Metabolic pathways: lipid catabolism Flashcards

1
Q

Three reasons why fat is required

A
  1. As an energy source
  2. For essential fatty acids
  3. For fat-soluble vitamins
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2
Q

What does triglyceride consist of?

A

Glycerol and three fatty acids

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3
Q

What are the main products of fat digestion?

A
  1. Glycerol
  2. Fatty acids
  3. Mono glycerides
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4
Q

What enzyme attacks and cleaves chylomicrons at muscle and adipose tissue?

A

Lipoprotein lipase

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5
Q

What happens to free fatty acids in adipose tissue and muscle?

A

In adipose tissue: resynthesized into triacylglycerols, for storage
In muscle: oxidised to provide energy

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6
Q

What is Lipolysis?

A

Breakdown of lipids

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7
Q

What enzymes initially cleaves the stored fat in adipose tissue?

A

Hormone sensitive lipases (e.g. adrenaline sensitive)

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8
Q

What are the products of each Beta oxidation cycle?

A

1 acetyl-CoA
1 FADH2
1 NADH + H+
1 fatty acyl-CoA, shortened by 2 carbon atoms

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