns

72
Q

Intravenous immune globulin IVIG

used for

A

used to treat viruses
taken from plasma protein

primary humoral immunodeficeincy
ITP
secondary hypogammaglovulinemia
kawasaki
guillian barre syndrom

73
Q

RhIG

stored and used w/ in

A

from pooled plasma of high anit-D tittre
28 wks, 72 hrs, Rh + PLT
2-8 C

4 hrs after reconstirtuion

74
Q

HBIG
used
store

A

exposure to hep B, 2 wks sexual expos, infants

2-8 C

75
Q

factot 8 and 9

A

from pooled plasma

2-8 c

76
Q

CMV negative RBC

A

used onlly for intta uterine

all blood is filtered and LR and then tested

77
Q

irradiated product

decreased risk of

minimu dose

A

graft vs host in immuno compromised, T lymphs dont attach

prevents T replication

25 Gy to central, 15 Gy to the rest

78
Q

steps to issueing

A

request slip
grab product and inspec
tech issues unti by compiter
then given to worker / porter
blood tag added to unit

79
Q

what is added to / administrated along with a product

A

0.9 % NaCl

80
Q

what should nevr be given together w/ blood

A

anything w/ calcium or gkucose

81
Q

what 2 other products can be gien along with RBC

A

albumin and plasma

82
Q

is the visual inspection documented

A

yah

83
Q

if stoed at X then must be trasnported at y
1-6
20-24

A

1-10
20-24

84
Q
A
85
Q

RBC must be less than how old to be washed

A

2 wks

transfusion kendel mid 1 (1 decks)

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