Micro Flashcards
Genome + capsid
Nucleocapsid
Protein coat of viruses
Capsid
Individual subunits of capsids
Capsomeres
20 flat sided nucleocapsid
Icosahedral
Entirety of virus is called
Virion or viral particle
Steps in viral replication
Penetration Uncoating Macromolecular synth Assembly Release PUMAR
DNA containing viruses
HHAPPPy Hepadnaviridae Herpesviridae Adenoviridae Papovaviridae Poxviridae Parvoviridae
Causes RTI, keratoconjunctivitis, gastroentiritis
Childhood URTI
Adeno
Causes HBV or serum hepa
Dane’s particles
Blood, birth, boinking
Hepadna
Only DNA virus causing hepa
Hepa B
Indicative of active hepa dse
HBsAg
Anti HBsAg
Immune, cured, ni active dse
Tells how long the infxn has been going on
IgM and IgG anti HBcAG
Core antigen
Enveloped, indicates high infectivity and active dse
Enveloped dane particle
Causes herpes labialis, cold sore or fever blister, herpetic keratitis of cornea
HSV1
Causes herpes genitalis or venereal sore
HSV2
Causes varicella, HZ or shingles
VZV or HHv3
Causes Burkitt’s lymphoma (facial deformity), IM or kissing dse
Endemic in africa
HHV4 or EBV
Epstein barr virus
Causes congenital dse of newborn with owl eye looking inclusion bodies
HHV5 or CMV
Most common cause of Roseola infantum or Exanthem subitum
HHV6
Lesser common cause of RI and ES
HHV7
Causes Kaposi Sarcoma
HHV8 or KSHV
Causes common warts
HPV2,4
Plantar warts
HPV 1
Genital warts
HPV 6,11
Cervical warts and penile cancer
HPV16,18
Flat warts on face arms knees
3,10,28
2nd smallest dna virus
Papova
Vaccine for papova
Gardasil
Cevarex
Wart removal techniques
Cryofreezing liquid N
Laser
Surgery
Podophyllin resin
Polyoma virus that causes hemorrhagic cystitis
BK virus
Causes multifocal leukoencephalopathy
JC virus
Causes slapped cheek syndrome or erythema infectiosum or 5th dse
Transient aplastic anemia
Parvoviridae
Most complex nucleocapsid Variola or major smallpox Variola minor or alstrim Vaccinia or cowpox Molluscum contagiosum
Poxviridae
Doc for HSv2
Acyclovir
Doc for CMV
Gancyclovir
Causes lassa fever, H fever
Arenaviridae
Causes gastroenteritis, starlight
Astroviridae
Causes California encephalitis, sandfly fever, rift valley, fever thru sandfly
Bunyaviridae
Causes pneumonia, korean H fever, cerimean congo h fever, la Crosse encephalitis
Hantavirus under bunya
Norwalk virus causing gastroenteritis
Caliciviridae
Causes common colds in children, SARS, MERS-CoV
Coronavirus
Causes Hepa D in hepa B patients
Deltaviridae
Ebola virus and Marburg virus
Filoviridae