Metabolism Enzymes Flashcards

1
Q

Inducers

A

rifampcin, ethanol (why upramps acetominphen), tobacco smoke, St. John’s Wort, phenytoin, pherobarbital

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2
Q

Inhibitors

A

Grapefruit juice, ketocanazole, fluoxetine, HIV protease, erythromycin, azole fungals

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3
Q

Methanol poisoning

A

methanol hydrolyzed by alcohol dehydrogenase to FORMIC acid (metabolite), treat with ethanol (competitive inhibitor) for alcohol dehydrogenase

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4
Q

Ethylene glycol

A

ethylene glycol broken down by alcohol dehydrogenase to oxalic acid, treat with fomezipole (inhibiits alc dehydrogenase)

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