Micro HSB- Midterm Flashcards

Myeloid Tissues

1
Q

What functions as storage for triglycerides, protects organs, and supports attachment and movement?

A

Bone

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2
Q

Formation of RBCs in bone marrow is called?

A

Hematopoiesis

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3
Q

What is a multipotential hematopoietic stem cell to common myeloid & lymphoid progenitors?

A

Hemocytoblast

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4
Q

Common features of Erythropoiesis are?

A
  1. No visible granules
  2. Round nucleus
  3. cells turn smaller per stage
  4. nucleus turn smaller per stage and extruded at last stage
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5
Q

Which is a mitotic cell with a nucleoli that makes RNA and has a basophilic cytoplasm?
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)

A

a. proerythroblast

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6
Q

Which has NO nucleoli that makes RNA and has an INTENSELY basophilic cytoplasm and is smaller than its previous form?
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)

A

b. basophilic erythroblast

intense basophilic cytoplasm is due to ribosomes (protein synthesis location)/ ribonucleic acid

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7
Q

Which is known for a checker board nucleus or light- dark pattern due to ribonucleic acid and an increase in hemoglobin?
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)

A

c. polychromatic erythroblast

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8
Q

Which is known as a “normoblast “ with a smaller pyknotic nucleus (extruded out), LAST STAGE with a nucleus, and pink cytoplasm due to hemoglobin accumulation?

a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)

A

d. orthochromatic erythroblast

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9
Q

Which has no nucleus, pink orange and blue in color, reticular networks found on cresyl blue (ribosomes)

a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)

A

e. polychromatic erythrocyte (reticulocyte)

high #: loss of mature RBC
low #: bone marrow malignancy, chemotherapy, aplastic/ pernicious anemia

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10
Q

what has adipose cells, not hematopoietic, found in long bones, singet rings for triglycerides?

a. red marrow
b. yellow marrow

A

b. yellow marrow

adipose cells increase as we age

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11
Q

what is an active hematopoietic stem cell that is highly vascular and large venous sinusoids found in epiphyses of long bones, flat, irregular, short bones?

a. red marrow
b. yellow marrow

A

a. red marrow

child: 100% red marrow
adult: 50% red marrow, 50% yellow marrow
elderly (70+): 30% red marrow

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12
Q

what disease has no adipocytes, and erythropoietic stem cell?

a. acute myelogenous leukemia
b. anemia
c. bleeding

A

a.acute myelogenous leukemia

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13
Q

low red blood cell count is called?

A

anemia

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14
Q

having no granulocytes exhibits what?

A

infections

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15
Q

having no platelet cells means?

A

bleeding

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15
Q

leukemic cell rapidly growing in a none expanding area of the bone causes what symptom in patients?

A

bone pain

16
Q

these are common features of ?
1. highly visible granules
2. nucleus shapes vary

A

granulopoiesis

17
Q

Large cell and nucleoli (more than one) , mitotically active, positive AZUROPHILIC non specific granules?

a. promyelocyte
b. metamyelocyte
c. band
d. neutrophil

A

a. promyelocyte

18
Q

what has + lilac stain, INDENTED ROUND NUCLEUS, mitotically active, purple stain azurophilic non specific granules?

a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil

A

b. myelocyte

19
Q

what has a smaller and FLAT nucleus, lilac stain specific granules positive?

a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil

A

c. metamyelocyte

20
Q

what has a horse shoe shape nucleus and lilac stain specific granules positive?

a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil

A

d. band

21
Q

what has a segmented lobe nucleus and lilac stain specific granules positive?

a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil

A

e. neutrophil

22
Q

what do you call platelet formation?

A

thrombopoiesis

23
Q

in platelet formation, which is a large cell with a SINGLE large nucleus, basophilic nongranular cytoplasm, divides mitotically but has no division?

a. megakaryoblast
b. megakaryocyte

A

a. megakaryoblast

24
Q

in platelet formation, which is an extremely large cell with a single large polyploid nucleus, precursor is promegakaryocyte that go thru to endomitosis, fragmenting to thrombocytes

a. megakaryoblast
b. megakaryocyte

A

b. megakaryocyte

25
Q
A