Micro management Flashcards
Brucellosis
Doxycycline and Streptomycin
Meningitis Empirical more than 50 years
IV Cefotaxime + Amoxicillin
Q Fever
Doxycycline
Meningococcal Meningitis
IV Benzylpenicillin or Cefotaxime
Strongyloides Stercoralis
Thiabendazole, Albendazole, Ivermectin
Gonorrhoea
Single dose IM Ceftriaxone 1g
if sensitive to Ciprofloxacin –> single dose oral ciprofloxacin 500mg
If Ceftriaxone is refused –> oral cefixime 400mg + oral azithromycin 2g single dose only
Cholera
Oral rehydration therapy
Role fo doxycycline or ciprofloxacin
Legionella
Erythromycin or Clarithromycin
Rabies
If Immunised –> give 2 further doses
If nont immunised –> Human rabies immunoglobulin with full course of vaccine
Cellulitis
Flucloxacillin(clarithromycin or clindomycin if penicillin-allergic)
Toxoplasmosis
Pyrimethamine + Sulphadiazine for 6 weeks
Trypansomiasis African
Early: IV Pentamidine or Suramin
Late: IV Melarosoprol
Impetigo
Topical fusidic acid, oral flucloxacillin or erythromycin if widespread
Amoebiasis
Metronidazole (trophozoite stage) Diloxanide Furoate (dormant cystic stage)
Meningitis Pre-Hospital
IM Benzylpenicillin
Leprosy
Rifampicin, Dapsone and Clofazimine
Uncomplicated community-acquired pneumonia
Amoxicillin, (Doxycycline or clarithromycin in penicillin allergic, add flucloxacillin if staphylococci suspected e.g. In influenza)
Meningitis by Haemophilus Influenzae
IV Cefotaxime
Leptospirosis
Benzylpenicillin or Doxyycline
Hepatitis A Post Exposure Prohpylaxis
Hepatitis A Vaccine and Human Normal IgG
Lyme Disease
Doxycycline or Amoxicillin if early disease
Ceftriaxone if disseminated
Pubic Lice
Deconatminate clothes and bedding
Permethrin 1%
Malathion 0.5%
Re-apply after 3 days
Shigella
Self limiting
Meningitis by Listeria
IV Amoxicillin + Gentamicin
Non-Gonoccocal Urethritis
Oral azithromycin or doxycycline
Mastitis during breast-feeding
Flucloxacillin
Mycobacterium Avium Intracellulare
Rifabutin, Ethambutol, Clarithromycin
Genital Warts
Topical Podophyllum or cryotherapy
Multiple non-keratinised warts –> topical agent
Single keratinised wart –> cryotherapy
Imiquimod –> topical cream –> second line
Most clear spontaneously in 1-2 years
PCP
Co-trimoxazole
Chlamydia
Doxycycline 7 day course OR Azithromycin (single dose - fist line)
CMV Retinitis
IV Ganciclovir
HSV1 and HSV2
Oral Aciclovir
Cellulitis
Flucloxacillin or Clarithromycin if allergic
Chikungunya
Sypmtomatic relief only
Japanese Encephalitis
Supportive
Hepatitis C Post Exposure Prohpylaxis
Monthly PCR
If seroconversion –> IFN +/- Ribavirin
Exacerbations of chronic bronchitis
Amoxicillin or tetracycline or clarithromycin
Throat infections
Phenoxymethylpenicillin(erythromycin alone if penicillin-allergic)
Clostridium difficile
First episode: metronidazole - Second or subsequent episode of infection: vancomycin
Syphillis
IM Benzathine Penicillin
OR Doxycycline
Lower urinary tract infection
Trimethoprim or nitrofurantoin. Alternative: amoxicillin or cephalosporin
Bacterial Vaginosis
Oral metronidazole 5-7 days
Listeria
Amoxicillin
Animal or human bite
Co-amoxiclav(doxycycline + metronidazole if penicillin-allergic)
Tularaemia
Doxycycline
Dengue
Symptomatic
Varicella Zoster Post Exposure Prohpylaxis if immunosuppressed or pregnant
VZV Immunolobulin for IgG negative women
Meningitis Empirical less than 3 months
GBS, E. Coli, Listeria
IV Cefotaxime + Amoxicillin
Invasive Aspergillosis
Voriconazole
Gingivitis: acute necrotising ulcerative
Metronidazole
Hepatitis B
Pegylated interferon-alpha
Acute prostatitis
Quinolone or trimethoprim
Acute pyelonephritis
Broad-spectrum cephalosporin or quinolone
Hepatitis C
Protease inhibitors +/- Ribavirin
i. e. Daclastasvir + Sofosbuvir
i. e. Sofosbuvir + Simeprevir
Shigellosis
Ciprofloxacin
Tetanus
Supportive
Periapical or periodontal abscess
Amoxicillin
Cysticercosis
Niclosamide
Erysipelas
Phenoxymethylpenicillin(erythromycin if penicillin-allergic)
Cutaneous Anthrax
Ciprofloxacin
Animal bites or Human bites
Co-Amoxiclav
IF allergy: Doxycycline + Metronidazole
Campylobacter enteritis
Clarithromycin
TB
R = Rifampicin I = Isoniazide P = Pyrazinamide E = Ethambutol
Active:
2 months RIPE followed by 4 months RI
Latent TB:
3 months of RI + Pyridoxine
or 6 months Isoniazid + Pyridoxine
Meningeal TB
Prolonged course + steroids
Otitis externa
Flucloxacillin(erythromycin if penicillin-allergic)
Malaria
Artemisinin-based combination therapy
Primaquine following acute therapy in Ovale and Virax to destroy liver hypnozoites
Typhus
Doxycycline
Otitis media
Amoxicillin(erythromycin if penicillin-allergic)
Trachomonas Vaginalis
Oral Metronidazole 5-7 days
Trypansomiasis American
Acute: Azole + Nitroderivative i.e. benznidazole or nifurtimox
Chronic: Treat complicaitons
Salmonella (non-typhoid)
Ciprofloxacin
H1N1 Influenza
Oseltamivir (neuraminidase inhibitor). Zanamivir (neuraminidase inhibitor)
MRSA
Mupirocin 2% for nose and Chlorhexidine soap
Vancomycin, Linezolid, Teicoplanin
Schistosomiasis
Praziquantel
Mycoplasma Pneumonia
Doxycycline or macrolide
Hepatitis B Post Exposure Prohpylaxis
HBsAg Positive Source:
- If known responder give booster
- If non-responder/not fully vaccinated give Hepatitis B Immune Globulin and Vaccine
Unknown Source:
- Consider booster dose HBV
- Non-responders: HBIG + Vaccine
- Being Vaccinated accelerate course of vaccine
Hydatid Disease
Albendazole
Sinusitis
Amoxicillin or doxycycline or erythromycin
Hospital-acquired pneumonia
Within 5 days of admission: co-amoxiclav or cefuroxime - More than 5 days after admission: piperacillin with tazobactam OR a broad-spectrum cephalosporin (e.g. ceftazidime) OR a quinolone (e.g. ciprofloxacin)
Cryptosporidoiosis
Support
Nitazoxanide if immunocompetent
Pneumonia possibly caused by atypical pathogens
Clarithromycin
HIV Post Exposure Prohpylaxis
Low Risk: No PEP
High Risk:
- Combination of oral antiretrovirals ASAP for 4 weeks (start 1-2 hours up to 72 hours)
- Serology testing at 12 weeks post completion
- Reduces risk of transmission by 80%
Giardiasis
Metronidazole
Meningitis Empirical 3 months to 50 years
IV Cefotaxime