Metabolism Flashcards

1
Q

Characteristics of the peptide bond

A

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2
Q

Covalent bonds

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3
Q

Hydrogen bonds

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4
Q

Ionic interactions

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5
Q

Van der Waals forces

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6
Q

Hydrophobic interactions

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7
Q

N linked glycosylation

A

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8
Q

Glutamine

A

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9
Q

Formation of of gamma-carboxyglutamate

A

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10
Q

6 reaction types defining metabolism

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11
Q

Glycolysis reaction 1

A

Enzyme: hexokinase
Reactant: glucose
Product: glucose-6-phosphate and a proton
Reaction:

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12
Q

Glycolysis reaction 2

A

Enzyme: phosphoglucose isomerase
Reactant: glucose-6-phosphate
Product: fructose-6-phosphate
Reaction:

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13
Q

Glycolysis reaction 3

A

Enzyme: phosphofructokinase
Reactant: fructose-6-phosphate
Product: fructose-1,6-biphosphate
Reaction:

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14
Q

Glycolysis reaction 4

A

Enzyme: aldolase
Reactant: fructose-1,6-biphosphate
Product: glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
Reaction:

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15
Q

Glycolysis reaction 5

A

Enzyme: triose phosphate isomerase (TPI)
Reactant: dihydroxyacetone phosphate
Product: glyceraldehyde-3-phosphate
Reaction:

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16
Q

Glycolysis reaction 6

A

Enzyme: glyceraldehyde 3-phosphate dehydrogenase
Reactant: 2 x glyceraldehyde-3-phosphate
Product: 2 x 1,3-biphosphoglycerate
Reaction:

17
Q

Glycolysis reaction 7

A

Enzyme: phosphoglycerate kinase
Reactant: 2 x 1,3-biphosphoglycerate
Product: 2 x 3-phosphoglycerate
Reaction:

18
Q

Glycolysis reaction 8

A

Enzyme: phosphoglycerate mutase
Reactant: 2 x 3-phosphoglycerate
Product: 2 x 2-phosphoglycerate
Reaction:

19
Q

Glycolysis reaction 9

A

Enzyme: enolase
Reactant: 2 x 2-phosphoglycerate
Product: 2 x phosphoenolpyruvate and 2 x water molecule
Reaction:

20
Q

Glycolysis reaction 10

A

Enzyme: pyruvate kinase
Reactant: 2 x phosphoenolpyruvate
Product: 2 x pyruvate
Reaction:

21
Q

3 possible pathways which the pyruvate molecules can take

A
  • alcoholic fermentation
  • generation of lactate
  • generation of acetyl CoA
22
Q

Alcoholic fermentation

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23
Q

Generation of lactate

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24
Q

Generation of acetyl CoA

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25
Q

Pyruvate dehydrogenase complex

A

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26
Q

Pyruvate decarboxylase

A

Function:

Prosthetic group:

27
Q

Lipoamide reductase-transacetylase

A

Function:

Prosthetic group:

28
Q

Dihydrolipoyl dehydrogenase

A

Function:

Prosthetic group:

29
Q

LDH

A

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30
Q

Creatine phosphate

A

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31
Q

Glycerol phosphate shuttle

A

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32
Q

Malate-aspartate shuttle

A

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33
Q

define coenzyme

A

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34
Q

Glucose metabolism in cancer

A

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