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Micro > Micro Uw2 > Flashcards

Micro Uw2 Flashcards

1
Q

HPV 6 and 11

A

Anogenital warts/ condylomata acuminata

Pink/skin color papules

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2
Q

P falciparum Mc

A

Multiple small rings on giemsa stain
Trophozoites
Artemisinin, atovaquone-proguanil

Sub Saharan Africa
New Guinea
D republic
Haiti

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3
Q

P vivax and ovale

A

Dormant forms: hypnozoites
Primaquine

Central and South America
Western pacific region

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4
Q

Leishmaniasis

A

Parasitic
Sandflies
Giemsa stain: Amastigotes (spherical/ovoid bodies)
Ampho B

Africa, Southeast Asia, the Americas

Subacute fever, malaise, abdo pain, splenomegaly.

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5
Q

Filariasis

A

Mosquito
Diethylcarbamazine
Nematode

Lymphatic and subcutaneous tissue
Giemsa: micro filaria

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6
Q

Trypanosomiasis

A

Protozoal
Sleeping sickness
CNS: meningoencephalitis
Giemsa: trypanosomes
Nifurtimox

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7
Q

Pyrimethamine

A

Treat: Toxoplasmosis
Encephalitis in AIDS

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8
Q

Arbo viruses RNA
Summer months

A

West Nile: acute asymmetric flaccid paralysis
St. Louis encephalitis
La crosse
Eastern n western equine encephalitis

Arthropod: Mosquito, tick.
Host: birds n small mammals.

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9
Q

Histoplasmosis

A

Ohio n Mississippi River valleys

Bird/bat droppings

CNS: focal brain lesions (rare)

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10
Q

Enteroviruses

A

Coxsackie
Echo

Fecal-oral

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11
Q

N gonorrhoea n chlamydia

A

Ceftriaxone n doxycycline

C: no peptidoglycan cell wall

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12
Q

N. Go

A

Antigenic variation in surface molecules
Porins, opa proteins, lipooligosaccharide

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13
Q

C. Septicum

A

Spore
Exotoxin
Gram positive
Colon cancer
Hematogenous spread
No trauma
Hemorrhagic Bullae

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14
Q

C perfringens

A

Trauma

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15
Q

Vibrio vulnificus

A

In hemochromatosis
Needs iron to grow

Gram n

Shellfish
Wound in seawater

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16
Q

Multiple myeloma

A

❌Lymphocyte function
⬇️plasma cells
S pneumonia
H influenza
E. coli, uti

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17
Q

Rota virus

A

Children
Nonbloody diarrhea
Intussusception

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18
Q

Shiga toxin E. coli
Shigella

A

Bloody diarrhea
HUS

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19
Q

GBS causing virus

A

C jejuni
Zika
Epstein Barr
Cyto
HIV

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20
Q

C parvum

A

Protozoan
Acid fast stain in stool
PCR
Immuno assay

Sporozoits mature to meronts and reinvade host (auto infection)

21
Q

Thayer Martin agar

A

Neisseria organisms

Chocolate sheep blood agar
Vancomycin
Colistin
Nystatin
Trimethoprim

22
Q

Protease inhibitors

A

❌HIV protease from cleaving gag-pol proteins

Immature non infectious virions due to
❌production of functional viral proteins

23
Q

GP120 n 41

A

HIV envelope proteins

Viral attachment and fusion with host cell membrane

From GP160 (env gene)

24
Q

CCR5 inhibitors

A

Maraviroc

25
Q

Fusion inhibitors

A

Enfuvirtide

26
Q

Protease inhibitors

A

Saquinavir
Ritonavir
Indinavir

27
Q

RTI

A

Efavirenze
Tenofovir
Lamivudine

28
Q

Integrase inhibitors

A

Raltegravir

29
Q

M pneumonia

A

I antigen

Cold agglutinin

30
Q

Lipooligosaccharide

A

Endotoxin
⬆️severity of necrosis in N meningitidis

31
Q

Polysaccharide capsule

A

N. Meningitidis

Resist phagocytosis and complement activation

32
Q

IgA protease

A

N meningitidis

Nasopharyngeal epithelial colonization

33
Q

Lipoteicholic acid

A

In cell wall of gram positive bacteria

34
Q

TSS

A

S aureus super antigen exotoxins

35
Q

C. Botulinum

A

Symmetric descending weakness

36
Q

Zika virus

A

SS RNA flavivirus
Aedes mosquito

Newborn: subcortical calcification, microcephaly, loss of brain mass

37
Q

CMV

A

Hearing loss
Chorioretinitis
Jaundice
Periventricular calcification

38
Q

Parvovirus B19

A

SS DNA virus

❌erythroid progenitor cells

Fetal hydrops in pregnancy

39
Q

Rubella

A

SS RNA

Cardiac defects
Hearing loss
Cataracts

40
Q

Conjugation

A

Resistance for shigella antibiotics

Direct contact between bacteria cells

Pillus

41
Q

Transduction

A

Introducing foreign DNA in bacteria cell by a virus or viral vector

42
Q

Transformation

A

Uptake of free DNA from the environment via cell membrane.

43
Q

Transposition

A

Movement of DNA sequence from one location to another in the genome.

44
Q

HPV

A

Nonenvelop
Double stranded DNA virus

45
Q

HPV 16 and 18

A

Oropharyngeal carcinoma (tonsil, base of tongue)

Cervix, vulva, anus, penis

E6 and E7 proteins ❌ apoptosis

46
Q

HPV 1 and 2

A

Skin warts

47
Q

HPV 6 and 11

A

Anogenital (upper respiratory tract)

48
Q

HSV

A

Latent in sensory nerves

49
Q

HAV

A

RNA picornavirus
Fecal oral

Micro (6 decks)

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