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MRCOG Part 1 > Microbiology > Flashcards

Microbiology Flashcards

1
Q

Toxoplasmosis - cause?

A

T. Gondii

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2
Q

Toxoplasma gondii - what type of pathogen?

A

Intracellular protozoan parasite

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3
Q

Consequences of infection with toxoplasmosis in pregnancy?

A

Miscarriage
Fetal abnormalities (increased risk if infection <10/40):
Microcephaly
Hydrocephalus
Cerebal calcifications
Cerebral palsy
Epilepsy
Choroidoretinitis
Thrombocytopenia

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4
Q

How to diagnose toxoplasmosis?

A

PCR or Immunoglobulins (IgM, IgG and IgA).
MRI/CT: ring enhancing lesions

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5
Q

Treatment of toxoplasmosis?

A

Recommended in pregnancy if recent infection
ie. Spiromycin + Pyimethamine, sulfazadine, folinic acid

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MRCOG Part 1 (7 decks)

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