Microbiology

Question 1

Multiples of tb seen at the pleural surface

Answer 1

Ghon focus

Question 2

Upper lobes showing caseating granuloma with fibrosis and calcification

Answer 2

Post primary tuberculosis

Question 3

Fastest test for tb

Answer 3

ZN/Auramine staining of the sputum

Question 4

Mainstay of treatment for tb

Answer 4

Rifampicin
Isoniazid
Pyrazinamide
Ethambutol

Question 5

Which tb medication makes you orange and is hepatotoxic

Answer 5

Rifampicin

Question 6

Which tb medication causes peripheral neuropathy

Answer 6

Isoniazid

Question 7

Which tb medication causes hyperuracaemia and hepatotoxicity

Answer 7

Pyrazinamide

Question 8

Which tb medication causes optic neuritis and visual disturbances

Answer 8

Ethambutol

Question 9

Incubation time for mycobacterium leprae

Answer 9

2-10 years

Question 10

M. Marinum is seen in who?

Answer 10

Swimming pool/aquarium owners

“Fish tank granuloma”

Question 11

Patient with a painless nodule which then progresses to an ulcer, scar and contractures. Becomes incredibly deforming

Answer 11

Mycobacterium ulcerans

Question 12

Bronchitis

Answer 12

Inflammation of the medium sized airways
Cough and sputum for three months for two years.
Normal c-X-ray

Question 13

Rusty sputum and a lobar pneumonia shown on the X-ray

Answer 13

S. pneumonia

Question 14

Smoker with pneumonia. Grows gram negative coco-bacilli

Answer 14

H. Influenza

Question 15

Recent viral infection and now a pneumonia with cavitation on chest X-ray.

Answer 15

S. aureus

Question 16

Alcoholic with haemophysis and pneumonia. Gram negative rods are grown

Answer 16

Klebsiella pneumonia

Question 17

Four classical causes of pneumonia

Answer 17

S. pneumonia
H. Influenza
S. aureus
K. Pneumonia

Question 18

Three atypical causes of pneumonia

Answer 18

Legionella pneumophilia
Mycoplasma pneumonia
Chlamydia psittaci

Question 19

Patient who fits air conditioning for a job presents with pneumonia, low sodium.
What investigation would you do to confirm the causative agent?

Answer 19

Legionella Pneumophilia

Urine antigen test

Question 20

Pneumonia which is cold agglutinin test positive and causes erythema multiforme

Answer 20

Mycoplasma pneumonia

Question 21

Three encapsulated organisms

Answer 21

H influenza
S pneumonia
N meningitidis

Question 22

Pneumonia in patient with cystic fibrosis and the recommended treatment

Answer 22

Pseudomonas aeriginosa

Give tazocin

Question 23

Antibiotic for MRSA

Answer 23

Vancomycin

Question 24

Three C’s predisposing one to C. Difficile infection

Answer 24

Clindamycin
Cephalosporins
Ciprofloxacin

Question 25

Treatment for c difficile

Answer 25

Metronidazole

Question 26

Obligate intracellular gram negative bacteria

Mucopurulent cervicitis/urethral discharge

Answer 26

Gonorrhoea

Question 27

Treatment for gonorrhoea

Answer 27

Im ceftriaxone 250 mg

Question 28

Gold standard test for gonorrhoea

Answer 28

Urethral smear culture

Question 29

Complications of gonorrhoea in men and women

Answer 29

PID/prostatitis

Question 30

Obligate intracellular pathogen with elementary bodies and reticulate particles

Answer 30

Chlamydia

Question 31

Diagnostic gold standard for chlamydia

Answer 31

Nucleic acid amplification test

Question 32

Treatment for chlamydia

Answer 32

Azithromycin Ig stat and 7 days doxycycline