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Drug Quiz 5 > METOPROLOL (Lopressor) > Flashcards

METOPROLOL (Lopressor) Flashcards

1
Q

Drug Classification

A

Beta blocker

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2
Q

Mechanism of Action

A

β1R – antagonist →inhibits extracellular calcium entry and calcium release from sarcoplasmic reticulum in cardiac cells → negative chronotropy, inotropy, dromotropy

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3
Q

Pharmacokinetics

A

Onset of Action = Immediate
Peak Effects = 20 minutes
Duration of Effect = 13-19 hours
Half-Life = 3-4 hours

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4
Q

Indications

A

Stable Narrow Complex Tachycardia (A-Fib, A-Flutter)

Stable SVT refractory to adenosine

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5
Q

Contraindications

A

Hypotension
Decompensated cardiogenic shock
Suspected cocaine ingestion

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6
Q

Side Effects

A

Bradycardia, hypotension, lethargy, dyspnea, wheezing, dizziness

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7
Q

Dose

A

(ADULT): 5mg slow IV, IO q 5min, max total dose 15mg

(PEDI): Not recommended

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8
Q

Precautions

A

May exacerbate asthma, COPD, bronchospasm, and CHF

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9
Q

Drug Interactions

A

Do not give to patient receiving IV Ca2+channel blockers, will increase risk of profound bradycardia
Additive effects with digoxin

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Drug Quiz 5 (4 decks)

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