Micro Flashcards
Eukaryotes
True Nucleus
E.g. Human cells, protozoa
Prokaryotes
No True Nucleus, No Organelles
No mitochondria
E.g. Bacteria
IgA
Secretory antibody (mucosal antibody)
Mucous membrane (saliva, tears)
- buys time for body to ID invader
Found in Breast Milk
IgD
Helps IgG
IgE
Parasitic infections
Allergic reactions
Increased in Hodgkin’s Disease
IgG
First to increase (second exposure) Most numerous Crosses placenta Anamnestic response "without amnesia" - Body remembers disease and mounts same IgG response next time
IgM
Pentamer (10 binding sites) non - specific
largest and heaviest
First to increase (first exposure
Inclusion bodies: Aschoff
Rheumatic fever
Diptheria
Grey pseudomembrane in throat
Inclusion bodies: Downey cell
Mononucleosis
Atypical lymphocytes
Inclusion bodies: Gohn Comples
TB (inactive phase)
Calcium “jail” around mycobacterium
Inclusion bodies: Guarneri Bodies
Small pox (various)
Inclusion bodies: Gummas
Tertiary Syphilis
in brain
Inclusion bodies: Koplik spots
Measles - Rubeola/red measles
On Buccal mucosa white/bluish spots
Inclusion bodies: Lewy Bodies
Parkinson’s aka Paralysis Agitans
Shuffling/festinating gait
Inclusion bodies: Negri Bodies
Rabies (hydrophobia)
Inclusion bodies: Reed Sternberg
Hodgkin’s
Inclusion bodies: Russell Bodies
In plasma cells
consist of antibodies from chronic inflammation and malignant disorders
Multiple Myeloma
Active Immunity
Makes own antibodies
must actively make antibodies
natural Active Immunity
Exposed to disease
body reacts
triggers antibody production
Artificial Active Immunity
Injection of attenuated organism
inactivated portion that triggers immune system to make antibody
Passive Immunity
Receives antibodies outside
Given antibodies
Natural Passive Immunity
Given Ab in utero - IgG
breastfeeding - IgA
Artificial Passive Immunity
Injection of preformed antibodies
Pre-made antibody attacks circulating toxins not bound toxins
Hypersensitivity Reaction: Type I
Anaphylactic - Immediate
Rapid 12-30
Bronchial asthma (allergy), Bee sting, Hay fever
IgE, Mast cell, Basophils
Hypersensitivity Reaction: Type II
Cytotoxic Min - Hours Goodpasteur's (Lung & Kidney) Erythroblastosis fettles = coombs anemia Blood transfusions Myasthenia gravis Grave's disease - IgG involved, Targets cell for phagocytosis - 2 Things: Antigen & Antibody
Hypersensitivity Reaction: Type III
Immunecomplex mediated 3-10 hours Glomerulonephritis Lupus RA Arthus Rxn = local necrosis Serum sickness = systemic - IgG & Complement - 3 Things: Antigen & Antibody & Complememnt
Hypersensitivity Reaction Type IV
Delayed Hyper-sensitivity (aka cell-mediated aka cellular) 48 hours TB Contact dermatitis Transplat rejection - T-Cells - Lymphocytes
Autotroph
eats inorganic material
Heterotroph
eats organic material
Saprophyte
eats dead/decaying material
Parasite
eats off living organisms
Facultative
Presence OR absence of O2
Obligate
Only one environment, not the other (O2 only or no O2 only)
Microaerophilic
Reduced O2 envrionments
Symbiosis
2 populations living together one or both benefit
Mutualism
2 populations living together both benefit
Synergism
2 populations living together both benefit and both a accomplish what neither can do alone
Commensalism
2 populations living together one benefits and the other is unaffected
Zoonosis
transfer of disease from animal to human
Emerging
New disease or rapid increase of a disease in incidence or geographic range
Endemic
Small number of cases in specific location.
Present all the time
Epidemic
Rapidly affects many persons in a certain area within a few days or weeks
Etiology
Study of the cause of disease
Incidence
of NEW cases in a given time period
Pandemic
More than expected # of cases of a disease worldwide