Methylxanthines

Question 1

Theophylline brand name

Answer 1

Theocron

Question 2

Theophylline dosage forms

Answer 2

Er 21 hr tab
er 23 hr tab
er 24 hr cap
liquid

Question 3

Theophylline adult dosing

Answer 3

Acute exacerbation: loading dose, typically given IV as aminophylline, followed by maintenance IV infusion
Chronic management: smokers - 16mg/kg/day divided and non smokers - 13mg/kg/day divided
Doses based on serum concentrations target range 1-15 mcg/mland toxic is >20