Metabolic pathways Flashcards

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1
Q

Non-competitive inhibitors affect enzyme action by..

A

altering the shape of the active site of the enzyme

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2
Q

metabolic pathways can be controlled by feedback inhibitions where

A

an end product binds to an enzyme found at the start of the pathway

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3
Q

describe how a non-competitive inhibitor works

A

bind away from the active site, preventing the substrate from binding

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4
Q

suggest how the results would confirm that the inhibitor was non-competitive

A

increasing the initial alcohol concentration will have no effect on the results

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5
Q

describe how a substitution mutation would alter the gene coding for enzyme 1

A

one nucleotide is replaced with another

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6
Q

explain how a substitution mutation may cause the synthesis of a faulty enzyme

A

the sequence of amino acids is changed

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7
Q

why PKU results in a build-up of phenylalanine

A

phenylalanine cannot be broken down

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8
Q

why individuals with PKU can still produce melanin

A

they get tyrosine from their diet

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9
Q

state the term used to describe this type of diagnostic testing

A

post- natal screening

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10
Q

describe how brain damage can be prevented in babies diagnosed with PKU

A

low phenylalanine diet

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11
Q

digest why alkali was not added to each tube at the start of the investigation

A

to allow time for the reaction to take place

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12
Q

state the term which describes a metabolic pathway in which simple molecules are built up into complex molecules

A

anabolic

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