Metabolic Pathways

Question 1

Enzyme? Glucose –> G6P

Answer 1

Hexokinase; consumes an ATP

Question 2

Enzyme? G6P<—> Fructose 6 Phosphate

Answer 2

Isomerase

Question 3

Enzyme? Fructose-6-Phosphate –> Fructose ,6 Biphosphate

Answer 3

Phosphofructokinase-1, (PFK), consumes an ATP

Question 4

Fructose 1,6 Biphosphate <—> G3P, DHAP

Answer 4

Aldolase

Question 5

DHAP <—> G3P

Answer 5

Isomerase

Question 6

G3P <—> 1,3 Bisphosphoglycerate

Answer 6

Glyceraldehyde-3-P dehydrogenase; reduces NAD+ to NADH (for ETC)

Question 7

3-Phosphoglycerate <–> 2-Phosphoglycerate

Answer 7

Mutase

Question 8

1,3 Bisphosphoglycerate <—> 3-Phosphoglycerate

Answer 8

Phosphoglycerate kinase; creates ATP from ADP

Question 9

2-Phosphoglycerate <–> Phosphoenolpyruvate (PEP)

Answer 9

Enolase

Question 10

PEP —> Pyruvate

Answer 10

Pyruvate Kinase; creates ATP from ADP

Question 11

what is the gross and net yield of glycolysis of one glucose molecule?

Answer 11

Gross: 4 ATP, 2 NADH
Net: 2 ATP; 2 NADH (2 ATP used in steps 1 and 3 -“Investment”)

Question 12

Glucose –> ?

Answer 12

Glucose 6 Phosphate

Question 13

G6P <–> ?

Answer 13

Fructose 6 Phosphate

Question 14

Fructose 6-Phosphate —>

Answer 14

Fructose 1,6-bis Phosphate

Question 15

Fructose 1,6 Phosphate <–> ???

Answer 15

DHAP/G3P

Question 16

G3P <—>

Answer 16

1,3 Bisphosphoglycerate

Question 17

1,3 Bisphosphoglycerate <–>??

Answer 17

3Phosphoglycerate

Question 18

3PG <–>

Answer 18

2PG

Question 19

2PG <–> ??

Answer 19

Phosphoenolpyruvate (PEP)

Question 20

PEP –> ??

Answer 20

Pyruvate