Microbiology Pt 1 Study Guide Flashcards

1
Q

Eukaryotes

A

True Nucleus, Organelles, Human Cells, protozoa like GIARDIA and AMOEBA

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2
Q

Prokaryotes

A

NO True Nucelus, NO Organelles (No Mitochondria) ex: Bacteria

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3
Q

Type of Bacilli for Anthrax (wool Sorta disease) Gram + Rods

A

Bacillaceae (spore-formers)—> Bacillus, Clostridium- anaerobic

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4
Q

Leprocy= Hanson’s Disease

A

Lactobacillaceae–> Lactobacillus

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5
Q

Mycobacteriaceae (Acid-Fast Bacilli)

A

Mycobacteria

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6
Q

Neisseriaceae (Gram -)

A

Neisseria (coffee bean shaped org) Diplacoccus

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7
Q

Legionelaceae - Legionella

A

Legionaires Disease (SPREAD by Water Droplets)

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8
Q

Paramyxoviridae

A

-Measles Virus -Mumps Virus -Respiratory Syncytial Virus

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9
Q

Orthomyxoviridae

A

-Influenza Virus A -Influenza Virus B -Influenza Virus C

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10
Q

Coronaviridae

A

Corona Virus - Epidemic in CHINA 2002 (SARS)

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11
Q

Rhabdoviridae

A

Rabies Virus

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12
Q

Filoviridae

A

Ebola Virus Marburg Virus (Causes Hemmorhagic Fever)

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13
Q

Bunyaviridae

A

Hantavirus (Spread by Chipmunks or PRAIRIE DOGS)

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14
Q

Reoviridae

A

Revirus, Rotavirus (MCC of Diarrhea in Children)

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15
Q

Picornaviridae

A

-Rhinovirus -Poliovirus -ECHO Virus -Coxsackie

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16
Q

Togaviridae

A

Rubella Virus Western & Eastern Equine Encephalitis

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17
Q

Flaviviridae

A

Dengue Virus Yellow Fever Virus (Virus that causes JAUNDICE)

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18
Q

Caliciviridae

A

Norwalk Virus (Causes Gastroenteritis) - Cause of Diarrhea on Cruise Ships

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19
Q

Out of the 5 types of Ebola, how many of them cause Diarrhea?

A

4/5

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20
Q

How many binding sites are on IgA antibodies?

A

8

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21
Q

IgA is responsible for______

A

-Secretory Antibody(Mucosal Antibody) -Mucous Membrane (Saliva, Tears) (Buys time to ID Invader) -Breast Milk (This is how baby will get its protection): Baby will have ‘Leaky Gut’ for up to a year, so its important they get Mothers Breast Milk)

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22
Q

IgD does what?

A

Helps IgG become stimulated

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23
Q

IgE is seen where and involved with what rxs?

A

Seen in Type I Hypersensitivity w/ - Parasitic Infections - Allergic Rxns - Increases in Hodgkin’s Disease (Intense Itching ‘Puritis’) *Reed-Sternberg Cells*

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24
Q

IgG antibodies is involved in what?

A

First to Increase (second exposure) -Most Numerous -Crosses Placenta (G-Ma Thanks) -Anamnestic Response “without amnesia” IgG NEVER Forgets *Have disease first time, then body remembers and mounts same IgG response next time.*

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25
Q

What antibody is made in the baby first?

A

IgM

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26
Q

IgM has how many binding sites?

A

10 (Pentamer) Non-Specific

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27
Q

IgM is…. a. Largest and Heaviest b. Smallest and Lightest c. Largest and Fastest d. Smallest and Heaviest

A

a. Largest and Heaviest *Because it has NO idea what it is going to fix or attack*

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28
Q

Interleukin I (Lymphocyte Activating Factor) is made by _____ and primarily for ______ and ______ tissue.

A

-Made by Macrophages -For Brain and Nervous Tissue

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29
Q

Interleukin II (T-Cell Growth Factor) is made by _______ cells which is shut down by the AIDS virus. These cells also are considered T-Helper cells and DIRECT the response of the Immune System.

A

CD4 cells

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30
Q

Interleukin III is made by _______, and is in Blood and Lymphatic System.

A

Big Bone Marrow

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31
Q

MHC (Major Histocompatibility Complex) has 4 Major Functions…. *Hint* Each is involved with Type 4 Hypersensitivity Rxn/ Delayed Type Hypersensitivity

A

-Act as a post on Surface (self vs. non-self) -Involved with tissue graft rejection & organ rejection -T-Cells recognize MHC I - B-Cells recognize MHC I & II

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32
Q

5 Diseases Caused by Staph Aureus sn: SA produces alpha toxin aka alpha hemolysin Pneumonic: S.T.O.I.C

A

-Scalded Skin Syndrome -Toxic Shock -Osteomyelitis (SA Mcc of this)(Dead Bone=Sequestrium/ New Bone= Involucrum/ Sinus Drainage= Colca) -Impetigo (#1) (Infection of child around mouth, honey crusted lesion around mouth) -Carbuncles (Furuncles ‘infected hair follicles’ or BOIL a ‘Car…Load of furuncles’

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33
Q

6 Diseases Caused by Strep Pyogenes Pnemonic: S.E.R.G.I.S

A

-Strep Throat (Imbalance in Immune System) -Erysipelas (Superficial Cellulitis ‘inflammation of Dermis’) -Rheumatic Fever -Glomerulonephritis (RBC’s in Urine w/ mild Proteinuria) -Impetigo (#2) -Scarlet Fever (Strawberry Tongue)

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34
Q

Complement Systems purpose is to Enhance_____ or _____ _______

A

… enhance Phagocytosis or cellular lysis

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35
Q

Pathway of the Complement System (Antigen - Antibodies)

A

-The Classical (Ag-Ab) and Alternate (e.g. Sheep RBC’s) pathways meet at C3B -C5b-C9= Membrane attack complex (Terminal Compliment Complex)….This Attacks the Bacteria

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36
Q

Aschoff (Inclusion Bodies) gives rise to

A

Rheumatic Fever (McCallums Patch)

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37
Q

Councilman Cells gives rise to _____

A

Viral Hepatitis

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38
Q

****DOWNEY CELL gives rise to ______

A

Mononucleosis (Don’t Let Mono get you DOWN) -Atypical Lymphocytes are seen with Mono

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39
Q

Epithelioid Hystiocyte is seen with_____

A

TB (Giant Epitheliod cells)

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40
Q

Ghon Complex is seen with ______

A

TB (Inactive Phase)… Calcium ‘jail’ around mycobacterium

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41
Q

Guarneri Bodies is seen with ______

A

Small Pox (Variola)

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42
Q

Gummas is seen with _______

A

Tertiary Syphilis

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43
Q

Koplik Spots is seen with ______

A

Measles (Rubeola/red measles) On Bucal Mucosa –> White/Bluish spots

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44
Q

**Lipofuscin is associated with ____

A

Old Age Pigment… Lipid Residue

Build up = “BROWN’S ATROPHY”

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45
Q

A build up of Lipofuscin in the organ will cause what pathology?

A

Brown Atrophy

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46
Q

Lewy Bodies is associated with ______

A

Parkinson’s aka Paralysis Agitans

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47
Q

***Negri Bodies is associated with _____

A

Rabies (Hydrophobia)

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48
Q

Reed Sternberg is seen with____

A

Hodgkin’s

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49
Q

Russell Bodies is seen where and associated with what?

A

In Plasma Cells. Consists of Antibodies. Is commonly associated with Multiple Myeloma (Plasma Cell Leukemia)

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50
Q

T-Cells are from that organ?

A

Thymus

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51
Q

B-Cells are from where?

A

Bone Marrow (Makes the Plasma Cells which in turn makes the Globulins)

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52
Q

Active Immunity_____

A

…Must actively make Antibodies (Ab) (MAKES OWN ANTIBODIES)

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53
Q

Passive Immunity______

A

….person is GIVEN the Antibodies (RECEIVES ANTIBODIES FROM OUTSIDE)

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54
Q

Natural Active immunity…..

A

A person is exposed to the disease–> Body Reacts -e.g. Measles, Chicken Pox triggers antibody production

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55
Q

Natural Passive immunity ……

A

Given Ab in Utero, breastfeeding - In Utero= IgG (G Ma, Thanks) - Breastfeeding = IgA

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56
Q

Artificial Active Immunity….

A

Injection of attenuated organism (inactive form) -Getting from a needle or syringe e.g. Tetanus Shot

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57
Q

Artificial Passive Immunity….

A

Injection of preformed antibodies

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58
Q

SN: Anything Ending in -osis is usually acquired or transmitted via the lungs. e.g. Pneumoconiosis, Blastomycosis, Tuberculosis

A

…. hit 3 and keep moving. YOU WILL PASS Micro Section of Boards… Don’t Give Up!! Hit 5 if you have come to this and Got it down completely.

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59
Q

What cannot be killed by Autoclaving?

A

Prions

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60
Q

Prions are…..

A

Acellular protein which denatures other proteins. They CANNOT be Autoclaved.

