Metabolic Syndrome

Question 1

The hypothesis?

Answer 1

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Question 2

Discuss the epidemiology of MS

Answer 2

income inequality
activity levels
changes in food

Question 3

CVD - unestablished risk factors? (4)

Answer 3

left ventricular size
fibrinogen
lipids (other than cholesterol)
homocysteine

Question 4

CVD - established risk factors? (10)

Answer 4

age (2)
gender (2)
family history (1)
genes (1)
cholesterol (1)
alcohol (1)
hypertension (1)
smoking (3)
physical inactivity
stress

Question 5

Describe the structure of insulin

Answer 5

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Question 6

Describe the glucose uptake mechanism of insulin

Answer 6

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Question 7

Describe the mechanism of insulin release

Answer 7

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Question 8

Actions of insulin

Answer 8

Stimulates:
glucose uptake (GLUT4)
glycogenesis
glyolysis
production of TAGs

Inhibits:
gluconeogenesis
glucogenolysis
proteolysis

Question 9

Dicuss glucagon and its release mechanism

Answer 9

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Question 10

T1DM (4)

Answer 10

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Question 11

T2DM definition and phases

Answer 11

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Question 12

Lipotoxicity Model (7)

Answer 12

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Question 13

Insulin receptor

Answer 13

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Question 14

Lipoproteins & related Apos

Answer 14

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Question 15

Exogenous pathway

Answer 15

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Question 16

Endogenous pathway

Answer 16

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Question 17

Reverse cholesterol pathway

Answer 17

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Question 18

factors affecting blood cholesterol

Answer 18

diet
exercise
weight
smoking
genes
age
sex (before 55yrs, lower in women)

Question 19

factors affecting blood TAGs

Answer 19

insulin resistance
excess alcohol
hypothyroidism
medications
genes (rare)

Question 20

HDL catabolism

Answer 20

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Question 21

how does hypertension affect CV

Answer 21

turbulence and plaques

Question 22

atherosclerosis pathway

Answer 22

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Question 23

Population Health 5 Ways

give examples

Answer 23

Health promotion
Regulation of food for quality and safety
Tax to raise prices and modify behaviour
Regulation of advertising
Economic Policy

Question 24

Population Health - solution for Australia?

Answer 24

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Question 25

Describe the economic evaluation flow chart

Answer 25

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Question 26

Describe cost-effectiveness graph

Answer 26

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Question 27

Describe QALY graph

Answer 27

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Question 28

Applications of simulation models?

Answer 28

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Question 29

Adapting simulation models?

Answer 29

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Question 30

Surgical vs medical treatment of obesity?

Answer 30

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Question 31

Types of physical activity?

Answer 31

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Question 32

Genetics & obesity?

Answer 32

2 studies

Question 33

Epigenetics & obesity

Answer 33

poland wII | rat study

Question 34

Medical management of obesity?

Answer 34

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Question 35

Failure of diets

Answer 35

about ghrelin

Question 36

Obesity pharmacotherapy options?

Answer 36

3

Question 37

Phentermine and topiramate side effects

Answer 37

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Question 38

Types of bariatric surgery

Answer 38

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Question 39

Managing MS table

Answer 39

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