Microbio Pathogens

Question 1

Causes of Hepatitis A-E?

Answer 1

Hep A = Picornavirus  (ssRNA, naked)
Hep B = Hepadnavirus  (dsDNA, enveloped)
Hep C = Flavivirus  (ssRNA, enveloped)
Hep D = Deltavirus (ssRNA, enveloped)
Hep E = HepEvirus  (ssRNA, naked)

Question 2

3 main viral causes of Bronchitis/Bronchiolitis?

Answer 2

RSV (paramyxovirus), Influenza A (orthomyxovirus), & Coronavirus

(all enveloped RNA viruses)

Question 3

Viral cause of Rubella (German measles)?

Answer 3

Togavirus (enveloped RNA)

Question 4

Viral cause of Mumps?

Answer 4

Paramyxovirus (enveloped RNA)

Question 5

Viral cause of Erythema Infectiosum?

Answer 5

Parvovirus (naked ssDNA)

Question 6

What 3 pathologies are caused by Parvovirus B19?

Answer 6

1. Erythema Infectiosum (fifth disease)
2. Aplastic crises in Sickle Cell Anemia
3. Hydrops Fetalis

Question 7

Bacteria that form a clear area of hemolysis on blood agar?

Answer 7

Staph aureus (catalase & coagulase positive)

Strep pyogenes - group A strep (catalase negative & bacitracin sensitive)

Strep agalactiae - group B strep (catalase negative & bacitracin resistant)

Listeria monocytogenes (tumbling motility, meningitis in newborns, unpasteurized milk)

Question 8

Toxic Shock Syndrome (TSST) - Presentation & Cause?

Answer 8

P: Fever, vomiting, rash, desquamation, shock, end-organ failure

C: S. aureus food poisoning due to ingestion of preformed toxin

Question 9

Which staph organism can form a clot around itself leading to abscess & what is the clot made of?

Answer 9

Staph aureus can form a fibrin clot around itself, leading to abscess

Question 10

Strep pneumonia is the leading cause of what diseases?

Answer 10

Meningitis, Otitis media (in children), Pneumonia, Sinusitis

“MOPS”
“Strep pneumonia MOPS are Most OPtochin Sensitive”

Question 11

What is ass’d w/ “rusty” sputum, sepsis in sickle cell anemia, & splenectomy?

Answer 11

Streptococcus pneumoniae

Question 12

Name the Viridans group Streptococci:

a) Normal flora of the oropharynx & cause dental carries
b) Subacute bacterial endocarditis @ damaged valves

Answer 12

a) Strep mutans
b) Strep sanguis

Viridans group strep live in the mouth b/c they are not afraid “of the chin” (Optochin resistant)