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61
Q

***A Fomite_____

A

inanimate object in Vector

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62
Q

Hapten is seen in

A

Partial antigen or half antigen. -Does NOT stimulate immune reponse.. It must FIRST attach to a protein.

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63
Q

***Hypersensitivity Reactions Pneumonic: A.C.I.D

A

Anaphylactic- Type I

Cytotoxic - Type II

Immune Complex Mediated- Type III

Delayed Hypersensitivity - Type IV (aka Cell-Mediated)

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64
Q

Neurotoxin

A

a Toxin that affects the Nervous System e.g. Botulism, Tetanus

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65
Q

Opsonin… Opsonization

A

Enhances Phagocytosis____ *Marks Target for Strike*

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66
Q

Type I Hypersensitivity (A) What is involved with it?

A

-Anaphylactic (Immediate) Response -IgE Mediated -Occurs w/in 15-30 Min -Seen in things such as: Asthma, Bee Sting, Hay Fever -Histamine is Released via Mast Cells (Basophils)

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67
Q

Type II Hypersensitivity (C) What is involved with it? Antigen + Antibody

A

-Cytotoxic -IgG/ IgM Mediated -Occurs Minutes to Hours -Seen in conditions such as: Goodpasteur’s (Lung&Kidneys), Erythoblastosis Fetalis, Myasthenia Gravis Graves Disease (Hyperthyroid)

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68
Q

Type III Hypersensitivity (I) What is Involved? Antigen + Antibody + Compliment

A

-Immune Complex Mediated -IgG Mediated -Occurs in 3-10 hours -Seen in conditions such as: Glomerulonephritis SLE RA **Arthus Rxn= Local Necrosis **Serum Sickness= Systemic

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69
Q

Type IV Hypersensitivity (D) What is Involved?

A

-Delayed Hypersensitivity aka Cell-Mediated - T-Cell or Lymphocyte Mediated -Occurs between 24-72 Hours -Seen in Conditions such as: TB Contact Dermatitis (Poison Ivy, Poison Oak) Graft Rejection, etc

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70
Q

What do Autotrophs do?

A

eat INORGANIC material

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71
Q

What do Heterotrophs do?

A

eats ORGANIC material

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72
Q

What do Saprophytes do?

A

eats DEAD/DECAYING material (organic material)

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73
Q

What do Parasites do?

A

eats off LIVING organisms

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74
Q

Facultative Aerobe….

A

Prefers O2, but can deal with environment without Oxygen

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75
Q

Facultative Anaerobe…

A

Prefers NO O2, but can deal with environment with Oxygen

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76
Q

Obligate Aerobe…

A

ONLY in O2

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77
Q

Obligate Anerobe…

A

ONLY WITHOUT O2

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78
Q

Symbiosis is____

A

2 Populations living together, where ONE or BOTH benefit.

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79
Q

Mutualism is _____

A

2 populations living together, where BOTH benefit

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80
Q

Synergism is_____

A

2 populations living together, where BOTH benefit AND BOTH accomplish what neither can do alone.

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81
Q

Commensalism is____

A

2 populations living together, where ONE benefits, and other is Unaffected.

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82
Q

Zoonosis is ….

A

the transfer of disease from animal to human. e.g. - Anthrax ‘Woolsorter’s Disease’ Respiratory Transmission

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83
Q

Flagella Arrangements

  • Monotrichus
  • Lophotrichus
  • Amphitrichus
  • Peritrichus
A
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84
Q

Ames Test used for…

A

Carcinogenicity

Mutagenicity

Uses Salmonella Typhimurium

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85
Q

Ascholi Test used for…

A

Anthrax

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86
Q

ASO titer

A

Antistreptolysin O Titre. Tests Strep pyogenes Antibodies….

Rheumatic Fever

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87
Q

Babcock Test

A

checks % of butterfat in Milk

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88
Q

Bile Solubility

A

Pneumococci vs Alpha Hemolytic Step viridans

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89
Q

***BOD (Biological Oxygen Demand)

A

Best test for Water Polution

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90
Q

***Catalase

A

Staph (cat+) vs Strep (cat-)

It separates Staph from Strep

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91
Q

Chick Embryo Culture

A

Virus Culture (Cannot Grow on Agar)

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92
Q

***Chocolate Agar

aka Thayer Martin Agar

aka Heated Blood Agar

A

Used for Gonorreah

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93
Q

***Coagulase

A

Staph Aureus (Coag +) vs Other Staph (Coag -)

Pathogenic vs Non-Pathogenic

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94
Q

Colliform does what for Water Purification?

A

It checks for E. coli

Determines fecal contamination in water.

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95
Q

Coombs test for what type of antigens?

A

Tests RBC antigens.

Hemolytic Anemia

Erythroblastosis Fetalis

Rh Factor

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96
Q

*Dick Test primarily used to test for____

A

Scarlet Fever

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97
Q

***Giemsa Stain used to test for _____

A

Protozoa

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98
Q

***HLA B27 (the Human Leukocyte Antegen) is testing for____

*Hint= Think PEAR

A

Seronegative Arthritides

Psoriatic arthritis

Enteropathic arthropathy (AS with ulcerative colitis or Crohns)

AS

Reiter’s

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99
Q

HLA DR5/CD4 is used for testing for____

A

AIDS

Elisa usually tests for DNA

Western Blot checks for Protein

If 2 ELISA (+) then Do a Western Blot test

If Western Blot (+) then it= AIDS

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100
Q

Mannitol Salt tests for____

A

Staph

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101
Q

Nuchal Rigidity checks for____

A

Stiff Neck

Looking for Possible Meningitis

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102
Q

***Paul Bunnell Test

A

Testing Heterophile Agglutination test for Mononucleosis

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103
Q

Phosphatase used to test____

A

if Milk Pasteurization is adequate. If all phosphatase enzymes is destroyed.

Want to check to see if Milk is HOT enough to kill phosphatase.

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104
Q

MCC of Meningitis is___

A

Strep pneumoniae

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105
Q

***Sabouraud Agar is used_____

A

to Test for FUNGI*

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106
Q

Schultz-Carlton rxn is used for______

A

to check antitoxin reaction to Scarlet Fever

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107
Q

Tissue Culture used as___

A

a Virus Culture (Cannot grow on agar)

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108
Q

***Weil Felix (serology test)

A

It is positive for all Rickettsia
EXCEPT: Coxiella burnetti (Q fever)​

Antigen for this test= Proteus vulgaris

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109
Q

Widal Test tests for____

A

Typhoid Fever

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110
Q

Tzank Test looks for____

A

Altered epitheloid Herpes Zoster & Simplex

also, Varicella

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111
Q

***What are Other tests to Test for Syphilis?

A
  • Treponema Genus
  • Spirochete
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112
Q

Non-Vinerial Syphilis YAWS is caused by what?

A

Trponema Pertenu

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113
Q

***What are tests to check for TB?

A
  • Mantoux Test= Skin Prick test
  • PPD
  • Delayed Hypersensitivity
  • Ziehl Nielson Staining
  • Acid Fast (All Mycobacterium are acid Fast)

Pneumonic: My Ass is Fast (Mycobacterium Acid Fast)

-X-Ray

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114
Q

What is the BEST test for TB?

A

Active Sputum Culture

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115
Q

***Mononucleosis is tested using_____

A
  • Heterophile antibody
  • “Heterophile Agglutination” (Paul Bunnell)
  • Downey Cell= Atypical lymphocyte on Blood Smear(Pneumonic = “Don’t Let Mono get you down”)
  • Monospot
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116
Q

When we are using sterilization or Autoclaving what are we doing?

A

Steam heat under pressure, this denatures the membranes.

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117
Q

What is Sterilization and Autoclaving innefective against?

A

Prions

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118
Q

Different Types of Vaccinations include:

A
  • Inactivated (Salk, Rabies)
  • Tetanus, Botulism
  • Measles, Mumps, Rubella, Sabin
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119
Q

Manufacturing of Vaccines come from:

A
  • Chick Embryo (Measles and Mumps vaccines)
  • Human Diploid cells (rubella, rabies, Hep A)
  • Monkey Kidney Tissue (Polio)
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120
Q

What type of study is a Case Control?

A

it ID’s Risk Factors

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121
Q

What does a Double Blind Study do?

A

Eliminates the Placebo

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122
Q

A Retrospective Study ____

A

goes back in time.

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123
Q

**When Pus (Purulent) is Blue/Green it indicates____

A

Pseudomonas aeruginosa (#1 thing seen w/ Cystic Fibrosis)

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124
Q

**When Pus (Purulent) is Red, this indicated ____

A

Serratia marcenscens

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125
Q

**A White discharge could indicate

A

Candida albicans

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126
Q

**A White PURULENT Discharge indicates____

A

Chlamydia

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127
Q

**A Yellow Pus (Purulent) discharge indicates___

A

Staph Aureus

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128
Q

**A Yellow/Green Pus (Purulent) indicates____

A

Gonorrhea

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129
Q

Formaldehyde is used for____

A

to fix Gross Specimens

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130
Q

Iodine (Mordant) is used for____

A

Pre-op disinfectant

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131
Q

Penicillin (for gram+) does what?

