MicroB Flashcards
Which of the following is most suitable for prophylaxis against P. Vivax
a) Mefloquine
b) Quinine
c) Primaquine
d) Atovaquone
e) Doxycycline
C. P. vivax (& P. ovale) produce a latent stage (hypnozoites – 1 to 2 week incubation) that resides in the liver; Requries Primaquine to eradicate them. Artemisinin combination therapy often used for parasites/malaria. (Artemisinin is Nobel prize winning drug)
Which of the following statements about Hepatitis B vaccine is incorrect?
A. It can be administered intramuscularly
B. It is effective in preventing Hepatitis B
C. It can prevent Hepatits D
D. It is effective in curing carriers
E. It should be given to patients with chronic Hepatitis C
D
What is one of the presentations for HSV2?
meningoencephalitis
genital sores
recurrent oral sores
keratitis
pharyngitis
B
Serology test for dengue specific for IgM
a. usually appear within 7 days from infection
b.no false positive results
c.appears 1 week after primary infection
d. shows that the patient is immune
e.always better than antigen testing
C
TRUE regarding toxoplasmosis
a.severity decreases with gestational period
b. transmission decrease with gestational period
c. triad of symptoms seen in mother
d.common cause of hydrocephalus
A
A man with HIV has purple lesions on his arm which are diagnosed as Kaposi’s Sarcoma. Which of the following is not true:
A) it is a cancer of the keratinocyte stem cells of the skin.
B) It is uncommon except in HIV.
C) It is caused by Kaposi’s Sarcoma associated Herpes Virus
D) it carries oncogenes that produce VEGF
E) There is autocrine signaling to cause endothelial cell proliferation
A
Describe the Acinetobacter species
Which statement regarding hepatitis viruses is FALSE:
a) Fulminant hepatitis may occur in some patients with Hepatitis A virus infection
b) The chances of an adult becoming a chronic carrier are higher following an infection with Hepatitis B virus than with Hepatitis C virus.
c) There is a higher probability that vertical transmission of Hepatitis B virus occurs than Hepatitis C virus.
d) Hepatitis D virus can only replicate in cells already infected with Hepatitis B virus
e) There is a higher mortality associated with acute Hepatitis E virus infection than with acute Hepatitis A virus infection.
b
How is Hep B vaccine derived
Vaccine is dervied from mammalian cell-based chinese hamster ovary cell; human plasma is the 1st gen one
Which is an effect of aminoglycosides?
A) Binds to 30S subunit of bacterial ribosome
B) Causes misreading of RNA code
C) Inhibits Peptidyl Transferase
D) Stabilises polysomes
E) Is bacteriostatic
A
Zidovudine:
A) effectively prevents mother to child transmission of AIDS
B) is usually given as a single treatment
C) is a cytosine analogue
D) penetrate blood brain barrier
E) is non-toxic to bone marrow
A
What is associated with eosinophilia?
a) Bacillus in gram negative stain
b) Mammilated eggs in stools
c) Owl’s eye inclusions
d) Lewy bodies in CSF
B
Vaccine for splenectomised individuals?
A) HAV
B) HBV
C) DPT
D) Pneumococcal
E) BCG
D
Risk factors for S. pneumoniae
How do we detect immunity to mycobacterium tuberculosis?
A) Mantoux test
B) skin prick test
C) red cell agglutination test
D) allergen specific IgG
E) T cell proliferation assay
A
