Metabolism Flashcards
1
Q
Good with other drugs
A
Pramipexole
2
Q
Use CYP 1A2/interact with fluvoxamine
A
ropinirole
rasagiline
ramelteon
tasimelteon
3
Q
Use P450
A
Selegiline
4
Q
Use 3A4
A
buspirone alprazolam suvorexant eszopiclone triazolam midazolam tasimelteon
5
Q
Use NADH
A
chloral hydrate
6
Q
Requires tests: liver monitoring
A
Tolcapone
7
Q
Uses 2C19
A
carisprodol to meprobate
ramelteon
8
Q
Which drugs interact with fluvoxamine?
A
Those that use 1A2 or 2C19
9
Q
Which use glucuronidation to inactivate?
A
oxazepam rotigotine midazolam alprazolam lorazepam oxazepam
10
Q
Which drugs don’t use metabolites?
A
oxazepam
lorazepam
11
Q
Which drug can you detect using hair follicles?
A
clonazepam
12
Q
Which drug interacts with cimetidine?
A
zaleplon
13
Q
Which drug uses ester hydrolysis to inactivate?
A
flumazenil
14
Q
Which drugs interact with AAAD?
A
L-dopa uses
carbidopa inhibits peripherally
15
Q
Which drugs inhibit COMT?
A
tolcapone
entacapone