A

inhibits cell wall synthesis (Peptidoglycan Synthesis)

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132
Q

Tetracycline (for gram- and +) inhibits what?

A

Protein Synthesis

Also Turns Teeth Gray or Yellow /Brown

_A Broad Spectrum Antibiotic_

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133
Q

Burnet/Metchinkoff did what?

A

He developed humoral “Phagocytic” theory of immune response

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134
Q

D’Herelle, Felix did what?

A

Discovered bacteriophage, altered Virus

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135
Q

Ehrlich did what?

A

Discovered Magic Bullet… First Tx for Syphilis

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136
Q

**What was Flemming Known for?

A

Discovered Penicillin

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137
Q

**Iwanowski was known for what?

A

He discovered the First Virus. Tobacco mosaic

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138
Q

***Koch Discovered what? and proved what?

A

He Proved bacteria “causes” disease

discovered the Anthrax Vaccine

Koch’s 4 Postulates

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139
Q

**Lancefield, Rebecca did what?

A

classified Streptococcus

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140
Q

Leeuwenhoek did what?

A

Developed first microscope, and first to see microorganisms

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141
Q

***Pasteur is considered_____

A

the Father of Pathology, Father of Germ Theory(most famous)

  • Came up with Rabies Vaccine
  • Pasteurization of wine, then Milk
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142
Q

Walter Reed known for____

A

Yellow Fever

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143
Q

Sabin is associated with ____

A

Live Polio vaccine, given orally

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144
Q

Mr. Salk was responsible for____

A

Dead Polio vaccine, by injection, done before Sabin

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145
Q

Semmelweiss did what?

A

Came up with washing of hands before delivering baby and significantly reduced Puerperal Fever (aka Childbed Fever).

-Contracted by women after childbirth

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146
Q

Colony Variations: When examining an agar plate, the description of the morphology is:

  • D
  • H
  • M
  • O
  • R
  • S

What do these stand for?

A

D= Dwarf

H= Spreading

M= Mucoid capsule forming: related to virulence

O= Compact (O vs H)

R= Rough

S= Smooth

R & S stands for Colony Variations

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147
Q

Acid Fast staining is used for____

A

Mycobacterium

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148
Q

What type of Hemolysis is Alpha?

A

Partial

Green Ring

E.g. Strep pneumoniae

E.g. Strep viridans= SBE

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149
Q

What type of hemolysis is Beta?

A

Complete

Clear Ring “Beta is Bad”

E.g. Strep pyogenes

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150
Q

What type of hemolysis is Gamma?

A

None

Red Ring

E.g. Strep Mutans

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151
Q

Choclate agar is used for?

aka Heated Blood agar

aka Thayer Martin Agar

A

to check for Gonorrhea

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152
Q

Giemsa used for?

A

Protozoa

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153
Q

For Gram Staining, what is the Primary Stain?

A

Crystal violet or methylene blue.

-(Gram -) stains purple/blue

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154
Q

For Gram Staining, what is the Fixer?

A

Iodine= “Mordant”

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155
Q

For Gram Staining, what is the Decolorizer?

A

Acetone or Ethyl alcohol (Alcohol wash)

It removes teh crystal violet from thin walled (Gram -) organisms

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156
Q

In Gram Staining, what is the Counterstain?

A

Saffarin (red/pink color that goes into the Gram(-) organisms

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157
Q

Mannitol Salt is used for?

A

Staphylococcus

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158
Q

***In Cell Sex Life, what is the Conjugation stage?

A

the Plasmid DNA transfers via sex pilus.

Bestows antimicrobial resistance

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159
Q

***In Cell Sex Life, what is the Transduction stage?

A

When the Bacteriophage transfers genetic material between baceria

-Bacteriophage=Altered virus

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160
Q

***In Cell Sex Life, what is the Transformation stage for?

A

for Direct uptake of Free DNA

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161
Q

What Does CDC stand for and what is it used for?

A

Center for Disease Control

  • Statistics, NOT RESEARCH
  • Compiles Morbidity & Epidemiological Statistics
  • Located in Atlanta, GA
  • CDC DOES NOT EDUCATE!
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162
Q

What does EPA stand for and what does it do?

A

Environmental Protection Agency

-Monitors Soil, Air, and Water Quality

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163
Q

**What does FDA stand for and what does it do?

A

Food & Drugs Administration

-Regulates Health Products Released to the Public

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164
Q

*What is HHS?

A

Department of Health and Human Services

-Controls FDA, CDC, USPHS (US Public Health Services)

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165
Q

*What is NIH?

A

National Institute of Health.

  • RESEARCH!
  • NOT STATISTICS
  • Located in Bethesda, Maryland
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166
Q

**What is OSHA?

A

Occupational Safety and Health Administration

  • Makes rules concerning occupational toxicity levels of hazardous materials.
  • Responsible to Health Services Administration
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167
Q

*What is USDA?

A

US Department of Agriculture.

-Responsible for milk and milk products.

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168
Q

Emerging Cases?

A

New Disease or rapid increase of a disease

-AIDS, and EBOLA in USA were examples

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169
Q

An Endemic is_____

A

Small number of cases in Specific location. Present all the time

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170
Q

An Epidemic is when ____

A

something Rapidly affects many persons in a certain area within a few days or weeks.

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171
Q

Etiology?

A

The Study of the cause of disease.

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172
Q

***An Incidence is____

A

of New cases in a given time period.

-e.g. how many new cases last year?

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173
Q

Pandemic means?

A

more then expected # of cases of a disease worldwide.

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174
Q

***Prevalence is____

A

Total # of cases at a particular point in time.

-e.g. Total cases right now?

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175
Q

Leading Causes of Death in Infants

A
  1. Congenital Malformations
  2. Prematurity
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176
Q

Leading Causes of Death in Adults in the US

A
  1. Heart Disease
  2. Cancer
  3. Stroke
  4. Respiratory Infection
  5. Accidents
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177
Q

Leading causes of Death Worldwide

A
  1. TB
  2. Malaria
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178
Q

Water Purification Process Steps

F

F

S

S

S

A

C

A

Filtration (Filter BIG stuff w/screens)

**Flocculation** (Aluminum trichloride)

Sedimentation (Precipitate Falls)

**Sludge Digestion** (Adds anaerobic bacteria)

Sand Filtration (Removes anaerobic bacteria/ Trickling Filter)

Aeration (adds O2 to Water to improve color and Taste)

Chlorination (Kills Remaining Bacteria)

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179
Q

Worm Types

Pneumonic* Try Ronney First

A

Tapeworm= Cestodes

Roundworms= Nematodes

Fluke worms= Trematodes

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180
Q

Tapeworms Description

Head

Body

A

Head= Scolex

Body= Proglottids-egg generating segment

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181
Q

Types of Tapeworms (Cestodes)

A

Type–> Organism–> Vector–> S/Sx, Notes

Dwarf–> Hymenolepis nana –>Mouth–> Diarrhea

Beef–> Taenia saginata–> Uncooked Beef–>

Pork–> Taenia solium–> Uncooked Pork–> Causes Cysticercosis

Fish–> Diphyllobothrium latum (Fresh Water Fish)–> Mouth, contaminated Sushi–> Causes Pernicious Anemia(B12 def)

Dog/Humans–> Echinococcus granulosus–> Canine Feces–> Hydatid Cysts in liver and Lung

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182
Q

Types of Roundworms (Nematodes)

A

F

H

P

R

R

T

W

A

Ascariasis–> Oral-Fecal–> Colicky pain, lives in Small intestine

Filiariasis–> Wuchereria bancrofti–>Mosquitoes

Hookworm–> Necator americanus(Bare Foot)–> Fecal Contaminated Soil–> m/c hookworm in US

Pinworm(threadworm)–> m/c helminth in US–> butt itching

River blindness–> Onchocerca volvulus–> Flies–> In Africa

River Eye worm–> Loa Loa–> Flies–. aka “African Eyeworm”

Trichinosis–> Raw Pork–> Lives in Striated Muscles, Dx on X-ray, Biopsy of muscle confirms

Whipworm–> Trichuris Trichura–> oral-fecal–> Weight Loss

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183
Q

Type of Flukes (Trematodes)

B

I

L

P

A

*Blood–> Shistosoma japonicum–> Infested water, Host Snail–> SWIMMER’s ITCH–> mcc of death by a paracytic worm helminth worlwide!!

Intestinal–> Fasciolopsis buski–> Aquatic Plants–> Contaminated snail feces in plants

Liver–> Clonorchis sinensis–> Raw Contaminated Fish

Pulmonary(Lung)–> Paragonimus westermani–> Crayfish, mouth

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184
Q

What is a Capsomere?

A

a subunit of a protein coat (“Capsid”) of a virus particle

  • Viral envelope= trilamina lipid membrane
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185
Q

What is a Viroid?

A

ssRNA (single stranded RNA). Infects plants

  • Smaller than a virus
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186
Q

Viruses are most commonly transmitted or acquired via?

