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Gene Regulation and Expression > Metaphase to anaphase, spindle-assembly checkpoint > Flashcards

Metaphase to anaphase, spindle-assembly checkpoint Flashcards

- Chromosome alignment on metaphase plate (congression) - Dissolution of sister chromatid cohesion (anaphase onset) - Progression of anaphase (anaphase A and B) - Roles and mechanisms of spindle-assembly checkpoint

1
Q

How are chromosomes aligned on a metaphase plate

A
  • push and pull forces cooperate to align chromosomes
  • chromosome congression
  • interpolar/astral MT pushes towards the plus-end-directed kinesin-4,10 motor proteins
  • kinetochore-microtubule pulls chromosome
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2
Q

How do sister chromatids separate from each other upon the onset of anaphase

A
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Gene Regulation and Expression (10 decks)

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