Metabolism Flashcards
Define metabolism
Sum of all chemical processes necessary to make possible the characteristics of living cells
Photoautotrophs
- Light for energy
- Inorganic source C
- Inorganic source e-
Photoheterotrophs
- Light for energy
- Organic source C
- Organic source e-
Chemoautotrophs
- Inorganic source energy
- Inorganic source C
- Inorganic source e-
Chemoheterotrphs
- Organic compounds for energy
- Organic source C
- Organic source e-
Fuel Oxidation
Catabolism
Respiration
- Complex -> Simple
- Oxidative reactions
- electrons and protons removed + O added
- Occurs spontaneously - -dG
Biosynthesis
Anabolism
DNA synthesis
- Simple -> complex
- Reductive reactions + e-+H’s
- Reactions require energy
- Not spontaneous +dG
How do enzymes aid endothermic reactions?
They can pair exothermic + endothermic reactions together b./c endothermic reactions not spontaneous
What processes occur to convert metabolic fuels to organic compounds?
- Catabolism
- Small range of simple compounds
- Anabolism
3 main ways energy is released between catabolism and anabolism
- High energy bonds
- Reduced co-enzymes
- Conc. gradients
Breakdown of ATP
Catabolic
NAD(P)H
- Catabolic
- REDOX that accept hydride ions
- Solube co-enzyme
- Synthetic pathways
- Kept at high conc.
FADH2
- Catabolic
- Tightly held to enzymes
- REDOX not as high energy as NAD(P)H
How is metabolism regulated?
- Cells use fuel in correct form
- Set range so excess must be stored
- Waste products removed
Brain fuels
Glucose + Ketone bodies
Skeletal Muscle fuels
Stores glycogen when glucose plentiful
In fed state
- Liver -> Makes glycogen + fat when glucose plentiful
- Tissues take up excess glucose
- Adipose tissue -> stores fat
In fasting
- Liver release glucose + ketone bodies
- Adipose release fatty acids
- Tissues switch to fat use
Exercise
- Adipose release fatty acids
2. Liver release glucose