Micro - Hemorrhagic Fevers Flashcards
1
Q
List African hemorrhagic fevers
A
- Ebola
- Marburg
2
Q
List other hemorrhagic fevers
A
- Dengue fever
- Yellow fever
- Rift valley fever
3
Q
What happens to T-cells
A
- T-cell apoptosis leading to reduced immunity
4
Q
What happens to liver
A
Hepatic damage, resulting in reduced coagulation factors
5
Q
What happens to MQ’s
A
Increased pro inflammatory cytokines, leading to VD, vascular leaking, and endothelial damage.
6
Q
Reservoir hosts for Marburg and Ebola
A
Bats
7
Q
Diagnosis of Marburg and Ebola
A
- Direct ( Viral Ag via ELISA or nuclei acid via PCR )
- Indirect Igm or IgG via ELISA
8
Q
Prevention and treatment of Ebola and Marburg
A
- Supportive therapy like fluid and electrolytes, sometimes anticoagulants
- Vax for monkeys
9
Q
Yellow fever is a member of
A
Flavirdae
10
Q
Clinical picture of yellow fever
A
Mild : FAHM
Moderate : Jaundice & Renal problems
Sever : Hemorrhagic fever, Renal failure & black vomitous
11
Q
Prevention and treatment of yellow fever
A
- Supportive therapy
- Mosquito control
- 17D yellow fever live attenuated vaccine
12
Q
Dengue fever virus is a member of
A
Flavirdae
13
Q
Reservoir host of Dengue fever
A
Man
14
Q
About classic dengue fever
A
- FAHM
- Joint pain
- Myalgia
- Maculopapular rash
15
Q
Clinical picture of dengue fever
A
- Classic dengue fever
- Dengue hemorrhagic fever
- Dengue shock syndrome
