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Meningoencephalitis, vesicular lesions
Herpes simplex virus-2
I ♥️ Rubi earrings
Rubella
Cataract
Deafness
Heart disease (PDA)
Blueberry muffin rash
CMV neonatal manifestations
Hearing loss Seizures Petechial rash Blueberry muffin rash PERIVENTRICULAR CALCIFICATIONS
Toxoplasma gondii
Triad
Chorioretinitis
Hydrocephalus
Intracranial calcifications
+/- blueberry muffin rash
Nitrite test
diagnostic ?
UTI caused by enterobacteriaceae
Reiter syndrome
Triad
Arthritis
Urethritis
Conjunctivitis
Reiter syndrome
Autoimmune reaction to a previous infection w/ one of th following org 👉shiguell, salmonella, yersinia, campylobacter, chlamydia
Chlamydia trachomatis
Unable to synthesize ?
ATP
Chlamydia
Elementary body ^ reticulate body functions ?
Elementary body 👉 enters cell
Reticulate body 👉 replicates in cell by fission
Owl’s eye inclusion
CMV
Basophilic intranuclear inclusion body
PYR + (2)
S pyogenes
Enterococci
C botulinum
4D’s
Diplopia
Dysarthria
Dysphagia
Dyspnea
Nocardia (5)
GRAM +
Aerobe Acid fast Soil Cause pulmonary inf, cutaneous inf TMP-SMX
Actinomyces (5)
GRAM +
Anaerobe Not acid fast Oral, reprod, GI flora Facial abscesses, sulfur granules Penicillin
TB
Inhibit phagolysosomal fusion ?
Sulfatides
Tuberculoid form
TH1
Treatment ? (2)
Dapsone
Rifampin
Lepromatous form
TH2
Treatment ? (3)
Dapsone
Rifampin
Clofazimine
EMB agar
Lactose fermenters grows as black/purple colonies
MacConkey agar
Pink colonies
Ferment lactose
Klebsiella
E coli
Enterobacter
Serratia
Bordetella pertussis
3 stages:
Catarrhal 🤒 coryza, fever
Paroxysmal 😥 whooping cough
Convalescent 😩
HUS
Causes ? (2)
Triad ?
EHEC O157:H7
Shiga- like toxin
Anemia, thrombocytopenia, ARF
H pylori treatment
Amoxi (metronidazole if penic allergy)
Clarithromycin
PPI
Leptospirosis
Symptoms ? (5)
Flu like Myalgias (calves) Jaundice Photophobia Conjunctival suffusion (erythema w/o exudate)
Lyme
DOC ?
Treatment in pregnant/ children ?
DOC: DOXYCYCLINE
pregnant: Amoxi, Cefuroxime
Ixodes deer tick
Transmission ? (3)
Borrelia burgdorferi
Anaplasma
Babesia microti
Secondary syphilis
Labs
VDRL/RPR (nonspecific)
FTA-ABS (specific)
Neurosifilis
Labs ?
VDRL
FTA-ABS
PCR
VDRL false ➕ ? (4)
Viral infection
Drugs
Rheumatic fever
Lupus and leprosy
Mulberry like inclusions
Monocytes = Ehrlichiosis
Morulae in cytoplasm
Granulocytes = anaplasmosis
Culture ➖ endocarditis
Coxiella burnetti
Transient arthralgia would be expected in an adult w/?
B19 virus
Rubella
Most important pathogenic attribute of pseudomonas aeruginosa in cystic fibrosis ?
Capsule: makes phagocytosis impossible
Generalized transduction
Error of lytic virus life cycle, any chromosomal DNA can be transferred
Specialized transduction
Error of temperate virus life cycle, genes near the virus insertion site may be transferred
Polyarticular arthritis in sexually active patients
Neisseria gonorrhoeae
N. Gonorrhoeae
🔹️Localized arthritis
🔹️Disseminated gonococcal dermatitis - arthritis sx triad ?
Dermatitis
Tenosynovitis
Polyarthritis
Nonimmunogenic capsules (2)
S pyogenes ➡️ hyaluronic acid
N meningitidis B ➡️ sialic acid
Ferment mannitol
Grows on mannitol salt agar
PYR ➖
S aureus
Boxcar shaped GRAM ➕ rod
Treatment ?
B anthracis
Cipro or doxycycline
Fever, chills, fatigue
Outdoor hiking trip
Small rings in RBC
Babesia microti
Dermacentor andersoni tick (3)
Colorado tick fever
RMSF
Francisella tularensis
Specialized transduction
Bacterial toxic factors acquired during lysogeny
COBEDS
Cholera toxin O ag of salmonella Botulinum exotoxin Erythrogenic exotoxins of S pyogenes Diphtheria toxin Shiga toxin
Mississippi-Ohio-Missouri river valleys w/ calcifying lung lesions ? (2)
Histoplasma
Blastomyces
HBV Window period serologic markers ? (2)
HBcAb
HBeAb
Postinfluenza bacterial pneumonia w/ cavitary lesions ^ salmon colored sputum
S aureus
Postinfluenza bacterial pneumonia w/ rusty sputum ?
S pneumoniae
RMSF pathogenesis ?
Intracellular infection of endothelial cells
Maternal CMV infection symptoms ?
Asymptomatic
Flulike symptoms
Maternal toxoplasma gondii infection
Symptoms?
Asymptomatic
Lymphadenopathy
Maternal rubella infection
Symptoms ?
Rash
Lymphadenopathy
Polyarthritis
Polyarthralgia
Property that provides TB with resistance to GRAM stain reagents ?
Mycolic acid
Members of the enterobacteriaceae
Nitrite- positive
E coli
K pneumoniae
Proteus mirabilis
Which virulence factor is responsible for the skin rash in scarlet fever ?
Pyrogenic exotoxin
Yersinia enterocolitica
Transmission ?
Pork
Milk
Which mechanism does S aureus use to protect itself from phagocytosis ?
Inhibition of opsonization
Parvovirus B19 receptor ?
P antigen on RBC
Genetic shift
Causes pandemics
Reassortment of viral genome segments
Superinfection
Worse prognosis
- HBV and then HDV
Lyme disease in a kid < 8 yrs
Treatment ?
AMOXICILLIN