MHRA ADDITIONAL/MISCELLANEOUS Flashcards
1
Q
WHAT IS THE MEANING OF BLACK TRIANGLE SYMBOL?
A
NEWLY LICENSED MED, requires additional monitoring by the European Medicines Agency
About 5 years retained, longer if need be
ALL reactions? Report through Yellow Card Scheme for drugs w/ black triangle status.
2
Q
DOXYCYCLINE & CONTRACEPTIVES?
A
Non-enzyme inducing antibacterial so… no additional precautions are advised.
3
Q
875 cards
A
4
Q
DRUGS IN PREGNANCY CAUTIONED/AVOID? ESSENTIALLY HIGH-RISK DRUGS
A
ACEi/ARBs ANTIEPILEPTICS CYTOTOXICS LITHIUM ISOTRETINOIN (retinoids) WARFARIN
AMINOGLYCOSIDES ANTIDEPRESSANTS (1st- congenital heart defects 3rd- neonatal withdrawal symptoms, persistent pulmonary hypertension in newborn) BETA BLOCKERS BENZODIAZEPINES NSAIDS OPIOIDS PHENOTHIAZINES TETRACYCLINES
5
Q
IBUPROFEN IN PREGNANCY?
A
AVOID DURING THIRD TRIMESTER-> risk of closure of fetal ductus arteriosus in utero-> persistent pulmonary hypertension.
6
Q
Codeine during pregnancy?
A
DON’T USE DURING DELIVERY- RISK OF RESPIRATORY DEPRESSION/WITHDRAWAL SYMPTOMS
