Microglia

Question 1

_____________ are immune system cells that recognize, engulf and destroy infected, damaged or dead cells.

Answer 1

MACROPHAGES

Question 2

____________ are the resident macrophage (eaters) immune cells of the CNS,

Answer 2

MICROGLIA

Question 3

Microglia facilitate and also coordinate responses between the ____________ immune system and the brain.

Answer 3

PERIPHERAL

Question 4

Cytokines are released by cells and affect the behavior of what?

Answer 4

OTHER CELLS

Question 5

Name the two ways pro and anti-inflammatory cytokines can be transported into the brain?

Answer 5

1. BLOOD (HUMORAL PATHWAY)
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2. VAGUS NERVE (NEURAL PATHWAY)

Question 6

Name the 5 cardinal signs of peripheral inflammation?

Answer 6

PAIN
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HEAT
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REDNESS
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SWELLING
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LOSS OF FUNCTION

Question 7

In situations such as: meningitis, head trauma, or autoimmune diseases of the CNS, what may neuroinflammation resemble?

Answer 7

PERIPHERAL INFLAMMATION

Question 8

What can neuroinflammation be used to identify?

Answer 8

A DIFFERENT EVENT DRIVEN BY MICROGLIAL CELLS

showing few if any of the cardinal signs of peripheral inflammation