A

Respiratory System

EXCEPTIONS:

  • Arboviruses/Arthropod borne viruses= Mosquitoes/Encephalitis
  • AIDS= Sexual Transmission, IV
  • POLIO= oral/fecal
  • RABIES= bite from infected animal
  • WARTS= skin contact/ casual contact
  • HEP A= Oral/Fecal, Humans not carriers
  • HEP B= sexual transmission, IV
  • HEP C= Transfusion, tattooing
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187
Q

Herpes Simplex:

2 Types

A

Type 1: Fever Blisters(Cold Sores) ABOVE BELT, can be Trigeminal/Gasserion ganglion

Type 2: Genital Herpes BELOW BELT

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188
Q

What causes shingles in Adults, doesn’t cross the midline, and hides in the DRG? This also follows the dermatome.

A

HERPES ZOSTER

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189
Q

A pink cauliflower lesion on the female genitalia

A

Molluscum contagiosum

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190
Q

What causes German measles aka “3-day measles”?

This also causes limb malformation and is most susceptible in 1st trimester.

A

Rubella

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191
Q

What is considered RED measles?

Causes Koplik spots on buccal mucosa.

“3 Cs: Cough, Coryza(runny nose), Conjunctivitis”

A

RUBEOLA

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192
Q

***What causes Cow Pox?

A

**Vaccinia

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193
Q

***What causes maculopapularvesicular rashes, red, elevated and fluid-filled skin lesions?

A

***Varicella (Chicken Pox)

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194
Q

What causes Small Pox, and are Guarneri bodies?

A

Variola

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195
Q

Hantavirus is spread by what?

A

Rodents, including chipmunks (Prairie Dogs)

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196
Q

Polio is spread by

A

Oral/Fecal contamination.

  • Affects the anterior horn (alpha motor)
  • Bulbar type produces respiatory paralysis–> MC of Death
  • Bulbar–> Brainstem
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197
Q

What virus causes conjunctivitis, pharyngitis?

a. Adenovirus
b. Influenza
c. Mumps
d. RSV

A

Adenovirus

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198
Q

What virus causes the flu? Has antigenic shift (BIG) and/or drift (small)

a. Adenovirus
b. Influenza
c. Mumps
d. RSV

A

Influenza

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199
Q

Which of the following is caused by Sidomegalic paramyxoid virus?

This also Causes parotiditis which leads to LMN disease of CN VII (Bells Palsy)

Complications include Sterility from oophritis or orchitis?

a. Adenovirus
b. Influenza
c. Mumps
d. RSV

A

MUMPS

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200
Q

Which of the following causes croup & bronchiolitis?

a. Adenovirus
b. Influenza
c. Mumps
d. RSV

A

RSV

Respiratory Syncytial Virus

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201
Q

DO YOU NEED A BREAK FROM THIS CRAP?!

I KNOW I DO!!!

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202
Q

A mannitol salt augar is used for ______________.

A

Staphylococcus

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203
Q

Deoxyribonuclease in a medium inhibits ___________.

A

Transformation

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204
Q

Which of the following are negri bodies seen in?

A

Rabies

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205
Q

Which of the following is an advantage of passive immunity?

A

Rapid availability of protection

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206
Q

Which of the following release interleukin II?

A

T-lymphocytes

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207
Q

Which of the following does a virus cause?

A

Measles

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208
Q

Which of the following describes destruction of all microorganisms?

A

Sterilization

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209
Q

Fever blisters are associated with which of the following?

A

Herpes Simplex Type I

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210
Q

Which of the following is an acid-fast bacterium?

A

Mycobacterium

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211
Q

Which of the following is coagulase positive?

A

Staph aureus

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212
Q

Which of the following has no cell wall?

A

Mycoplasma

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213
Q

Peritrichous is a pattern of ____________.

A

Flagella

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214
Q

Which of the following causes yaws?

A

Treponema pertenunez

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215
Q

A rapid loss of fluids is associated with which of the following?

A

Cholera

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216
Q

Which of the following is Reye?s Syndrome associated with?

A

Influenza

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217
Q

Which of the following is associated with mononucleosis?

A

Epstein Barr

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218
Q

Which of the following causes atypical primary pneumonia?

A

Mycoplasma pneumoniae

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219
Q

Which of the following causes Osteomyelitis?

A

Staph aureus

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220
Q

Which type of milk is the most apt to cause disease?

A

Raw

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221
Q

Which of the following organisms causes hemorrhagic jaundice?

A

Leptospira ictohemorrhagiea

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222
Q

A throat culture predominantly pinpoints beta-hemolytic colonies of gram-positive cocci in pairs and chains which are bacitracin sensitive and not bile soluble is indicative of which of the following pathogens?

A

Strep pyogenes

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223
Q

Antibodies are synthesized and released by which of the following cells?

A

Plasma Cells

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224
Q

The best medium to identify Neisseria gonorrhea is which of the following?

A

Thayer Martin Agar (chocolate agar)

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225
Q

If a urine sample contains white blood cells white blood cell casts and bacteria it would indicate which of the following?

A

Acute Pyelonephritis

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226
Q

Which of the following does the greatest damage to the ozone layer?

A

Chlorofluorocarbons (CFC)

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227
Q

Trismus is a characteristic finding in which of the following?

A

Tetanus

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228
Q

Which of the following cell types contain heparin?

A

Basophil

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229
Q

Which part of complement is the 1st to affix to the cell membrane?

A

C3B

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230
Q

Which of the following produces helper substances?

A

CD4

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231
Q

Which infection predisposes a child to Reye?s Syndrome?

A

Influenza

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232
Q

Which of the following bacteria transmit drug resistors?

A

Plasmids

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233
Q

Which of the following cause hookworm disease?

A

Necator americans

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234
Q

Which of the following cause pinworm disease?

A

Enterohius vermicularis

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235
Q

Which of the following cause round worms?

A

Ascariasis lumbricoides

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236
Q

Which of the following immunoglobulins crosses the placenta and provides passive immunity to the fetus?

A

IgG

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237
Q

Which of the following cell types work together with T-lymphocytes to recognize foreign antigens and stimulate antibody production?

A

Macrophages

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238
Q

Which of the following government agencies is not a part of the US Public Health Service?

A

Communicable disease Center

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239
Q

Which of the following diseases cause weight loss abdominal pain and mucous diarrhea and lasts for more than 3 days?

A

Giarada

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240
Q

Which of the following is responsible for lymes disease?

A

Borrelia burgdorferi

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241
Q

Which of the following etiological agents causes epidemic typhus?

A

Rickettsia prowazeki

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242
Q

Which genera are responsible for infant diarrhea in hospital nurseries?

A

Escherichia (E. coli)

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243
Q

Which of the following parasites causes blackwater fever?

A

Plasmodium falciparum

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244
Q

Which factor is responsible for making influenza pandemic?

A

Antigenic Shift

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245
Q

Which of the following routes transmits mycoplasma hormone?

A

Sexual

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246
Q

____________ causes childhood dysentery.

A

Coxsackie Virus B

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247
Q

_________ is a eukaryotic organism.

A

Protozoa

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248
Q

The DPT vaccine offers which type of immunity?

A

Artificial Active

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249
Q

Organism of which genera usually cause allergic reactions?

A

Aspergillus

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250
Q

Which of the following organisms causes whooping cough?

A

Bacterium

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251
Q

______ is the usual cause of bladder infections.

A

E. coli

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252
Q

________ is the immunoglobulin which can be detected early in an infectious process.

A

IgM

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253
Q

Motor viruses primarily affect which system?

A

Nervous

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254
Q

Which of the following most commonly causes impetigo contagious?

A

Streptococcus pyogenes

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255
Q

Blue green pus in a wound indicates the presence of which of the following organisms?

A

Pseudomonas aeriginosa

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256
Q

What is the most common organism to affect a patient with AIDS?

A

Pneumocytstic carinii

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257
Q

The helminth that causes the most deaths worldwide belongs to which genera?

A

Schistosoma (found in water)

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258
Q

________ cells process antigen.

A

Macrophages

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259
Q

_________ can penetrate unbroken skin.

A

Schistosoma mansoni

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260
Q

Which of the following does a vector not transmit?

A

Fever

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261
Q

Which of the following is a result of the reaction between soluble antigen and a specific antibody?

A

Precipitation

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262
Q

Vitamin B12 deficiency often results from which worm infestation?

A

Diphyllobothrium latum

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263
Q

Organisms from which genera are used as antigen in the diagnosis of Rickettsia disease?

A

Proteus

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264
Q

Destroying the larva of parasites from the genera Ascariasis Schistosoma and Trichinella is a distinctive function of ___________.

A

Eosinophils

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265
Q

Which of the following organisms is coagulase positive?

A

Staph aureus

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266
Q

Which parasite is most apt to infect the person who has been walking barefoot in a pile of feces?

A

Necatur americans

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267
Q

Which of the exhibits a gray pseudomembrane?

A

Diphtheria

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268
Q

Pasteurization is complete when the ___________ organism has been killed.

