Metastatic disease Flashcards
Do metastatic tumours have cells similar to the primary tumour or the local cells that surround it?
Primary tumour
What name would be given to a tumour found in the lung identified to have come from a primary breast cancer?
metastatic breast cancer
What is the name given to metastatic tumours where the primary cancer is not clear?
cancer of unknown primary origin
What are the two most common routes of metastases?
1) lymphatic system
2) blood vessels
What are the 3 most common sites of metastases in bladder cancer?
- Bone
- Liver
- Lung
What are the 3 most common sites of metastases in breast cancer?
- Bone
- Lung
- Brain
What are the 3 most common sites of metastases in colon cancer?
1) liver
2) lung
3) peritoneum
What are the 5 most common sites of metastases in kidney cancer?
1) adrenal gland
2) bone
3) brain
4) liver
5) lung
What are the 5 most common sites of metastases in lung cancer?
1) bone
2) brain
3) liver
4) adrenal gland
5) other lung
What are the 4 most common sites of metastases in melanoma cancer?
1) bone
2) brain
3) liver
4) lung
What are the 3 most common sites of metastases in ovarian cancer?
- Liver
- Lung
- Peritoneum
What are the 3 most common sites of metastases in pancreatic cancer?
1) liver
2) lung
3) peritoneum
What are the 3 most common sites of metastases in prostate cancer?
1) adrenal gland
2) bone
3) liver
4) lung
What are the 3 most common sites of metastases in rectal cancer?
1) liver
2) lung
3) peritoneum
What are the 3 most common sites of metastases stomach cancer?
1) liver
2) lung
3) peritoneum
What are the 3 most common sites of metastases in thyroid cancer?
1) bone
2) liver
3) lung
What are the 5 most common sites of metastases in uterine cancer?
1) bone
2) liver
3) lung
4) peritoneum
5) vagina
What is the name given to multiple, round, well-defined lung secondaries?
Canon ball metastases
Give 3 cancer primaries associated with cannon ball metastases:
- Renal cell carcinomas
- Prostate cancer
- Choriocarcinoma
What blood test can be used to check for prostate cancer?
PSA
What blood test can be used to check for ovarian cancer?
Ca125
What three cancers are associated with raised alpha fetoprotein?
- Liver
- Ovarian
- Testicular
Name 9 blood tests used when investigating metastases of unknown origin:
1) FBC
2) U+Es
3) LFTs
4) calcium
5) LDH
6) PSA (men)
7) Ca125 (women)
8) hCG
9) alpha fetoprotein
Name 4 imaging techniques used to investigate metastases of unknown origin:
1) CT TAP
2) testicular ultrasound
3) mammogram
4) CXR
