Metaphase

Question 1

Describe the event

Answer 1

Max shortening and thickening of chromosomes;

Two Sister chromatids become clearly visible;

Spindle fibres attach to chromosomes at centromeres;

Line up at metaphase plate

Question 2

What happens at M check point?

Answer 2

Formation of spindle fibres apparatus;

Attachment of spindle fibres to kinetochores associated with centromere;

Activate regulatory protein;

Anaphase begin

Question 3

Fn of regulatory protein?

Answer 3

Complex activated enzyme separase;

Cleaves cohesins;

Sister chromatids separate

Question 4

Describe the roles of cohesin complexes

Answer 4

Mediate Sister chromatids adhesion at prophase of mitosis and meiosis(II);

Accurate separation and restoration of individual chromosomes