Microbiology of Periodontal Diseases Flashcards
______ periodontitis is a slowly progressing, sporadic, unpredictable form of the disease; whereas, __________ periodontitis is a site-specific, destructive, rapidly progressing form of the disease.
Chronic
Aggressive
Periodontitis results from a defect in which cell type?
Neutrophil
**primary defense against sulcular bacteria*
Bacteria interact with host _____ and ____ .
tissue
innate immune system
How does the host inflammatory response influence progression disease?
the host inflammatory response attempts to keep microbes under control, BUT inflammation provides nutrients to the bacteria and causes collateral tissue damage.
If tissue damage does not include bone, the issue is reversible and is called _______. If it includes bone, it is not reversible and is called ______.
gingivitis
periodontitis
Where does the constant supply of nutrients come from?
sulcular fluid flow
Why is the tooth structure considered unique?
hard tissue that is NON-shedding
What are the three zones of subgingival plaque biofilm?
Unattached Plaque
Epithelium Attached Plaque
Tooth Attached Plaque
______ bacteria or ________ released from the biofilm will invade connective tissue will possibly invade epithelial cells.
Planktonic
microcolonies
Which type of bacteria will promote inflammation?
tissue-invasive
If bacterial tissue invasion is deep (close to bone), why does this lead to bone loss?
Osteoclast activity is prolonged
Osteoblast activity is blocked
Bacteria can invade host cells and obtain nutrient by stimulation of _______.
autophagy (protein breakdown)
Pathogenic species of bacteria can subvert host innate immune response pathways and enable _______ to overgrow or invade.
commensals
What kind of bacterial species exist in the periodontal pocket?
mix of 700 possible species
gram NEG and gram POS both exist
anaerobic
proteolytic
Proteolytic bacteria are to periodontal pockets; as ______ bacteria are to supragingival plaque.
saccharolytic
