Metabolic Pathways: Gluconeogenesis Flashcards
1
Q
When is gluconeogenesis the primary source of glucose?
A
overnight when hepatic glycogen is depleted
2
Q
What is gluconeogenesis?
A
synthesis of glucose within body from non-carbohydrate precursors
3
Q
What are the precursors of gluconeogenesis?
A
lactate, amino acids, glycerol
4
Q
What is gluconeogenesis essentially the reverse of?
A
glycolysis
5
Q
How many liver enzymes does it require?
A
4
6
Q
What is oxaloacetate?
A
the TCA cycle intermediate which accepts acetyl groups. It is synthesised during gluconeogenesis in the mitochondria
7
Q
Does gluconeogenesis consume energy?
A
yes
8
Q
What is the precursor in the Cori Cycle?
A
lactate
