microbiology Flashcards

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1
Q

what type of bacteria has a more complex cell wall

A

gram negative

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2
Q

does a gram positive cell have an outer lipopolysaccharide wall layer

A

no

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3
Q

does a gram negative have an outer lipopolysaccharide wall layer

A

yes

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4
Q

what does gram positive retain in stain

A

retain crystal violet/iodine

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5
Q

what does gram negative retain in stain

A

retain salfranin

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6
Q

heamolysis test is for

A

streptococcus

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7
Q

coagulase test is for

A

staphylococcus

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8
Q

alpha heamolytic

A

partial heamolysis on blood agar - green

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9
Q

what are strep viridans and strep pneumoniae

A

alpha haemolytic

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10
Q

beta haemolytic

A

complete haemolysis

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11
Q

what is strep pyogenes

A

beta heamolytis

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12
Q

gamma haemolytic

A

no reaction

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13
Q

what is enterobcoccus

A

gamma haemolytic

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14
Q

what does hemolysis test

A

the bacterias ability to lyse red blood cells

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15
Q

coagulase of staph aureus

A

positive

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16
Q

transformation gene transfer

A

DNA from dead bacteria taken up by living bacteria through which plasmid DNA can be transferred

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17
Q

conjugation gene transfer

A

sex pilus (fimbrae) produced by one bacteria through which plasmid DNA can be transferred

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18
Q

Transduction gene transfer

A

viruses infecting bacteria can transfer bits of DNA from one bacterium to another

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19
Q

staphylococcus, streptococcus, enterococcus

A

gram positive cocci

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20
Q

what is clostridium

A

gram positive rod

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21
Q

what is listeria

A

gram positive rod

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22
Q

what is bacillus

A

gram positive rod

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23
Q

what is neiserria

A

gram negative cocci

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24
Q

what is pseudunomas

A

gram negative rod

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25
Q

what is salmonella

A

gram negative rod

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26
Q

what is shigella

A

gram negative rod

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27
Q

what is klebsiella

A

gram negative rod

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28
Q

what is bacteroids

A

gram negative rod

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29
Q

what is escherichia

A

gram negative rod

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30
Q

what is hemophilus

A

gram negative rod

31
Q

what is campylobacter

A

gram negative rod

32
Q

what is helicobacter

A

gram negative rod

33
Q

what is legionella

A

gram negative rod

34
Q

what is a spirochete

A

long helically coiled cells

35
Q

examples of spirochetes

A

lyme disease, syphilis, treponema, leptospira

36
Q

pathogen

A

harmful organism

37
Q

commensal

A

organism that is part of normal flora

38
Q

what is opportunistic pathogen

A

probably only cause infection in immunocompromised individuals

39
Q

what is a contaminant

A

an organism that has got into culture by accident

40
Q

what is pathogenicity

A

the ability of a microorganism to produce disease

41
Q

what is virulence

A

degree of pathogenecity of an organism

42
Q

what are good antibiotics

A

selectively toxic

43
Q

what do antibiotics effect

A

all parts of the body including the normal bacteria flora

44
Q

bactericidal

A

kill bacteria

45
Q

bacteristatic

A

inhibit bacterial growth

46
Q

when given orally how long does it take for antibiotics to reach peak serum levels

A

1 hour

47
Q

when given IV how long does it take for antibiotics to reach peak serum levels

A

15 minutes

48
Q

what antibiotics attack protein synthesis

A

tetracyclines, aminoglycosides, lincosamides, macrolides

49
Q

what are doxycylcine and tetracyline

A

tetracylines

50
Q

what do tetracyclines target

A

gram + /-

51
Q

what is steptomicin and gentamicin

A

amino glycosides

52
Q

what do aminoglycosides target

A

gram -

53
Q

what are clindamycin and lincomycin

A

lincosamides

54
Q

what do lindosamides target

A

gram +

55
Q

what is erythromycin and azithromycin

A

macrolides

56
Q

what do macrolides target

A

gram -

57
Q

what antibiotics target cell wall

A

cephalosporins, penicillin, carbapenems, glycopeptides

58
Q

what are ceftriaxone and cefepime

A

cephalosporins

59
Q

what do cephalosporins target

A

gram +/-

60
Q

what are ampicillin, amoxicillin, coamoxiclav, flucloxacillin, penicillin

A

penicillins

61
Q

what do penicillins target

A

+/-

62
Q

what are meropenm and ertampenem

A

carbenems

63
Q

what are teicoplanin and vacomycin

A

glycopeptides

64
Q

what do glycopeptides target

A

gram +

65
Q

what do carbapenems target

A

-/+

66
Q

what do fluoroquinolones target

A

DNA

67
Q

what are ciprofloxacin and levofloxacin

A

flouroquinolones

68
Q

what do fluoroquinolines target

A

+/-

69
Q

4 C antibiotics

A

cephalosporins, co amoxiclav, clindamycin, ciproflocaxin

70
Q

what to avoid in pregnancy

A

metronidazole, chlorampehenicol, aminoglycosides, tetracylcines

71
Q

what enzymes destroy antibiotics

A

betalactamase, extended spectrum lactamase, carbapenase

72
Q

what do beta lactamase have

A

resistance to early penicillins

73
Q

what do extended spectrum beta lactamase have

A

resistance to all penicillins and cephalosporins

74
Q

what does carbenamse have

A

resistance to all penicillins, cephalosporins and carbapenems