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Biochem > Metabolism > Flashcards

Metabolism Flashcards

1
Q

recurrent precipitation of hexagonal cystine stone

A

Cysteinurea

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2
Q

What is the etiology of a disease that causes recurrent precipitation of hexagonal cystine stone:

A

Hereditary defect of renal PCT and intestinal amino acid transporter that prevents reabsorption of Cystine, Ornithine, Lysine, and Arginine (COLA).

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3
Q

How would you diagnose a dz that recurrent precipitation of hexagonal cystine stone

A

Urinary cyanide-nitroprusside test is diagnostic.

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4
Q

How would yuou diagnose a dz that results in recurrent precipitation of hexagonal cystine stone

A

Treatment: urinary alkalinization (eg, potassium citrate, acetazolamide) and chelating agents (eg, penicillamine)􏰀solubility of cystine stones; good hydration.

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5
Q

Lab findings for kidney stones composed of cystein

A

Faintly radi- opaque

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Biochem (6 decks)

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