methods Flashcards

1
Q

what are some objective methods of observing sleep?

A

actigraphy, brain imagery, depth electrodes, polysomnography

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2
Q

actigraphy

A

accelerometer - tells you how much you move (based on idea that if you’re not moving, you’re probably sleeping)

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3
Q

functional near infrared spectroscopy

A

similar to mri and eeg but less invasive - measures hemoglobin concentration and absorption of near infrared light

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4
Q

depth electrodes

A

yucky wires implanted into head for lots of days (not experimental! Meant for pre operative/diagnostic epilepsy non responsive to medication - basically only for treatment things - we just learn about sleep from these patients because the wires stay in their heads during both sleep and waking)

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5
Q

polysomnography

A

the gold standard in sleep research - eeg (brain), eog (eyes), emg(muscles), ekg (heartrate) - bunch of sensors on face

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6
Q

what does EEG measure?

A

sleep stages, sleep onset, anomalities

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7
Q

EOG

A

REM - eye movements: REM sleep and slow rolling eye movements in SWS

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8
Q

EMG

A

teeth grinding, restless leg, etc - muscle tonus - atonia characteristic of REM, body movement during sleep, and sleep disorders

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9
Q

EKG

A

heart conditions

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10
Q

what is the last part of the body to relax in sleep?

A

the face

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11
Q

what is bruxism?

A

teeth grinding

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12
Q

what are the sleep stages

A

nrem1, nrem 2, nrem3 (used to be stage 3 and 4), rem

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13
Q

nrem 1

A
  • Sleep onset
    • Hynogogic images
    • Rolling eyes
    • Diminished responsiveness
      Sleepiness felt before onset
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14
Q

nrem 2

A
  • Mixed freq, low ampp
    • K complex: bipolar wave (like slow wave 0-2 Hz, lasts .5 sec) that happens when the brain notices something in the outside world but decides to preserve sleep (thalamocortical gating) - also plays a role in memory consolidation
      Sleep spindle: associated with protective processes against neurodegeneration and with brain plasticity - studies try to stimulate sleep spindles in old people for their neuroprotective effects
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15
Q

nrem 3

A
  • Slow wave sleep/Delta 0-4hz
    • Characterized by a predominance of delta activity - slow and synchronized
    • Parasomnias, night terrors, sleep walking
    • Dont want to wake up from slow wave - will be groggy, cranky, headachey (i.e. only take a 20 minute nap or a 90 minute nap (then you cycle back))
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16
Q

REM

A
  • Rapid eye movements
    • Mixed frequencies
    • Atonia
    • Breathing and cardiac activity irregular
      Dreamings, nightmares, realistic and engaging mental activity
17
Q

k complexes

A

· Pattern with a sharp high amplitude spike, followed by a slower positive wave
· Present during stage 2 of NREM sleep
· Supposed to help the brain filter out irrelevant stimuli
· When the brain notices something disruptive, the brain responds with a K complex - maybe serving to inhibit further processing of the stimulus?
Brains mechanism for maintaining undisturbed sleep

18
Q

sleep spindles

A

· Bursts of rhythmic activity (freq range: 11-16Hz)
· Seen in central regions of the brain like the thalamas
· Role in information processing and memory consolidation during sleep
· Enhance memory and cognitive functions? Learning and problem solving?
Younger people have more sleep spindles