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Year 5 - Pathology > Microbiology > Flashcards

Microbiology Flashcards

1
Q

How does chronic meningitis present, and what are the likely causative pathogens?

A

Headaches for months

TB or Cryptococcus neoformans

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2
Q

What are the common causative bacteria in meningitis, and how would you differentiate them on a Gram stain?

A

Neisseria meningitides - pink/red = Gram -ve

Streptococcus pneumoniae - violet = Gram +ve

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3
Q

What are the most likely causative bacteria of meningitis in the elderly?

A

GBS
Listeria monocytogenes
Mycobacterium tuberculosis (subacute)

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4
Q

What are the risk factors for meningitis caused by N. meningitides?

A

Complement deficiency
Hyposplenism
Hypogammaglobulinaemia

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5
Q

What are the risk factors for meningitis caused by S. pneumoniae?

A 
Complement deficiency
Hyposplenism
Immune defect (alcoholic)
Infection (pneumonia)
Entry fracture
Previous head trauma with CSF leak
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6
Q

What antibiotic covers Listeria in meningitis management?

A

Ampicillin

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7
Q

What investigations should be done for suspected meningitis?

A 
Blood cultures
Serum-Ag
EDTA-PCR
Throat swab
LP
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Year 5 - Pathology (5 decks)

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