microbiology virus 1

Question 0

what kind of immune response is induced by killed/inactivated vaccines?

Answer 0

Humoral response only

Live attenuated creates both humoral and cell mediated response

Question 1

define tropism

Answer 1

infectivity of virus, depends on protein coat

Question 2

Live attenuated vaccines for…

Answer 2

smallpox
yellow fever
chickenpox (VZV)
Sabin's polio virus
MMR
Influenza (intranasal)

Question 3

Killed vaccines for…

Answer 3

Rabies, Influenza (injected), Salk Polio
(RIP)
HAV (Hepatitis A)

Question 4

Recombinant HPV vaccine effective for what types?

Answer 4

6, 11, 16, 18

Question 5

only single stranded DNA virus

Answer 5

parvovirus

Question 6

all RNA virus except ____ are ssRNA

Answer 6

reovirus

Question 7

what kinds of purified nucleic acids from virus genome are infective?

Answer 7

dsDNA (except poxvirus and HBV) and

+)ssRNA (ie mRNA

Question 8

only this kind of virus is diploid

Answer 8

retrovirus (2 identical ssRNA)

Question 9

viral replication:
DNA virus?
RNA virus?

Answer 9

DNA: in nucleus (except poxvirus)
RNA: in cytoplasm (except inlfuenza and retrovirus)

Question 10

Naked nonenveloped viruses

Answer 10

Papillomavirus
Adenovirus
Picornavirus
Polyomavirus
Calcivirus
Parvovirus
Reovirus
Hepevirus

PAPA Calculated Per Rio Hipster

Question 11

all DNA viruses are linear except

Answer 11

papilloma
polyoma
hepadna

Question 12

causative agent for HBV

Answer 12

Hepadnavirus (dsDNA)

Question 13

Symptoms of Adenovirus (dsDNA)

Answer 13

Febrile pharyngitis
pneumonia
conjunctivitis (pink eye)

Question 14

B19 virus also known as

symptoms in children
symptoms in adults

Answer 14

Parvovirus (ssDNA)

children: Slapped cheek rash (erythema infectiosium), hydrops fetalis
adults: RBC aplasia, rheumatoid arthritis like symptoms

Question 15

hydrops fetalis etiology

Answer 15

stems from fetal anemia, where the heart needs to pump more blood to accommodate oxygen demand. Leads to edema subcutaneously, in pleura, in pericardium, or in abdomen. Can be autoimmune response to Rh disease, or non-immune to B19 virus, CMV, syphillis, or anemia.

Question 16

types of HPV that cause warts

Answer 16

1,2,6,11

Question 17

types of HPV that cause cervical cancer

Answer 17

16, 18

Question 18

Polyomavirus: two types, and their symptoms

Answer 18

JC virus: progressive multifocal leukoencephalopathy (PML) in HIV

BK virus: targets kidney in transplant patients

Polytheism until Jesus Christ

Question 19

Most common cause of encephalitis in the US

Answer 19

HSV-1

Question 20

Herpes types that can be spread by respiratory secretions

Answer 20

HSV-1, VZV, EBV

Question 21

VZV latent in what part of body

Answer 21

dorsal root of trigeminal ganglia

Question 22

EBV symptoms

Answer 22

mononucleosis
Burkitt’s/Hodgkin’s lymphoma
nasopharyngeal carcinoma

Question 23

Most common cause of neonatal infections

Answer 23

CMV

Question 24

Lab finding for CMV symptoms of CMV

Answer 24

Owl's eye inclusions congenital infections, mononucleosis, pneumonia, retinitis

Question 25

Tests for HSV

Answer 25

PCR is test of choice Tzanck: smear of skin vesicle to detect multinucleated giant cells commonly found in HSV-1,2 and VZV

Question 26

EBV symptoms latency in where? Also known as? Test for?

Answer 26

fever, hepatosplenomegaly, pharyngitis Infects and latent in B cells aka Kissing Disease Positive Monospot test: agglutination of RBCs