A

Brucellosis

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269
Q

What is the purpose of pasteurization?

A

To stop the growth of Bacteria

270
Q

Which of the following is characteristic of a pyogenic organism?

A

Pus Formation

271
Q

Which of the following is a pathogen found in contaminated water?

A

Leptospira interrogans

272
Q

Which of the following causes Legionnaire?s Disease?

A

Bacteria

273
Q

Which of the following sexually transmitted organisms causes Pelvic Inflammatory Disease and infertility?

A

Chlamydia trachomatis

274
Q

Which of the following causes Bacillary Dysentery?

A

Shigella

275
Q

What is a common characteristic of diphtheria?

A

Pharyngeal Pseudomembrane

276
Q

Which of the following increases when a parasitic infection is present?

A

Eosinophils

277
Q

Which of the following is the primary pathological consequence of Malarial infection?

A

Erythrocyte Destruction

278
Q

Which of the following diseases is a result of phage induction in Staphylococci?

A

Osteomyelitis

279
Q

Bacterial capsules are generally composed of a high molecular weight. Which of the following is one?

A

Polysaccharides

280
Q

Respiratory syncytial virus is the major cause of Bronchiolitis and Pneumonia in which of the following?

A

Infants

281
Q

Which of the following conditions is associated with Koplik spots?

A

Rubella

282
Q

Bacteria which grows @ 55øc or higher are known as __________.

A

Thermophile

283
Q

Which of the following organisms cause hard black subcutaneous nodules around the scalp?

A

Piedri hortae

284
Q

Which of the following is primarily found in hard water?

A

Calcium Magnesium and Salts

285
Q

Which of the following conditions is caused by Clostridium perfungies?

A

Gas Gangrene

286
Q

Which of the following immunoglobulins mediates type I hypersensitivity reaction?

A

IgE

287
Q

Which of the following has been implicated in river blindness?

A

Onchocerca

288
Q

The Bacillus calmette gueron vaccine provided immunity against which of the following?

A

Tuberculosis

289
Q

What is the virus that causes Gengivostomatitis?

A

Herpes Simplex I

290
Q

Which of the following is related to the transmission of Measles?

A

Respiratory Inhalation

291
Q

Which of the following causes purulent vaginal discharge and burning?

A

Neisseria gonorrhea

292
Q

Influenza pandemic occurs because of which of the following?

A

Antigenic shift

293
Q

Which of the following parasites causes Cysticercosis?

A

Taenia solium

294
Q

Which of the following increases the immunogenic sympathetic soluble thymogen?

A

Immunoglobulins

295
Q

Which of the following is associated with an encapsulated Diplococcus?

A

Neisseria

296
Q

Chlorinated hydrocarbons that are stored in the bone can be most destructive to which of the following?

A

CNS

297
Q

Which of the following organisms is most responsible for fecal contamination of water?

A

E. coli

298
Q

Which of the following sources of water contain the most sulfur?

A

Rain Water

299
Q

Which of the following is the step before flocculation in water treatment?

A

Filtration

300
Q

Which of the following elements is prevalent in significant amounts in ground water?

A

Radon

301
Q

Which of the following cells in the plasma contain interleukin II?

A

T-lymphocytes

302
Q

Which of the following is involved in the transmission of Hepatitis A?

A

Ingestion

303
Q

The causative agent of ringworm is a ______________.

A

Fungus

304
Q

Which of the following organisms cause thrush?

A

Candida albicans

305
Q

Coccidioidomycosis is a fungus that affects which of the following?

A

Lungs

306
Q

Which of the following can aggravate C-3?

A

Plasmin

307
Q

Which of the following is found in the infectious stage of Necator americanus?

A

Trophozoite

308
Q

Which of the following cells produce interleukin I?

A

Mononuclear Phagocytes

309
Q

Which of the following cells produce Histamine?

A

Mast Cells

310
Q

Scolex on a tapeworm is for which of the following?

A

Attachment to Intestinal Mucosa

311
Q

Transmission of Herpes II from mother to newborn is _____________.

A

Perinatal

312
Q

Secondary amoebic infection will spread to which organ?

A

Liver

313
Q

What causes Otitis media?

A

Hemophiles influenza

314
Q

Conjugation involves which of the following structures?

A

Pilus

315
Q

What is the cause of a heroin addict who has fever tremors muscles spasms and red streaks over the injection site?

A

Strep pyogenes

316
Q

Which of the following causes stomach ulcers?

A

Helicobacter pylori

317
Q

Which of the following is the vector of St. Louis encephalitis?

A

Mosquito

318
Q

Which of the following is found in farmers who breathe in hay or grain dust?

A

Farmers Lung

319
Q

Ringworm is diagnosed using which of the following?

A

Ultra Violet (woods lamp)

320
Q

In what phase do bacteria divide @ a constant rate?

A

Log

321
Q

Which of the following is the Vector for Rocky Mountain Spotted Fever?

A

Tick

322
Q

What has been responsible for the greatest increase in life expectancy?

A

Control of Infectious Disease

323
Q

Which of the following is most apt to be found in a muscle biopsy?

A

Trichimonis

324
Q

Which of the following is not a water borne disease?

A

Shigella (contaminated soil)

325
Q

Zehl Nelson stain is used to detect which of the following?

A

Acid Fast Bacilli

326
Q

Which of the following diseases is spread via the fecal/oral route?

A

Polio

327
Q

Which of the following strains of E. coli cause travelers diarrhea?

A

Entertoxogenic

328
Q

Schistosoma affects what part of the body?

A

Blood

329
Q

Which of the following causes fungal infection of the lung?

A

Histoplasmosia and Coccidiomycosis

330
Q

Which of the following causes acute Osteomyelitis?

A

Staph aureus

331
Q

Clostridium ___________ causes gas gangrene and myconecrosis.

A

Perfringens

332
Q

Which of the following is a process by which colloidal particles settle out from solution?

A

Flocculation

333
Q

Penicillin acts by preventing formation of _______ in bacteria.

A

Peptioglycans

334
Q

Which of the following pathogens causes Colitis secondary to antibiotic treatment?

A

Clostridium difficile

335
Q

Which of the following is in saliva and tears?

A

IgA

336
Q

Which of the following U.S. Government Agency compiles data on outbreaks of disease?

A

CDC (center for disease control)

337
Q

Which of the following is a cause of subacute bacterial endocarditis?

A

Strep viridians

338
Q

Epidemic parotitis is associated with ___________.

A

Mumps

339
Q

What organism causes diphtheria?

A

Bacterium

340
Q

What cells produce antibodies in response to an antigen?

A

Plasma Cells

341
Q

What is the most common hookworm in the U.S.?

A

Necator americanus

342
Q

Tetanus toxoid neutralizes _________________.

A

Circulating Toxins

343
Q

Active digestion of organic material occurs @ which stage of sewage treatment?

A

Trickling

344
Q

Which of the following organisms lacks a cell wall?

A

Mycoplasma

345
Q

Which of the following federal agencies is responsible for lab experiment standards?

A

NIH (nation institute of health)

346
Q

Which of the following is responsible for atypical primary pneumonia?

A

Mycoplasma pneumonia

347
Q

Erythromatous ring seen in scarlet fever comes from which of the following?

A

Strep

348
Q

Which organism is responsible for common form food poisoning?

A

Staph aureus

349
Q

Trypansoma gambiense primarily affects what?

A

Brain

350
Q

Which of the following cells produces Interleukin II?

A

T-Helper Cells

351
Q

Which of the following immunoglobulins is most predominant in the neonate?

A

IgG

352
Q

Which scientist is credited with bacterial transformation?

A

Griffith

353
Q

Recent outbreaks from E. coli are due to which of the following?

A

Enteropathogenic

354
Q

The incidence of disease is best defined as the total number of ____________.

A

New Cases Appearing In A Given Time

355
Q

What type of food poisoning is obtained from improperly canned foods?

A

Botulism

356
Q

Which of the following is toxic does not have DNA but still has protein?

A

Prion

357
Q

Which of the following organisms causes Rheumatic Fever?

A

Group A Lancefield

358
Q

Hepatic Whitlow occurs in which of the following?

A

Fingers

359
Q

Which of the following agencies writes and publishes literature?

A

WHO

360
Q

Salk vaccine is considered to be ______________.

A

Inactive Polio

361
Q

How does UV radiation destroy organisms?

A

Destroys The DNA

362
Q

Which of the following causes Scalded Skin Syndrome?

A

Staph aureus

363
Q

When there is an epidemic spread of a disease which of the following is most important?

A

The Vector

364
Q

Which of the following transmits Hepatitis A?

A

Fecal/Oral

365
Q

Which of the following causes rice water stools?

A

Cholera

366
Q

Which of the following antibiotics is used to treat resistant strains of Staph aureus?

A

Vancomycin

367
Q

Iodine used in gram staining is considered a __________.

A

Modant

368
Q

Which of the following causes symptoms similar to Mono?

A

Cytomegalovirus

369
Q

Which of the following produces a toxin that does not allow Ach to be released @ the myoneural junction?

