Metabolism

Question 1

what is a metabolome?

Answer 1

all the metabolites in a cell or system

Question 2

what are catabolic pathways?

Answer 2

Transform fuels into cell energy eg ATP, NADH, NADPH, FADH2

Question 3

what are anabolic pathways?

Answer 3

Require cell energy eg ATP ,NADH, NADPH, FADH2 to synthesize diverse macromolecules from small precursor molecules

Question 4

what are the diseases caused by metabolic deformities?

Answer 4

diabetes, cancer, neurodegeneration, heart disease, infection, inflammation and immunological dysfunction

Question 5

what is bioenergetics?

Answer 5

quantitative study of energy transductions in living cells/organisms/systems

Question 6

what is the thermodynamic equation for the change in free energy?

Answer 6

dG’0= -nFdE0

Question 7

what are the 4 ways electrons are transferred in metabolism?

Answer 7

1. directly
2. as hydride ions (H-)
3. as hydrogen ions (H+ and e-)
4. by direct combination or organic reductants with O2

Question 8

what is the terminal electron acceptor?

Answer 8

oxygen