Metastatic disease

Question 1

Do metastatic tumours have cells similar to the primary tumour or the local cells that surround it?

Answer 1

Primary tumour

Question 2

What name would be given to a tumour found in the lung identified to have come from a primary breast cancer?

Answer 2

metastatic breast cancer

Question 3

What is the name given to metastatic tumours where the primary cancer is not clear?

Answer 3

cancer of unknown primary origin

Question 4

What are the two most common routes of metastases?

Answer 4

1) lymphatic system
2) blood vessels

Question 5

What are the 3 most common sites of metastases in bladder cancer?

Answer 5

1. Bone
2. Liver
3. Lung

Question 6

What are the 3 most common sites of metastases in breast cancer?

Answer 6

1. Bone
2. Lung
3. Brain

Question 7

What are the 3 most common sites of metastases in colon cancer?

Answer 7

1) liver
2) lung
3) peritoneum

Question 8

What are the 5 most common sites of metastases in kidney cancer?

Answer 8

1) adrenal gland
2) bone
3) brain
4) liver
5) lung

Question 9

What are the 5 most common sites of metastases in lung cancer?

Answer 9

1) bone
2) brain
3) liver
4) adrenal gland
5) other lung

Question 10

What are the 4 most common sites of metastases in melanoma cancer?

Answer 10

1) bone
2) brain
3) liver
4) lung

Question 11

What are the 3 most common sites of metastases in ovarian cancer?

Answer 11

1. Liver
2. Lung
3. Peritoneum

Question 12

What are the 3 most common sites of metastases in pancreatic cancer?

Answer 12

1) liver
2) lung
3) peritoneum

Question 13

What are the 3 most common sites of metastases in prostate cancer?

Answer 13

1) adrenal gland
2) bone
3) liver
4) lung

Question 14

What are the 3 most common sites of metastases in rectal cancer?

Answer 14

1) liver
2) lung
3) peritoneum

Question 15

What are the 3 most common sites of metastases stomach cancer?

Answer 15

1) liver
2) lung
3) peritoneum

Question 16

What are the 3 most common sites of metastases in thyroid cancer?

Answer 16

1) bone
2) liver
3) lung

Question 17

What are the 5 most common sites of metastases in uterine cancer?

Answer 17

1) bone
2) liver
3) lung
4) peritoneum
5) vagina

Question 18

What is the name given to multiple, round, well-defined lung secondaries?

Answer 18

Canon ball metastases

Question 19

Give 3 cancer primaries associated with cannon ball metastases:

Answer 19

1. Renal cell carcinomas
2. Prostate cancer
3. Choriocarcinoma

Question 20

What blood test can be used to check for prostate cancer?

Answer 20

PSA

Question 21

What blood test can be used to check for ovarian cancer?

Answer 21

Ca125

Question 22

What three cancers are associated with raised alpha fetoprotein?

Answer 22

1. Liver
2. Ovarian
3. Testicular

Question 23

Name 9 blood tests used when investigating metastases of unknown origin:

Answer 23

1) FBC
2) U+Es
3) LFTs
4) calcium
5) LDH
6) PSA (men)
7) Ca125 (women)
8) hCG
9) alpha fetoprotein

Question 24

Name 4 imaging techniques used to investigate metastases of unknown origin:

Answer 24

1) CT TAP
2) testicular ultrasound
3) mammogram
4) CXR