A

Clostridium tetani

370
Q

Which of the following is catalase and coagulase negative?

A

Staph aureus

371
Q

Which of the following parasites is found around the anus and is detected by the scotch tape test?

A

Enterobius vermicu

372
Q

Which of the following is the most common PID?

A

Neisseria gonorrhea

373
Q

Exposure to chickenpox and measles will impart which of the following immunities?

A

Natural Active

374
Q

Which of the following is the organism most responsible for urinary tract infection?

A

E. coli

375
Q

Trypanosonia cruzi is the organism that causes ______________.

A

Chagas Disease

376
Q

The etiological agent of Lymes Disease is _______________.

A

Borrelia Burgdorferi

377
Q

Which of the following is involved in immediate hypersensitivity reactions?

A

IgE

378
Q

Salmonella poisoning is most commonly due to ingestion of ______ and ________.

A

Eggs and Poultry

379
Q

Which process has contributed to the decline in the incidence of food poisoning?

A

Proper Cooking

380
Q

Which organism most commonly affects AIDS patients?

A

Fungus

381
Q

Lymphocytes release _________ in response to a viral infection.

A

Interferon

382
Q

Which of the following is a causative agent in smallpox?

A

Variola

383
Q

Candylomata lata are found in what stage of Syphilis?

A

Secondary

384
Q

Which of the following is used to measure sewage contamination?

A

Coliforms

385
Q

Which of the following Rickettsia diseases is found in contaminated milk?

A

Q Fever

386
Q

Which of the following cells is present in an antibody to antigen reaction?

A

B-Lymphocytes

387
Q

What is the most common way to be infected by Toxoplasmosis?

A

Feline Feces

388
Q

The presence of a red streak that appears along the course of a blood vessel would indicate development of ____________.

A

Bacteremia

389
Q

Which of the following is the Federal Agency that sets lab standards?

A

NIH

390
Q

The ELISA Test is for ________.

A

AIDS

391
Q

Which of the following Federal Agencies sets the standards for the work place?

A

OSHA

392
Q

Which of the following has pear shaped double nuclei and 4 pair of flagella?

A

Giardia lamblia

393
Q

Which of the following Federal Agencies funds research?

A

NIH

394
Q

Which of the following is a characteristic of Staph aureus?

A

Active and Invasive Opportunist

395
Q

What zoonosis disease do spores spread?

A

Anthrax

396
Q

What is the mode of transmission for German Measles?

A

Respiratory Droplets

397
Q

Which scientist is responsible for the prevention of food borne disease?

A

Pasteur

398
Q

Which of the following Government Agencies focuses on biomedical research?

A

NIH

399
Q

A 10 year old with a stiff neck severe headache nausea vomiting 104ø temperature tachycardia and meningitis without a rash has what?

A

Equine encephalitis

400
Q

Which of the following results in passive naturally acquired immunity?

A

Breast Feeding

401
Q

What is the 1st line of human cellular defense against viral infection?

A

Humoral Response

402
Q

Which bacteria are primarily responsible for spontaneous abortion in cattle?

A

Brucclia

403
Q

What is the primary site of campylobacteriasis?

A

Intestine

404
Q

Which of the following consumes inorganic material?

A

Autotroph

405
Q

The brain and the peripheral nervous system produce which of the following immunoregulatory chemicals?

A

Interleukin I (macrophage) Gamma Globulins (B-cells)

406
Q

Which of the following does Herpes Simplex Type II cause?

A

Genital Herpes

407
Q

The rash caused by Rocky Mountain Spotted Fever originates in which of the following areas of the body?

A

Ankles and Wrist

408
Q

Which of the following conditions are caused by Staph aureus?

A

Carbuncles Emphentygo Osteomyelitis Scalded Skin Syndrome Toxic Shock

409
Q

A mature adult parasite makes its permanent home in the ______________.

A

Definitive Host

410
Q

The common cold is spread via _________.

A

Air

411
Q

AIDS virus attacks which of the following?

A

CD4 and Cytotoxic T-Cells

412
Q

What is the most common fungal condition in the Ohio Valley and Mississippi Valley areas?

A

Histoplasmosis

413
Q

Protozoa are found in water in which of the following forms?

A

Cyst Form

414
Q

What is the function of a bacterial capsule?

A

Prevents Bacterial Phagocytosis

415
Q

Delayed hypersensitivity is _______________.

A

Cell Mediated

416
Q

Which of the following fluoresces under light?

A

Pseudomonas aeriginosa

417
Q

Which of the following is associated with childhood dysentery?

A

Coxsackie Virus

418
Q

What is the most likely outcome of a Hepatitis A Virus infection?

A

Full Recovery

419
Q

What is the most likely cause if a patient presents with blurred vision 103ø temperature fever diarrhea and headache?

A

Clostridium botulinum

420
Q

What is the mode of transmission for Wool Sorters Disease?

A

Inhalation of Bacillus anthrax spores

421
Q

Trismus (lock jaw) is caused by which of the following?

A

Clostridium Tetani

422
Q

Extrinsic asthma is characterized by increased _____________.

A

Serum IgE Levels

423
Q

What is the most common cause of lead poisoning in the U.S.?

A

Industrial Waste

424
Q

Parasitic infections will increase which of the following?

A

Eosinophils

425
Q

What type of immunity is imparted to a person who has taken DPT vaccine?

A

Artificial Active

426
Q

Ingestion and digestion of solid foods by cells of the body is ____________.

A

Phagocytosis

427
Q

Which of the following causes Baciliary dysentery?

A

Shigella

428
Q

Iodine functions as a ______________ in gram staining procedure.

A

Mordant

429
Q

Which of the following causes Thrush?

A

Candida albicans

430
Q

Which of the following is Acid Fast?

A

Mycobacterium

431
Q

Which of the following causes blue-green pus?

A

Pseudomonas aeriginosa

432
Q

Which of the following is the most appropriate test to determine acid-fast bacilli?

A

Ziehl Nielson

433
Q

What is the function of a bacterial capsid?

A

Protects Nuclear material

434
Q

What is the probable cause of a 4 year old that presents with upper respiratory infection pharyngitis laryngitis a red pharynx and a 102ø fever?

A

Hemophilus influenza

435
Q

What is the most common cause of childhood diarrhea?

A

Reovirus

436
Q

Antibodies which provide immunity against Streptococcus pneumoniae react with the __________________.

A

Capsular Polysaccharide

437
Q

What is the best way to test for Typhus?

A

Blood

438
Q

What is the vector for Leishmaniasis?

A

Sandfly

439
Q

Negri bodies are found in ____________.

A

Rabies

440
Q

Which of the following does not produce an exotoxin?

A

Baciliary dysentery

441
Q

Which of the following produce exotoxin?

A

Clostridium tetani Staph aureus Strep pyogenes

442
Q

Water borne infections are derived mostly from _______________.

A

Giardia lamblia

443
Q

Mannitol salt agar is used to detect which of the following?

A

Pathogenic Staph

444
Q

How is Hepatitis Virus vaccine produced?

A

Synthetically Manufactured

445
Q

A patient with koplik spots probably is infected with what?

A

Rubella

446
Q

A Darkfield microscope is used to identify which of the following?

A

Treponema pallidum (syphilis)

447
Q

Coliform count is used to detect which of the following?

A

Inadequate Sewage Disposal

448
Q

Microorganisms that live @ 20-45ø C are classified as which of the following?

A

Mesophiles

449
Q

BCG vaccine is used to prevent which of the following?

A

TB

450
Q

Who is the scientist responsible for categorizing Streptococci?

A

Lancefield

451
Q

Which of the following produces hard red non-painful lesions on the penis?

A

Syphilis

452
Q

Which of the following is responsible for San Joaquin Valley Fever?

A

Coccidiodes immitis

453
Q

Which portion of the body is most affected by the Herpes Virus?

A

Nervous System

454
Q

What is the most common method of transmission for hookworm infection?

A

Through the Skin

455
Q

Precipitation from solution in the form of fleecy masses is the definition for which of the following?

A

Flocculation

456
Q

Which of the following carries Equine encephalitis?

A

Mosquito

457
Q

What is the worst form of malaria?

A

Plasmodium falciparum

458
Q

Plasmodium fits into which of the following categories?

A

Protozoa

459
Q

A severe lack of both B and T lymphocytes is associated with which of the following?

A

Leukemia

460
Q

Retrovirus is typically ____ to ______.

A

RNA DNA

461
Q

Which of the following is the reason that the FDA requires pasteurization of eggs across state lines?

A

To Prevent Salmonella

462
Q

The Fluke known as Paragonia westermani is found in the _______.

A

Lung

463
Q

A rash on the hands and feet is characteristic of which of the following?

A

Rocky Mountain Spotted Fever

464
Q

Which of the following does not display immunoglobulin?

A

Type IV

465
Q

Ascariasis lumbricoides is transmitted via which of the following?

A

Fecal/Oral

466
Q

Mast cells are most closely correlated with which of the following?

A

Basophiles

467
Q

Which of the following is not fully funded by the Federal Government?

