Microalbumin Testing Flashcards

1
Q

What is the principle behind the Microalbumin testing using the Micral-Test?

A) Polymerase chain reaction (PCR)
B) Chromatography
C) Radioimmunoassay
D) Enzyme immunoassay

A

D) Enzyme immunoassay

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2
Q

What is the sensitivity range of Micral-Test in microalbumin testing using immunologic tests?

A) 10 to 20 mg/dL
B) 5 to 15 mg/dL
C) 0 to 10 mg/dL
D) 15 to 25 mg/dL

A

C) 0 to 10 mg/dL

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3
Q

Which components are utilized in the Micral-Test for microalbumin testing?

A) Platinum-labeled antibody, B-galactosidase, Phenolphthalein
B) Gold-labeled antibody, B-galactosidase, Chlorophenol red galactoside
C) Silver-labeled antibody, Alkaline phosphatase, Bromothymol blue
D) Titanium-labeled antibody, Lysozyme, Methyl orange

A

B) Gold-labeled antibody, B-galactosidase, Chlorophenol red galactoside

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4
Q

Which factor can lead to a false-negative result in Microalbumin testing using the Micral-Test?

A) Elevated albumin levels
B) Acidic urine
C) Dilute urine
D) Presence of glucose

A

C) Dilute urine

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5
Q

What is the principle behind the Immunologic test called ImmunoDip for Microalbumin Testing?

A) Enzymatic Assay
B) Nephelometry
C) Immunochromographics
D) Fluorescence Polarization

A

C) Immunochromographics

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6
Q

What is the sensitivity range of the ImmunoDip for microalbumin testing?

A) 0.5 to 2.0 mg/dL
B) 1.2 to 8.0 mg/dL
C) 5.0 to 10.0 mg/dL
D) 10.0 to 15.0 mg/dL

A

B) 1.2 to 8.0 mg/dL

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7
Q

What is the main component of the reagents used in ImmunoDip for Microalbumin Testing?

A) Red blood cells
B) Antibody-coated blue latex particles
C) Enzyme-linked antibodies
D) Fluorescent molecules

A

B) Antibody-coated blue latex particles

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8
Q

What is a potential factor leading to a false-negative result in Microalbumin testing using ImmunoDip?

A) Increased urine concentration
B) Presence of contaminants in the urine
C) High ambient temperature during testing
D) Dilute urine

A

D) Dilute urine

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9
Q

What is the principle behind the Albumin: Creatinine Ratio in microalbumin testing?

A) Measures the absolute concentration of albumin in urine
B) Evaluates the total protein-to-creatinine ratio in urine
C) Utilizes sensitive albumin tests related to creatinine concentration
D) Quantifies the creatinine concentration to correct for albumin levels

A

C) Utilizes sensitive albumin tests related to creatinine concentration

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10
Q

What reagent is used in Microalbumin testing for the Albumin: Creatinine Ratio in Immunologic Tests?

A) Albumin dye bis (3’,3” - diiodo- 4’, 4” - dihydroxy- 5’,5” -dinitrophenyl)- 3,4,5,6- tetrabromo sulphonphtalein Green to aqua blue

B) Creatinine dye bis (3’,3” - diiodo- 4’, 4” - dihydroxy- 5’,5” -dinitrophenyl)- 3,4,5,6- tetrabromo sulphonphtalein Green to aqua blue

C) Immunoglobulin dye bis (3’,3” - diiodo- 4’, 4” - dihydroxy- 5’,5” -dinitrophenyl)- 3,4,5,6- tetrabromo sulphonphtalein Green to aqua blue

D) Hemoglobin dye bis (3’,3” - diiodo- 4’, 4” - dihydroxy- 5’,5” -dinitrophenyl)- 3,4,5,6- tetrabromo sulphonphtalein Green to aqua blue

A

A) Albumin dye bis (3’,3” - diiodo- 4’, 4” - dihydroxy- 5’,5” -dinitrophenyl)- 3,4,5,6- tetrabromo sulphonphtalein Green to aqua blue

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11
Q

Which substances are involved in the color change reaction during Microalbumin testing using the Albumin: Creatinine Ratio method?

A) Copper sulfate (CuSO4)
B) 3,3’,5,5 - tetramethylbenzidine
C) Diisopropyl benzene dihydroperoxide
D) All of the above

A

D) All of the above

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12
Q

What is the basis of sensitivity in the immunologic test called Albumin: Creatinine Ratio for microalbumin testing?

A) Enzymatic activity of copper-creatinine complexes
B) Pseudo peroxidase activity of copper-creatinine complexes
C) Fluorescence emission of albumin-creatinine complexes
D) Ion exchange capacity of copper-creatinine complexes

A

B) Pseudo peroxidase activity of copper-creatinine complexes

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13
Q

What is the normal range for the Albumin: Creatinine Ratio in microalbumin testing?

A) 1 to 5 mg/L
B) 50 to 100 mg/L
C) 10 to 150 mg/L
D) 200 to 300 mg/L

A

C) 10 to 150 mg/L

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14
Q

What is the normal range for the Albumin: Creatinine Ratio in microalbumin testing?

A) 0.1 to 5 mg/dL, 0.01 to 0.5 mmol/L
B) 10 to 300 mg/dL, 0.9 to 26.5 mmol/L
C) 50 to 150 mg/dL, 4.5 to 13.4 mmol/L
D) 2 to 20 mg/dL, 0.18 to 1.8 mmol/L

A

B) 10 to 300 mg/dL, 0.9 to 26.5 mmol/L

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15
Q

Which factor may interfere with the accuracy of Microalbumin testing using the Albumin: Creatinine Ratio in immunologic tests?

A) High protein intake
B) Dehydration
C) Visibly bloody or abnormally colored urine
D) Recent exercise

A

C) Visibly bloody or abnormally colored urine

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16
Q

Which of the following statements regarding microalbumin testing and immunologic tests is accurate?

A) Microalbumin testing is primarily based on creatinine measurements.
B) The Albumin: Creatinine Ratio is not affected by any medications.
C) Creatinine may lead to false positives in microalbumin testing when taking Tagamet.
D) Immunologic tests for albumin are not influenced by medication interactions.

A

C) Creatinine may lead to false positives in microalbumin testing when taking Tagamet.