Micro HSB- Midterm Flashcards
Myeloid Tissues
What functions as storage for triglycerides, protects organs, and supports attachment and movement?
Bone
Formation of RBCs in bone marrow is called?
Hematopoiesis
What is a multipotential hematopoietic stem cell to common myeloid & lymphoid progenitors?
Hemocytoblast
Common features of Erythropoiesis are?
- No visible granules
- Round nucleus
- cells turn smaller per stage
- nucleus turn smaller per stage and extruded at last stage
Which is a mitotic cell with a nucleoli that makes RNA and has a basophilic cytoplasm?
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)
a. proerythroblast
Which has NO nucleoli that makes RNA and has an INTENSELY basophilic cytoplasm and is smaller than its previous form?
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)
b. basophilic erythroblast
intense basophilic cytoplasm is due to ribosomes (protein synthesis location)/ ribonucleic acid
Which is known for a checker board nucleus or light- dark pattern due to ribonucleic acid and an increase in hemoglobin?
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)
c. polychromatic erythroblast
Which is known as a “normoblast “ with a smaller pyknotic nucleus (extruded out), LAST STAGE with a nucleus, and pink cytoplasm due to hemoglobin accumulation?
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)
d. orthochromatic erythroblast
Which has no nucleus, pink orange and blue in color, reticular networks found on cresyl blue (ribosomes)
a. proerythroblast
b. basophilic erythroblast
c. polychromatic erythroblast
d. orthochromatic erythroblast
e. polychromatic erythrocyte (reticulocyte)
e. polychromatic erythrocyte (reticulocyte)
high #: loss of mature RBC
low #: bone marrow malignancy, chemotherapy, aplastic/ pernicious anemia
what has adipose cells, not hematopoietic, found in long bones, singet rings for triglycerides?
a. red marrow
b. yellow marrow
b. yellow marrow
adipose cells increase as we age
what is an active hematopoietic stem cell that is highly vascular and large venous sinusoids found in epiphyses of long bones, flat, irregular, short bones?
a. red marrow
b. yellow marrow
a. red marrow
child: 100% red marrow
adult: 50% red marrow, 50% yellow marrow
elderly (70+): 30% red marrow
what disease has no adipocytes, and erythropoietic stem cell?
a. acute myelogenous leukemia
b. anemia
c. bleeding
a.acute myelogenous leukemia
low red blood cell count is called?
anemia
having no granulocytes exhibits what?
infections
having no platelet cells means?
bleeding
leukemic cell rapidly growing in a none expanding area of the bone causes what symptom in patients?
bone pain
these are common features of ?
1. highly visible granules
2. nucleus shapes vary
granulopoiesis
Large cell and nucleoli (more than one) , mitotically active, positive AZUROPHILIC non specific granules?
a. promyelocyte
b. metamyelocyte
c. band
d. neutrophil
a. promyelocyte
what has + lilac stain, INDENTED ROUND NUCLEUS, mitotically active, purple stain azurophilic non specific granules?
a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil
b. myelocyte
what has a smaller and FLAT nucleus, lilac stain specific granules positive?
a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil
c. metamyelocyte
what has a horse shoe shape nucleus and lilac stain specific granules positive?
a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil
d. band
what has a segmented lobe nucleus and lilac stain specific granules positive?
a. promyelocyte
b. myelocyte
c. metamyelocyte
d. band
e. neutrophil
e. neutrophil
what do you call platelet formation?
thrombopoiesis
in platelet formation, which is a large cell with a SINGLE large nucleus, basophilic nongranular cytoplasm, divides mitotically but has no division?
a. megakaryoblast
b. megakaryocyte
a. megakaryoblast