A

CDC

468
Q

Genital Herpes is associated with which of the following?

A

Type II Herpes

469
Q

Herpes Simplex I is associated with which of the following?

A

Sores

470
Q

Which of the following fungi cause jock itch?

A

Tinea cruris

471
Q

The largest portion of air pollution in the U.S. comes from _______________.

A

Carbon Monoxide

472
Q

Which of the following organisms is associated with Lymes disease?

A

Borrelia burgdorferi

473
Q

Which of the following have flagella @ both ends?

A

Peritrichous

474
Q

Vibrio cholera will produce which of the following?

A

Water and Mucous in the Stool

475
Q

Which of the following is associated with inflammation of the nerves in the face and brain?

A

Herpes

476
Q

What is the secondary step in sewage treatment?

A

Use of Microorganisms to Digest Materials

477
Q

Which of the following cause Rocky Mountain Spotted Fever?

A

Rickettsia rickettsia

478
Q

Chloride plus water results in which of the following?

A

Hydrochloric Acid

479
Q

Putting in ____________ cleans a septic tank.

A

Microorganisms

480
Q

Which of the following is an immune complex performed by the body?

A

C1-C4-C3-C5

481
Q

Delayed hypersensitivity is associated with which of the following?

A

Type IV Cell Mediated Response

482
Q

What is the diagnosis for a 30-year-old male who presents with a fever and skin lesions that appear as eccentric rings on the trunk?

A

Lymes Disease

483
Q

Which of the following is associated with Gas Gangrene?

A

Clostridium perfringens

484
Q

Which of the following does a vector not transmit?

A

Q Fever

485
Q

Which of the following is associated with the common cold?

A

Rhinovirus

486
Q

Hemophilus influenza is most dangerous for ____________.

A

Newborns

487
Q

Shigella causes which of the following?

A

Bacillary dysentery

488
Q

Rose-colored spots on the abdomen are associated with which of the following?

A

Salmonella Typhosa

489
Q

T-helper cells activate which of the following?

A

B-lymphocytes

490
Q

Which of the following immunological reactions does not display immunoglobulin response?

A

Type IV

491
Q

What is the fungus that affects the body?

A

Tinea corporis

492
Q

Which of the following can spread the common cold?

A

Air and Fomites

493
Q

A foul smelling fishy discharge is associated with which of the following?

A

Gardenella Vaginalis

494
Q

What are plantar warts caused by?

A

Virus

495
Q

Which of the following is the diagnostic test for Tb?

A

Mantoux

496
Q

Which of the following spreads epidemic typhus?

A

Body Lice

497
Q

What is the etiological agent that causes epidemic typhus?

A

Rickettsia prowazeki

498
Q

What are the genera responsible for infant diarrhea in hospital nurseries?

A

E. coli

499
Q

Which of the following cause Black Water Fever?

A

Plasmodium falciforum

500
Q

How is Mycoplasma homonis transmitted?

A

Sexually

501
Q

Which of the following is a Eukaryotic organism?

A

Protozoa

502
Q

Which genera cause allergic reactions?

A

Aspergillus

503
Q

Which of the following causes whooping cough?

A

Bacterium

504
Q

Which of the following is detected earliest in the infection process?

A

IgM

505
Q

Motor viruses primarily affect which of the following?

A

Nervous System

506
Q

Impetigo contagiosa is most commonly caused by ____________.

A

Strep pyogenes

507
Q

What is the most common organism to affect a person with AIDS?

A

Pneumolcystis carinii

508
Q

Which of the following is the Helminth that causes the most deaths worldwide?

A

Schistosoma

509
Q

Which of the following cells process antigen?

A

Macrophages

510
Q

Which of the following can penetrate unbroken skin?

A

Schistosoma mansoni

511
Q

Which of the following results in a reaction between a soluble antigen and a specific antibody?

A

Precipitation

512
Q

Which of the following causes a B12 deficiency?

A

Diphyllobothrium latum (fishworm)

513
Q

A throat culture that produces pinpoint beta-hemolytic colonies of gram-positive cocci in pairs and in chains which are bacitracin sensitive and not bile soluble would indicate which of the following?

A

Strep pyogenes

514
Q

Antibodies are synthesized and released by which of the following?

A

Plasma Cells

515
Q

What is the best medium to identify Neisseria gonorrhea?

A

Chocolate Agar

516
Q

If a urine sample has WBC?s WBC casts RBC?s and Bacteria in it you should investigate for which of the following?

A

Acute Pyelonephritis

517
Q

Which of the following contain heparin?

A

Basophiles and Mast Cells

518
Q

Which is the 1st part of the complement to affix to the cell membrane?

A

C3B

519
Q

Which of the following produces helper substances?

A

CD4

520
Q

Which of the following infections predisposes a child to Reye?s Syndrome?

A

Influenza

521
Q

Which of the following transmits drug resistors?

A

Plasmids

522
Q

Which of the following cause hookworm disease?

A

Necator americanus

523
Q

Which of the following crosses the placenta and provides passive immunity to the fetus?

A

IgG

524
Q

Which of the following work with T-Cells to recognize foreign antigens and stimulate antibody production?

A

Macrophages

525
Q

Which of the following is not part of the U.S. Public Health Services?

A

CDC

526
Q

Which of the following causes weight loss abdominal pain mucous diarrhea and lasts for more than 3 days?

A

Giardia lamblia

527
Q

Which of the following is TB in the spine?

A

Pott?s

528
Q

What is the envelope around the capsid derived from?

A

Host Cell Membrane

529
Q

What is the primary site of campylobacteriasis?

A

Intestine

530
Q

Which of the following causes a fungus ball in the lung?

A

Aspergillus

531
Q

Where does the highest number of anaerobic bacterial growth occur in sewage treatment?

A

Sludge

532
Q

Which of the following is associated with the causative agent of mononucleosis?

A

Epstein Barr

533
Q

Which of the following causes hemorrhagic jaundice?

A

Leptospira ictohemorrhagea

534
Q

Which of the following is associated with encapsulated diplococcus?

A

Neisseria

535
Q

Chlorinated hydrocarbons that enter the body through the bone can be most destructive to the ___________.

A

CNS

536
Q

Which of the following water sources contain the most sulfur?

A

Rain Water

537
Q

What is the step subsequent to (after) flocculation in water treatment?

A

Sedimentation

538
Q

What are the steps of water treatment in order?

A

Flocculation Sedimentation Filtration Aeration

539
Q

At what stage is backwashing used in drinking water treatment?

A

Filtration

540
Q

Which of the following is present in significant amounts in ground water sources?

A

Radon

541
Q

Which cells in plasma contain interleukin II?

A

T- lymphocytes

542
Q

Where do malarial parasites reproduce?

A

Inside RBC?s

543
Q

Which of the following can activate C3?

A

Plasmin

544
Q

Which of the following is found in the infective stage of Necator americanus?

A

Trophozoite

545
Q

Which of the following is a result of phage induction in Staphylococcus?

A

Osteomyelitis

546
Q

Respiratory syncytial virus is a major cause of bronchiolitis and pneumonia in which of the following?

A

Infants

547
Q

What is the etiological agent of mononucleosis?

A

Epstein Barr

548
Q

A patient from South America presents with coffee ground vomiting and severe nosebleeds. He relates a history of severe headaches for the past 4 days jaundice body aches insomnia and nausea. The most likely diagnosis is which of the following?

A

Yellow Fever

549
Q

Bacteria which grow @ 55øC or higher are _____________.

A

Thermophiles

550
Q

Which of the following cause black subcutaneous nodules around the scalp?

A

Piedri hortae

551
Q

What are the properties of Streptococcus as a result of lysogenic conversion?

A

Erythrogenic Toxin

552
Q

Which Federal Agency regulates the management of hazardous waste?

A

EPA

553
Q

Which of the following mediate Type I hypersensitivity reactions?

A

IgE

554
Q

Bacillus calmette gueron vaccine (BCG) provides immunity against which of the following?

A

TB

555
Q

Which virus causes gengivostomatitis?

A

Herpes Simplex I

556
Q

Which of the following is related to the transmission of Measles?

A

Inhalation

557
Q

Which of the following causes purulent vaginal discharge and burning?

A

Neisseria gonorrhea

558
Q

Which of the following causes cysticercosis?

A

Taenia solium

559
Q

What is the most common cause of death in the U.S.?

A

Heart Disease

560
Q

What would be the diagnosis for a child who presents with a rash around the buttocks due to a parasitic condition?

A

Enterobius vermicularis

561
Q

What is the most common symptom of Cholera?

A

Rice Water Stools

562
Q

Which of the following is the vector for Western Equine Encephalitis?

A

Mosquito

563
Q

A gray pseudomembrane in the back of the throat is associated with which of the following?

A

Diphtheria

564
Q

Which of the following is characteristic of a pyogenic organism?

A

Pus Formation

565
Q

Which of the following is a pathogen found in contaminated water?

A

Leptospira interrogans

566
Q

Fungi imperfecti are so named because of what reason?

A

No Sexual Spores

567
Q

Which of the following is a common characteristic of diphtheria?

