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Product development > Micro > Flashcards

Micro Flashcards

1
Q

Candida albicans

Candida parapsilosis

A

Fungi

conjunctivitis

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2
Q

Klebsiella spp.

A

Gram (-) bacteria
conjunctivitis, infection
contaminant of artificial nails

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3
Q

Clostridium tetani

A

Gram (+) bacteria

tetanus

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4
Q

Clostridium perfringens

A

Gram (+) bacteria

gangrene

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5
Q

Pseudomonas aeruginosa

A

Gram (-) bacteria

conjunctivitis, infection

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6
Q

Malassezia furfur

A

Fungi

dermatomycosis

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7
Q

Enterobacteriaceae

A

Gram (-) bacteria

enteritis

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8
Q

Trichophyton spp.

A

Fungi

dermatomycosis

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9
Q

Aspergillus spp.

A

Fungi

allergic reaction

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10
Q

Gram positive bacteria

A

Staph/Strep
Enterococcus
Clostridiums

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11
Q

Gram negative bacteria

A

Pseudomonas
Klebsiella
Enterobacteriaceae

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12
Q

Fungi

A 
C. albicans/parapsilosis
Malassezia
Trichophyton
Trichoderma
Aspergillus
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13
Q

Blood agar is used to grow

A

pathogens

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14
Q

Sabouraud Dextrose broth is used to grow

A

mold

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15
Q

MacConkey Agar is used to grow

A

gram negative lactic fermenters

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16
Q

Mold or gram (+) bacteria likely is from

A

water or raw material source

17
Q

Most common source of contamination

A

water

18
Q

Typical water treatment steps could include

A
  • deionization
  • distillation
  • ultra-filtration
  • UV 220-290
  • reverse osmosis
  • heat 80-100 degrees centigrade
19
Q

Examples of cleansers

A
  • Strong mineral acids
  • Mild organic acids
  • Sufactants with solvents
  • Mild alkaline
  • Strong alkaline
20
Q

Strong mineral acid cleansers

A

Phosphoric

Sulfuric

21
Q

Mild organic acid cleansers

A

Glycolic

Citric

22
Q

Neutral cleansers

A

surfactants with solvents

alcohols/glycol ethers

23
Q

Mild alkaline cleansers

A

Phosphates
Carbonates
Borax

24
Q

Strong alkaline cleansers

A

Alkali hydroxides

25
Q

Sanitizer examples

A 
Formalin
Hypochlorites
Chloramines
Quats
Iodine
Alcohols
Hydrogen peroxide
26
Q

products with low micro risk

A

> 25% alcohol
antiperspirants
bath salts

27
Q

Nonsusceptable products

A

solvent based

anhydrous

28
Q

Microbial limit of baby products

A
29
Q

Microbial limit of eye products

A
30
Q

Microbial limit of other cosmetics

A
31
Q

Pathogens that must be absent

A

S. aureus
P. aeruginosa
E. coli

32
Q

Standard methods of preservative efficacy testing

A

CTFA M-3
USP
ASTM

33
Q

Challenge preservative to test efficacy with inoculums at

A

10^6

34
Q

Rechallenge/reinnoculation at

A

28 days

35
Q

criteria for preservative acceptance

A

Bacteria log 3 reduction (99.9% reduced Aerobic plate Count at 7-14 days)
Y/M 90% reduction

36
Q

Skin flora

A

Staphylococcus epidermidis
P. acnes
Corynebacterium xerosis

37
Q

What causes axillary odor

A

C. xerosis

Product development (7 decks)

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