Metabolism Flashcards

1
Q

what are the three irreversible reactions of glycolysis

A

glucose+hexakinase—> glucose-6-phosphate
fructose-6-phosphate+ 6-phosphofructokinase –> fructose-1,6- bisphosphate
PEP+pyruvate kinase —> pyruvate

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2
Q

where does glycolysis occur?

A

mitochondrial membrane

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3
Q

where does the TCA cycle occur?

A

mitochondrial matrix

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4
Q

how many ATP are generated from one cycle of aerobic respiration

A

36

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5
Q

how many ATP are generated from one cycle of anaerobic respiration

A

2

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6
Q

What is the purpose of the TCA cycle?

A

to release NADH and FADH2 which can deliver their electrons into the ETC. Energy released from the electron transfer causes active transport of H+ ions across the
inner membrane, which drives the ATPase pump so ATP can be generated.

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7
Q

What is the final electron acceptor?

A

O2- forming water

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8
Q

How are fatty acids converted to pyruvate?

A

beta oxidation

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9
Q

What are the three rate determining enzymes of the TCA cycle?

A

pyruvate dehydrogenase
isocitrate dehydrogenase
alpha- ketaglutarate dehydrogenase

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