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Micro Uw2 Flashcards

1
Q

HPV 6 and 11

A

Anogenital warts/ condylomata acuminata

Pink/skin color papules

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2
Q

P falciparum Mc

A

Multiple small rings on giemsa stain
Trophozoites
Artemisinin, atovaquone-proguanil

Sub Saharan Africa
New Guinea
D republic
Haiti

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3
Q

P vivax and ovale

A

Dormant forms: hypnozoites
Primaquine

Central and South America
Western pacific region

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4
Q

Leishmaniasis

A

Parasitic
Sandflies
Giemsa stain: Amastigotes (spherical/ovoid bodies)
Ampho B

Africa, Southeast Asia, the Americas

Subacute fever, malaise, abdo pain, splenomegaly.

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5
Q

Filariasis

A

Mosquito
Diethylcarbamazine
Nematode

Lymphatic and subcutaneous tissue
Giemsa: micro filaria

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6
Q

Trypanosomiasis

A

Protozoal
Sleeping sickness
CNS: meningoencephalitis
Giemsa: trypanosomes
Nifurtimox

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7
Q

Pyrimethamine

A

Treat: Toxoplasmosis
Encephalitis in AIDS

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8
Q

Arbo viruses RNA
Summer months

A

West Nile: acute asymmetric flaccid paralysis
St. Louis encephalitis
La crosse
Eastern n western equine encephalitis

Arthropod: Mosquito, tick.
Host: birds n small mammals.

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9
Q

Histoplasmosis

A

Ohio n Mississippi River valleys

Bird/bat droppings

CNS: focal brain lesions (rare)

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10
Q

Enteroviruses

A

Coxsackie
Echo

Fecal-oral

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11
Q

N gonorrhoea n chlamydia

A

Ceftriaxone n doxycycline

C: no peptidoglycan cell wall

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12
Q

N. Go

A

Antigenic variation in surface molecules
Porins, opa proteins, lipooligosaccharide

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13
Q

C. Septicum

A

Spore
Exotoxin
Gram positive
Colon cancer
Hematogenous spread
No trauma
Hemorrhagic Bullae

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14
Q

C perfringens

A

Trauma

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15
Q

Vibrio vulnificus

A

In hemochromatosis
Needs iron to grow

Gram n

Shellfish
Wound in seawater

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16
Q

Multiple myeloma

A

❌Lymphocyte function
⬇️plasma cells
S pneumonia
H influenza
E. coli, uti

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17
Q

Rota virus

A

Children
Nonbloody diarrhea
Intussusception

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18
Q

Shiga toxin E. coli
Shigella

A

Bloody diarrhea
HUS

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19
Q

GBS causing virus

A

C jejuni
Zika
Epstein Barr
Cyto
HIV

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20
Q

C parvum

A

Protozoan
Acid fast stain in stool
PCR
Immuno assay

Sporozoits mature to meronts and reinvade host (auto infection)

21
Q

Thayer Martin agar

A

Neisseria organisms

Chocolate sheep blood agar
Vancomycin
Colistin
Nystatin
Trimethoprim

22
Q

Protease inhibitors

A

❌HIV protease from cleaving gag-pol proteins

Immature non infectious virions due to
❌production of functional viral proteins

23
Q

GP120 n 41

A

HIV envelope proteins

Viral attachment and fusion with host cell membrane

From GP160 (env gene)

24
Q

CCR5 inhibitors

25
Fusion inhibitors
Enfuvirtide
26
Protease inhibitors
Saquinavir Ritonavir Indinavir
27
RTI
Efavirenze Tenofovir Lamivudine
28
Integrase inhibitors
Raltegravir
29
M pneumonia
I antigen Cold agglutinin
30
Lipooligosaccharide
Endotoxin ⬆️severity of necrosis in N meningitidis
31
Polysaccharide capsule
N. Meningitidis Resist phagocytosis and complement activation
32
IgA protease
N meningitidis Nasopharyngeal epithelial colonization
33
Lipoteicholic acid
In cell wall of gram positive bacteria
34
TSS
S aureus super antigen exotoxins
35
C. Botulinum
Symmetric descending weakness
36
Zika virus
SS RNA flavivirus Aedes mosquito Newborn: subcortical calcification, microcephaly, loss of brain mass
37
CMV
Hearing loss Chorioretinitis Jaundice Periventricular calcification
38
Parvovirus B19
SS DNA virus ❌erythroid progenitor cells Fetal hydrops in pregnancy
39
Rubella
SS RNA Cardiac defects Hearing loss Cataracts
40
Conjugation
Resistance for shigella antibiotics Direct contact between bacteria cells Pillus
41
Transduction
Introducing foreign DNA in bacteria cell by a virus or viral vector
42
Transformation
Uptake of free DNA from the environment via cell membrane.
43
Transposition
Movement of DNA sequence from one location to another in the genome.
44
HPV
Nonenvelop Double stranded DNA virus
45
HPV 16 and 18
Oropharyngeal carcinoma (tonsil, base of tongue) Cervix, vulva, anus, penis E6 and E7 proteins ❌ apoptosis
46
HPV 1 and 2
Skin warts
47
HPV 6 and 11
Anogenital (upper respiratory tract)
48
HSV
Latent in sensory nerves
49
HAV
RNA picornavirus Fecal oral

Micro (6 decks)

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