Mg Flashcards
RDA and UL for men and women aged 19-30 and 31+
19-30 M: 400 mg/day
31+ M: 420 mg/day
19-30 W: 310 mg/day
31+ W: 320 mg/day
what enhances absorption of Mg
Vit D and Fructose
Facts about Mg
- ~50% absorbed from foods
- ~65% reabsorbed in kidneys
- Cofactor for over 300 metabolic reactions
- Over half of the U.S. does not get the recommended amounts
Is there a toxicity with Mg
There is when referring to supplementation. The UL is 350 but we cannot get a toxicity from food sources
What decreases absorption of Mg
- Fiber
- Phytates
- oxylates
- Increased alcohol
- phosphorus
- Some medications
- Calcium(over 2,000 mg/day)
- protein >94 g/day
Functions of Mg
- Makes up crystal lattice of bone
- Stored on top of bone for when deficiency occurs: also when we are low the kidneys absorb it a lot better.
- Cofactor for over 300 enzymes (protein,carb, fat metabolism)
- Activates ATP
- DNA and RNA transcription
- Relaxes: Skeletal muscles, smooth muscles in blood vessels and gi tract.
- Natural calcium blocker
Deficiencies…..(rare)
Most deficiencies are caused by other illnesses like: cvd, renal disease, diabetes. Increased urinary Mg excretion and inadequate absorption.
EARLY SIGNS:
-Loss of appetite, nausea, vomiting, fatigue, and weakness
LATER:
-numbness, tingling, muscle contractions, cramps, personality changes
What is a drug that depletes Mg and what is it used for?
Topamax: given to people with migraines. Very Harsh!!
What diseases does Mg help prevent?
- Blood pressure: Helps decrease hypertension
- Diabetes: *refer to paper
- CVD: increases blood pressure
- Osteoporosis: Mg very imp. to bones
- Kidney stones: Calcium based
- Migraines: 600 mg helped reduce headaches. if tied with MgOH then you only get so much in so you can take over the upper limit
- Constipation
Toxicities?
- If from food they usually do not occur unless someone has renal disease
- The UL is referring to supplementation
Unique symptoms of toxicity?
- Flushing, slurred speech, depression and paralysis
- There are many others but these are the abnormal ones
Good sources of Mg
Fish, Nuts, legumes, green leafy veggies, whole wheat products