Metabolism

Question 1

What is GLUT 1 for?

Answer 1

Bumble Bee’s Best
1. Blood cell
2. Blood-brain barrier
3. Baby (fetus cells)

Question 2

What is GLUT 2 for?

Answer 2

Last Known Phrase Is
1. Liver
2. Kidney
3. Pancreas
4. Intestine

Question 3

What is GLUT 3 for?

Answer 3

No Problem
1. Neurons
2. Placenta

Question 4

What is GLUT 4 for?

Answer 4

My Friends
1. Muscle
2. Fat Cells (adipocytes)

Question 5

Classes of lipidss

Answer 5

• Bile salts
• Eicosanoids
• Steroid hormones
• Triacylglycerol
• Phospholipids/ Sphingolipids
• Vitamins (fat soluble)
• Cholesterol

Question 6

Bile salts

Answer 6

Help intestinal lipid digestions and uptake. In lumen.

Question 7

Eicosanoids

Answer 7

Many are derived from arachidonic acids. Four classes, prostaglandins, thromboxanes, leukotriens, and lipoxins.

Question 8

Steroid Hormones

Answer 8

Take part in regulation of a wide range of physiological functions

Question 9

Triacylglycerol

Answer 9

Stored in adipose tissue as energy storage., also serve as insulation and padding in organs

Question 10

Phospholipids/sphingolipids

Answer 10

Mainly play a wide range of structural roles

Question 11

Vitamins (fat soluble)

Answer 11

Four types of fat soluble vitamins: A, D, E, K, each promote different functions

Question 12

Cholesterol

Answer 12

Has essential structural functions, and it is a precursor for such as bile salts, steroid hormones and vitamin D

Question 13

Fatty Acid Structure

Answer 13

CH3(CH2)nCOO-
- CH3(CH2)n: hydrophobic hydrocarbon chain
- COO-: hydrophilic carboxyl group (ionized at pH7 from COOH) -> pKa of 4.8

• Free fatty acids insoluble, need to be transported through albumin lipid carrier

Question 14

Difference between saturated and unsaturated fatty acids?

Answer 14

• Unsaturated has both saturated single bonds and unsaturated double bonds (cis configuration)
• In humans, majority of fatty acids are saturated or mono-saturated