Metastatic Disease of Unknown Primary Flashcards
Which investigations should be performed in all patients with metastatic disease of unknown primary?
FBC, U+E, LFT, calcium, urinalysis, LDH
CXR
CT CAP
AFP + hCG
What investigation should be performed if lytic bone lesions are detected in metastatic disease of unknown primary?
Myeloma screen
What investigations should be performed directed towards symptoms in metastatic disease of unknown primary?
Endoscopy
What investigation should be performed in men with metastatic disease of unknown primary?
PSA
Testicular US (in men with germ cell tumours)
What investigation should be performed in women with metastatic disease of unknown primary?
CA 125 (if peritoneal malignancy or ascites)
Mammography (if clinical or pathological features compatible with breast cancer)