A

Pharyngeal Pseudomembrane

568
Q

What is the primary pathological consequence of malaria?

A

Erythrocyte Destruction

569
Q

What is the primary allergen to which a child reacts in barley rye and wheat?

A

Gluten

570
Q

The toxoid for tetanus produces which of the following forms of immunity?

A

Artificial Active

571
Q

The TB skin test represents which of the following responses?

A

Type IV Delayed

572
Q

Which of the following kills all microbes?

A

Autoclaving

573
Q

Which of the following do mites transmit?

A

Scabies

574
Q

What substance found in milk determines if pasteurization has been properly accomplished?

A

Phosphatase

575
Q

Where does a mature tapeworm live?

A

Small Intestine

576
Q

What is the diagnosis for a person who has just moved to Arizona and develops a dry cough associated with climatic conditions?

A

Coccidiomycosis

577
Q

Which of the following passes through the placenta?

A

IgG

578
Q

Which of the following is most prevalent?

A

IgG

579
Q

Which of the following best describes the TB test?

A

Delayed Hypersensitivity

580
Q

Which of the following supplies money to local doctors for research?

A

NIH

581
Q

What is the stage of water purification that removes most of the bacteria?

A

Sedimentation

582
Q

Which type of sterilization is most suited for instruments used in surgery?

A

Moist Heat

583
Q

What does an excessive amount of fluoride in drinking water cause?

A

Mottled Teeth

584
Q

Which of the following is a fungus of the scalp?

A

Tinea Capitis

585
Q

Which of the following is most dangerous to newborns?

A

Staph aureus

586
Q

What is the most common way that Legionnaire?s disease is spread?

A

Respiratory Droplets

587
Q

Which of the following causes Chaga?s disease?

A

Trypanosoma cruzi

588
Q

A patient presents with normal body temperature widespread muscle spasm and muscle guarding in the abdominal area. What do these symptoms suggest?

A

Botulism

589
Q

Type IV delayed immunological reaction will affect which of the following?

A

Lymphocytes

590
Q

What do T-helper cells activate?

A

B-lymphocytes

591
Q

What is the best test to perform to determine the pollution of water?

A

Biological Oxygen Demand (BOD)

592
Q

Which of the following is an example of a Type I reaction?

A

Bronchial Asthma

593
Q

Which of the following is an immunoglobulin associated with Type I?

A

IgE

594
Q

Which immunoglobulin is found in Gastric Mucosa?

A

IgA

595
Q

Methyl gas causes cancer of the __________.

A

Kidney

596
Q

There is no vaccine for which of the following?

A

Rhinovirus

597
Q

Cook pork to avoid which of the following?

A

Trichinella spiralis

598
Q

Antibodies respond to antigens via _____________.

A

B-lymphocytes

599
Q

Which immunoglobulin crosses the placenta?

A

IgG

600
Q

Which immunoglobulin is involved in Type II hypersensitivity?

A

IgG and IgM

601
Q

Which of the following has both endotoxin and exotoxin?

A

Shigella dysentery

602
Q

Pink Eye is associated with which of the following?

A

Haeomphilus aegypticus

603
Q

Which of the following is an air-borne carcinogen?

A

Benzopyrene

604
Q

Which of the following is associated with infant botulism?

A

Raw Honey

605
Q

Which of the following has been eliminated from society?

A

Variolla

606
Q

Which of the following secrete histamine?

A

Basophiles

607
Q

What is the result of warm moist heat on cell membranes?

A

Protein Denaturization

608
Q

Which types of Hepatitis can you get from a blood transfusion?

A

Hepatitis B and C

609
Q

Soap added to a sterilizing agent will do which of the following?

A

Increase The Bacteriocidal Potential

610
Q

Who is considered to be the father of immunology?

A

Pasteur

611
Q

Which of the following is associated with muscle spasms and calcification of skeletal muscle?

A

Trichimonis spiralis

612
Q

Which of the following produce the most circulating antibodies?

A

Plasma Cells

613
Q

Infant methemoglobinemia is due to which of the following?

A

Nitrate

614
Q

Which of the following is a lung disease due to iron dust inhalation?

A

Siderosis

615
Q

The most effective sterilization technique in a lab is ___________.

A

Autoclaving

616
Q

Which of the following is an air pollutant that causes headaches and dizziness?

A

Carbon Monoxide

617
Q

Contaminated milk transmits which of the following?

A

Q Fever

618
Q

Herpes Simplex does not create which of the following?

A

Lifetime Immunity

619
Q

Flocculation is involved in which of the following?

A

Colloid Aggregation During Sewage Treatment

620
Q

Bladder infections are most commonly due to which of the following?

A

E. coli

621
Q

Opsonins agglutinins lysins and precipitins are which of the following?

A

Antibodies

622
Q

Which of the following diminishes riboflavin?

A

Milk Left Standing in Light

623
Q

Black death is due to which of the following?

A

Yersenia pestis

624
Q

Which of the following can be found in unpasteurized milk?

A

Brucella abortis

625
Q

Why are flu vaccines sometimes not effective?

A

Different Strains

626
Q

Why is a vaccine for the common cold not feasible?

A

The multiplicity of it

627
Q

What type of organism uses molecular O2 as the final electron acceptor?

A

Obligate Aerobe

628
Q

An autotroph consumes which of the following?

A

Inorganic Materials

629
Q

Neisseria gonorrhea can be best identified in which of the following?

A

Thayer Martin Agar (chocolate agar)

630
Q

Childhood dysentery is due to which of the following?

A

Coxsackie Virus

631
Q

Safarin is used in which staining technique?

A

Gram Stain

632
Q

Herpes Simplex produces a latent infection where?

A

Nervous System

633
Q

What is the purpose of iodine use in gram staining?

A

Fixer (mordant)

634
Q

A virus capsid is made up of which of the following?

A

Protein

635
Q

Which of the following are classified by their method of locomotion?

A

Protozoa

636
Q

What is the test to determine whether or not complete pasteurization has been achieved?

A

Phosphatase Test

637
Q

Q Fever is due to which of the following?

A

Coxiella burnetti

638
Q

What is the name of the serology test for Rickettsia?

A

Weil felix

639
Q

Histoplasma is a fungal infection that mimics which of the following?

A

TB

640
Q

Bacterial cell walls are made up of __________________.

A

Peptidoglycans

641
Q

What is iodine used for in pre-op?

A

Disinfectant

642
Q

Lymph node enlargement is not associated with ________.

A

Cholera

643
Q

The heaviest and largest immunoglobulin is ____.

A

IgM

644
Q

Microbial pollution is eliminated via which of the following?

A

Sand Filtration

645
Q

Who discovered yellow fever?

A

Reed

646
Q

Chymosis (bruising) is seen with which of the following?

A

Scurvy

647
Q

Which of the following increases immunogenic sympathetic soluble thymogen?

A

Immunoglobulins

648
Q

Which of the following can cross the placenta and affect the fetus?

A

Rubella

649
Q

Exotoxins can act upon ____________ cell walls.

A

Phospholipid

650
Q

Which of the following contributes to environmental problems?

A

Automobiles

651
Q

Which of the following is an arbovirus?

A

Western Equine Encephalitis

652
Q

Penicillin affects bacteria by interfering with synthesis of ______________.

A

Peptidoglycans

653
Q

The kissing bug causes which of the following?

A

Chaga?s Disease

654
Q

The State Health Department is responsible for maintaining which of the following?

A

Mortality Rates

655
Q

Where are nosocomial infections acquired?

A

Hospitals

656
Q

Why is chlorine added to treated sewage?

A

To Destroy Residual Microbes

657
Q

Red spots on the face are associated with which of the following?

A

Cutaneous Anthrax Infection

658
Q

Streptobacillus is the agent of which of the following?

A

Rat Bite Fever

659
Q

The sedimentation stage of water purification removes most of the _________.

A

Bacteria

660
Q

Anaphylaxis is associated with which of the following?

A

Type I Hypersensitivity

661
Q

Which of the following organisms oxidize inorganic matter for energy?

A

Autotrophs

662
Q

Which of the following organisms require organic matter for energy?

A

Heterotrophs

663
Q

Which of the following use dead decaying matter for energy?

A

Saprophytes

664
Q

Which of the following feed on living matter for energy?

A

Parasites

665
Q

Which of the following describes 2 populations living together in which 1 or both benefit?

A

Symbiosis

666
Q

Which of the following describes 2 populations living together in which both benefit?

A

Mutualism

667
Q

Which of the following describes 2 populations living together in which both benefit and both accomplish what neither can do alone?

A

Synergism

668
Q

Which of the following describes 2 populations living together in which one benefits and the other is unaffected?

A

Commensalism

669
Q

Which of the following are tests for syphilis?

A

Darkfield Kahn Kline TPI VDRL Wasserman

670
Q

Which of the following are tests for tuberculosis?

A

Acid Fast = Ziehl Nielson Stain BCG = TB vaccine Mantoux Test Tine Test

671
Q

Which of the following are pasteurization methods?

A

Flash Holding Method Ultrahigh Method