Metabolism Flashcards
what are the three irreversible reactions of glycolysis
glucose+hexakinase—> glucose-6-phosphate
fructose-6-phosphate+ 6-phosphofructokinase –> fructose-1,6- bisphosphate
PEP+pyruvate kinase —> pyruvate
where does glycolysis occur?
mitochondrial membrane
where does the TCA cycle occur?
mitochondrial matrix
how many ATP are generated from one cycle of aerobic respiration
36
how many ATP are generated from one cycle of anaerobic respiration
2
What is the purpose of the TCA cycle?
to release NADH and FADH2 which can deliver their electrons into the ETC. Energy released from the electron transfer causes active transport of H+ ions across the
inner membrane, which drives the ATPase pump so ATP can be generated.
What is the final electron acceptor?
O2- forming water
How are fatty acids converted to pyruvate?
beta oxidation
What are the three rate determining enzymes of the TCA cycle?
pyruvate dehydrogenase
isocitrate dehydrogenase
alpha- ketaglutarate dehydrogenase